Nelson C. Di Paolo

Biochemistry, Genetics and Molecular Biology · Life Sciences

15h-index2.7kcitations30works1.02yr avg
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Research Topics

Virus-based gene therapy research(19), Viral Infectious Diseases and Gene Expression in Insects(10), Viral gastroenteritis research and epidemiology(8), Immune Response and Inflammation(5), RNA Interference and Gene Delivery(5)

Publications30 total

Targeted, safe, and efficient gene delivery to human hematopoietic stem and progenitor cells in vivo using the engineered AVID adenovirus vector platform
Molecular Therapy·2024Open Access
Targeted, safe, and efficient gene delivery to human hematopoietic stem and progenitor cells in vivo using the engineered AVID adenovirus vector platform
Molecular Therapy·2023· 17 citedOpen Access
Targeted, Safe, and Efficient Gene Delivery to Human Hematopoietic Stem and Progenitor Cells <i>In Vivo</i> Using Engineered Avid Adenovirus Vector Platform
Blood·2023
Modification of primary amines to higher order amines reduces in vivo hematological and immunotoxicity of cationic nanocarriers through TLR4 and complement pathways
Biomaterials·2019· 36 cited
Abstract 4781: Preclinical assessment of efficacy and safety of novel oncolytic adenovirus for therapy of disseminated lung cancer
Cancer Research·2019· 1 cited
Abstract 4781: Preclinical assessment of efficacy and safety of novel oncolytic adenovirus for therapy of disseminated lung cancer
Experimental and Molecular Therapeutics·2019
Modification of primary amines to higher order amines reduces in vivo hematological and immunotoxicity of cationic nanocarriers through TLR4 and complement pathways
2019· 1 citedOpen Access
Development of the triple-mutant oncolytic adenovirus for treatment of metastatic cancer by means of intravascular virus administration.
Journal of Clinical Oncology·2018
Interleukin 1α and the inflammatory process
Nature Immunology·2016· 542 citedOpen Access
13. Functional Role of Adenovirus Penton in Modulating In Vivo Properties of Liver-Targeted and Liver-Detargeted Adenovirus Variants
Molecular Therapy·2016Open Access
Interdependence between Interleukin-1 and Tumor Necrosis Factor Regulates TNF-Dependent Control of Mycobacterium tuberculosis Infection
Immunity·2016· 2 citedOpen Access
Interdependence between Interleukin-1 and Tumor Necrosis Factor Regulates TNF-Dependent Control of Mycobacterium tuberculosis Infection
Immunity·2015· 93 citedOpen Access
Recognition of Human Oncogenic Viruses by Host Pattern-Recognition Receptors
Frontiers in Immunology·2014· 11 citedOpen Access
IL-1α and Complement Cooperate in Triggering Local Neutrophilic Inflammation in Response to Adenovirus and Eliminating Virus-Containing Cells
PLoS Pathogens·2014· 49 citedOpen Access
The Analysis of Innate Immune Response to Adenovirus Using Antibody Arrays
Methods in molecular biology·2013· 6 cited
The Transcription Factor IRF3 Triggers “Defensive Suicide” Necrosis in Response to Viral and Bacterial Pathogens
Cell Reports·2013· 73 citedOpen Access
Interleukin-1 Receptor 2 Keeps the Lid on Interleukin-1α
Immunity·2013· 13 citedOpen Access
Nature 2007 Junt-2
2013
Coagulation Factor X Activates Innate Immunity to Human Species C Adenovirus
Science·2012· 163 citedOpen Access
Recombinant Adenoviruses for Vaccination
2012
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Frequent Co-authors

Dmitry M. Shayakhmetov(27), Phoebe L. Stewart(6), Svetlana Atasheva(6), Thalia Papayannopoulou(5), Jia Yao(4), Nico van Rooijen(3), Oleksandr Kalyuzhniy(3), Yoichiro Iwakura(3), Nicole Wagner(3), Henry Wyche(3), Tobias Junt(2), E. Ashley Moseman(2), Matteo Iannacone(2), Steffen Maßberg(2), Philipp A. Lang(2), Marianne Boes(2), Katja Fink(2), Sarah E. Henrickson(2), Thorsten R. Mempel(2), Sean P. J. Whelan(2)