William M. Shafer

Emory University — United States

Immunology and Microbiology · Life Sciences

59h-index12.0kcitations261works3.22yr avg
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Research Topics

Bacterial Infections and Vaccines(136), Reproductive tract infections research(118), Antibiotic Resistance in Bacteria(47), Antimicrobial Peptides and Activities(35), Syphilis Diagnosis and Treatment(32)

Publications259 total

The impact of dynamic mucosal baseline immune states on C. muridarum and N. gonorrhoeae infection outcomes in a murine menstruation model 3775
The Journal of Immunology·2025Open Access
Commensal Neisseria and Antimicrobial-Resistant Gonorrhea
Annual Review of Microbiology·2025· 1 citedOpen Access
Gentamicin induction of the gonococcal <i>hicAB</i> toxin-antitoxin-encoding system and impact on gene expression influencing biofilm formation and <i>in vivo</i> fitness in a strain-specific manner
mBio·2025Open Access
Gentamicin induction of the gonococcal <i>hicAB</i> toxin-antitoxin encoding system and impact on gene expression influencing biofilm formation and in vivo fitness in a strain-specific manner
2025Open Access
Murine modeling of menstruation identifies immune correlates of protection during Chlamydia muridarum challenge
PLoS Pathogens·2025Open Access
Experimental genital tract infection demonstrates Neisseria gonorrhoeae MtrCDE efflux pump is not required for in vivo human infection and identifies gonococcal colonization bottleneck.
UNC Libraries·2024Open Access
Experimental genital tract infection demonstrates Neisseria gonorrhoeae MtrCDE efflux pump is not required for in vivo human infection and identifies gonococcal colonization bottleneck
PLoS Pathogens·2024· 3 citedOpen Access
Structural and functional diversity of Resistance-Nodulation-Division (RND) efflux pump transporters with implications for antimicrobial resistance
Microbiology and Molecular Biology Reviews·2024· 23 citedOpen Access
Transcriptional responses of <i>Neisseria gonorrhoeae</i> to glucose and lactate: implications for resistance to oxidative damage and biofilm formation
mBio·2024· 7 citedOpen Access
Erratum for Balthazar et al., “A laboratory-based predictive pathway for the development of <i>Neisseria gonorrhoea</i> e high-level resistance to corallopyronin A, an inhibitor of bacterial RNA polymerase”
Microbiology Spectrum·2024Open Access
Murine modeling of menstruation identifies immune correlates of protection during <i>Chlamydia muridarum</i> challenge
2024Open Access
A laboratory-based predictive pathway for the development of <i>Neisseria gonorrhoeae</i> high-level resistance to corallopyronin A, an inhibitor of bacterial RNA polymerase
Microbiology Spectrum·2024· 1 citedOpen Access
Ensuring a sustained workforce to combat antibiotic resistance in the 21st century: the critical need for training the next-gen of scientists at the pre-doctoral level
Antimicrobial Agents and Chemotherapy·2024Open Access
Hormonal steroids induce multidrug resistance and stress response genes in Neisseria gonorrhoeae by binding to MtrR
Nature Communications·2024· 10 citedOpen Access
Transcriptional activation of <i>ompA</i> in <i>Neisseria gonorrhoeae</i> mediated by the XRE family member protein NceR
mBio·2023· 3 citedOpen Access
<i>Neisseria gonorrhoeae</i> MtrCDE Efflux Pump During <i>In Vivo</i> Experimental Genital Tract Infection in Men and Mice Reveals the Presence of Within-Host Colonization Bottleneck
2023Open Access
Hormonal steroids bind the <i>Neisseria gonorrhoeae</i> multidrug resistance regulator, MtrR, to induce a multidrug binding efflux pump and stress-response sigma factor
2023· 1 citedOpen Access
High-level <i>in vitro</i> resistance to gentamicin acquired in a stepwise manner in <i>Neisseria gonorrhoeae</i>
Journal of Antimicrobial Chemotherapy·2023· 9 citedOpen Access
Structural Basis of Peptide-Based Antimicrobial Inhibition of a Resistance-Nodulation-Cell Division Multidrug Efflux Pump
Microbiology Spectrum·2022· 24 citedOpen Access
Potent <i>In Vitro</i> and <i>Ex Vivo</i> Anti-Gonococcal Activity of the RpoB Inhibitor Corallopyronin A
mSphere·2022· 8 citedOpen Access
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Frequent Co-authors

Jacqueline T. Balthazar(11), Magnus Unemo(9), Ann E. Jerse(8), Corinne E. Rouquette-Loughlin(6), Kayla E. Hagman(5), Daniel Golparian(4), Jan Pohl(3), David S. Stephens(3), L E Martin(3), Feng Long(3), Edward Yu(3), X D Qu(2), Robert I. Lehrer(2), Ralph C. Judd(2), Susu M. Zughaier(2), Carlos del Rı́o(2), Lori A.S. Snyder(2), Douglas M. Warner(2), John K. Spitznagel(2), Peter A. Rice(2)