Jun Ishihara

Nagasaki University — Japan

Chemistry · Physical Sciences

31h-index3.0kcitations270works8.22yr avg
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Research Topics

Synthetic Organic Chemistry Methods(74), Asymmetric Synthesis and Catalysis(55), Carbohydrate Chemistry and Synthesis(41), Microbial Natural Products and Biosynthesis(30), Chemical synthesis and alkaloids(28)

Publications270 total

Total Syntheses of (+)-Penicibilaenes A and B via Enantioselective Desymmetrization
Organic Letters·2026
An IL-12 renaissance: Engineering tumor-restricted IL-12 to improve solid tumor T cell therapies
Molecular Therapy·2025Open Access
Design and Synthesis of Cyclopropane Congeners of Resolvin E2 with Azidopropoxy Chain toward a Chemical Tool for Probing the Anti-inflammatory Activity
The Journal of Organic Chemistry·2025
DDEL-21. Tumor-collagen binding IL-12 Immunotherapy for recurrent Glioblastoma
Neuro-Oncology·2025Open Access
EXTH-61. Tumor-matrix binding anti-GITR antibody to overcome recurrent glioblastoma
Neuro-Oncology·2025Open Access
858 Tumour-localising IL-15 superagonist for intravenous delivery enhances survival and reduces toxicity in solid tumour models
Regular and Young Investigator Award Abstracts·2025Open Access
Abstract 6099: STEAP1 targeting CAR-T cells equipped with collagen-binding IL-12 for advanced prostate cancer
Cancer Research·2025
Abstract 3760: Local activation of immune cells and depletion of Tregs by tumor collagen-binding checkpoint immunotherapy
Cancer Research·2025
Abstract B010: Targeting Metastatic Prostate Cancer with STEAP1 CAR T Cells and Tumor-Localized Immunomodulation
Cancer Immunology Research·2025· 1 cited
Lamellarin D Acts as an Inhibitor of Type I Collagen Production
ChemMedChem·2025· 3 citedOpen Access
Harnessing the tumor microenvironment: targeted cancer therapies through modulation of epithelial-mesenchymal transition
Journal of Hematology & Oncology·2025· 93 citedOpen Access
Progress in Lewis-Acid-Templated Diels–Alder Reactions
Molecules·2024· 8 citedOpen Access
Progress in Lewis Acid Template-Mediated Diels-Alder Reaction
Preprints.org·2024· 1 citedOpen Access
Identification of Azalamellarin N as a Pyroptosis Inhibitor
Biological and Pharmaceutical Bulletin·2023· 1 citedOpen Access
Visible-Light-Induced Three-Component Radical Coupling of Selenocarbamates, Enones, and Allylstannanes with Diphenyl (2,4,6-trimethylbenzoyl)phosphine Oxide
Synlett·2023· 1 cited
Reaction Mechanism and Origin of Stereoselectivity in the Fluorination and Trifluoromethylthiolation of 2‐Bromoamides with AgF and AgSCF<sub>3</sub>
European Journal of Organic Chemistry·2023· 3 cited
1201 Collagen binding TNF reduces systemic toxicity and drives complete remission of established immunologically cold murine tumours
Regular and Young Investigator Award Abstracts·2023Open Access
1212 Bioengineered tumour-targeted interleukin-12 selectively cures murine triple-negative breast cancer (TNBC)
Regular and Young Investigator Award Abstracts·2023Open Access
Higher-order Bloch spheres: A generalized representation of electron spin states with azimuthal phase factor
arXiv (Cornell University)·2023Open Access
Concise Formal Synthesis on Solandelactone E Based on a Regioselective Cyclopropanation
Heterocycles·2023Open Access
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Frequent Co-authors

Susumi Hatakeyama(30), Keisuke Takahashi(18), Akio Murai(12), Naoki Kanoh(6), Keisuke Takahashi(4), Setsuya Shibahara(4), Keisuske Takahashi(3), Ayako Nakano(3), Kenji Morokuma(3), Fumiya Urabe(3), Yuuko Yamamoto(3), T Sugimoto(3), Michiko Midori(2), Yoshiharu Iwabuchi(2), Naoko Imai(2), Yoshikatsu Shimada(2), Hironori Fukumoto(2), Kohei Eto(2), Madoka Yoshino(2), Takehiro Fukuzaki(2)