Carol MacKintosh

Biochemistry, Genetics and Molecular Biology · Life Sciences

50h-index11.0kcitations169works37.02yr avg
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Research Topics

14-3-3 protein interactions(46), Ubiquitin and proteasome pathways(31), Protein Kinase Regulation and GTPase Signaling(22), Metabolism, Diabetes, and Cancer(14), Photosynthetic Processes and Mechanisms(12)

Publications168 total

Opposing roles for AMPK in regulating distinct mitophagy pathways
Molecular Cell·2024· 37 citedOpen Access
Differential roles and regulation of the protein kinases PAK4, PAK5 and PAK6 in melanoma cells
Biochemical Journal·2022· 6 citedOpen Access
Faculty Opinions recommendation of PI3K drives the de novo synthesis of coenzyme A from vitamin B5.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2022
Faculty Opinions recommendation of Loss of ubiquitin-specific peptidase 18 destabilizes 14-3-3ζ protein and represses lung cancer metastasis.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2022
Publisher's Note: ZNRF2 is released from membranes by growth factors and, together with ZNRF1, regulates the Na+/K+ATPase
Journal of Cell Science·2022· 1 citedOpen Access
Faculty Opinions recommendation of Deeply conserved synteny resolves early events in vertebrate evolution.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2021
Glucocorticoid receptor Thr524 phosphorylation by MINK1 induces interactions with 14-3-3 protein regulators
Journal of Biological Chemistry·2021· 14 citedOpen Access
A PKB-SPEG signaling nexus links insulin resistance with diabetic cardiomyopathy by regulating calcium homeostasis
Nature Communications·2020· 49 citedOpen Access
Faculty Opinions recommendation of OHNOLOGS v2: a comprehensive resource for the genes retained from whole genome duplication in vertebrates.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2019
Faculty Opinions recommendation of Magic roundabout is an endothelial-specific ohnolog of ROBO1 which neo-functionalized to an essential new role in angiogenesis.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2019
Faculty Opinions recommendation of The Parkinson's disease-linked Leucine-rich repeat kinase 2 (LRRK2) is required for insulin-stimulated translocation of GLUT4.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2019
SPEG Controls Calcium Reuptake Into the Sarcoplasmic Reticulum Through Regulating SERCA2a by Its Second Kinase-Domain
Circulation Research·2018· 55 citedOpen Access
Faculty Opinions recommendation of A single phosphorylation site of SIK3 regulates daily sleep amounts and sleep need in mice.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2018
Faculty Opinions recommendation of Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2018
Recent advances in understanding the roles of whole genome duplications in evolution
F1000Research·2018· 27 citedOpen Access
Faculty Opinions recommendation of Skeletal muscle O-GlcNAc transferase is important for muscle energy homeostasis and whole-body insulin sensitivity.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2018
Faculty Opinions recommendation of A genomic lifespan program that reorganises the young adult brain is targeted in schizophrenia.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2017
Faculty Opinions recommendation of Inactivation of Capicua in adult mice causes T-cell lymphoblastic lymphoma.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2017Open Access
Modulators of 14-3-3 Protein–Protein Interactions
Journal of Medicinal Chemistry·2017· 278 citedOpen Access
Recent advances in understanding the roles of whole genome duplications in evolution
F1000Research·2017· 19 citedOpen Access
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Frequent Co-authors

Nick Morrice(10), Rachel Toth(9), Shuai Chen(8), David G. Campbell(6), Greg B. G. Moorhead(6), Pauline Douglas(6), Michele Tinti(5), Philip Cohen(4), Kathryn M. Geraghty(4), D. Grahame Hardie(4), Robert W. MacKintosh(4), J E Harthill(4), Sarah Meek(4), Barry Hon Cheung Wong(3), Catherine Johnson(3), Patricia T.W. Cohen(3), Philip Cohen(3), Kei Sakamoto(3), Hong Yu Wang(3), Chao Quan(3)