Anthony R. Haight

Children's Cancer Therapy Development Institute — United States

Materials Science · Physical Sciences

18h-index1.2kcitations73works3.82yr avg
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Research Topics

Crystallization and Solubility Studies(20), X-ray Diffraction in Crystallography(18), Chemical Synthesis and Analysis(11), Asymmetric Synthesis and Catalysis(9), Catalytic C–H Functionalization Methods(8)

Publications73 total

Non-oncology orphan drug development: Productivity and probability of success
Drug Discovery Today·2025Open Access
Abstract CT116: A first-in-human phase 1 study on the safety, PK, receptor occupancy, and pharmacodynamic markers of SPX-303, a first-in-class LILRB2×PD-L1 bispecific antibody
Cancer Research·2025
BCL-X <sub>L</sub> –targeting antibody-drug conjugates are active in preclinical models and mitigate on-mechanism toxicity of small-molecule inhibitors
Science Advances·2024· 14 citedOpen Access
Abstract 2729: Discovery and characterization of LILRB2XPD-L1 bispecific antibody SPX-303
Cancer Research·2024· 1 cited
Preclinical Characterization of Catabolic Pathways and Metabolism of ABBV-011, a Novel Calicheamicin-Based SEZ6-Targeting Antibody-Drug Conjugate
Drug Metabolism and Disposition·2023· 5 cited
Selective Reduction of Cysteine Mutant Antibodies for Site-Specific Antibody–Drug Conjugates
Bioconjugate Chemistry·2023· 8 cited
Abstract 5663: Discovery and characterization of anti-LILRB2 antibody SPX-104
Cancer Research·2023
CCDC 1903328: Experimental Crystal Structure Determination
The Cambridge Structural Database·2020Open Access
CCDC 1903323: Experimental Crystal Structure Determination
The Cambridge Structural Database·2020Open Access
CCDC 1903324: Experimental Crystal Structure Determination
The Cambridge Structural Database·2020Open Access
CCDC 1903327: Experimental Crystal Structure Determination
The Cambridge Structural Database·2020Open Access
CCDC 1903298: Experimental Crystal Structure Determination
The Cambridge Structural Database·2020Open Access
CCDC 1903329: Experimental Crystal Structure Determination
The Cambridge Structural Database·2020Open Access
CCDC 1903307: Experimental Crystal Structure Determination
The Cambridge Structural Database·2020Open Access
CCDC 1903310: Experimental Crystal Structure Determination
The Cambridge Structural Database·2020Open Access
CCDC 1903304: Experimental Crystal Structure Determination
The Cambridge Structural Database·2020Open Access
CCDC 1903325: Experimental Crystal Structure Determination
The Cambridge Structural Database·2020Open Access
CCDC 1903305: Experimental Crystal Structure Determination
The Cambridge Structural Database·2020Open Access
CCDC 1903326: Experimental Crystal Structure Determination
The Cambridge Structural Database·2020Open Access
CCDC 1903297: Experimental Crystal Structure Determination
The Cambridge Structural Database·2020Open Access
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Frequent Co-authors

Brian Kotecki(17), Rodger F. Henry(14), David M. Barnes(14), Thaddeus S. Franczyk(12), Travis B. Dunn(12), Shashank Shekhar(12), Michael G. Fickes(11), Andrew R. Ickes(11), Jeremy Henle(11), José G. Napolitano(11), Summer D. Laffoon(10), V. S. Chan(10), Jerome A. Menzia(8), Shyamal I. Parekh(7), Timothy L. Stuk(6), Weijiang Zhang(6), David M. Barnes(5), Timothy A. Robbins(5), Margaret C. Hsu(5), Damian J. Krysan(5)