Juan J. Pérez‐Villar

Hospital Universitario de La Princesa — Spain

Immunology and Microbiology · Life Sciences

21h-index2.6kcitations27works0.02yr avg
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Research Topics

Immune Cell Function and Interaction(19), T-cell and B-cell Immunology(15), Cell Adhesion Molecules Research(5), Immunotherapy and Immune Responses(4), Monoclonal and Polyclonal Antibodies Research(4)

Publications27 total

Preclinical activity of anti-CCR7 immunotherapy in patients with high-risk chronic lymphocytic leukemia
Cancer Immunology Immunotherapy·2015· 18 citedOpen Access
Anti-CCR7 therapy exerts a potent anti-tumor activity in a xenograft model of human mantle cell lymphoma
Journal of Hematology & Oncology·2013· 39 citedOpen Access
Monoclonal Antibodies to Six-Transmembrane Epithelial Antigen of the Prostate-1 Inhibit Intercellular Communication <i>In vitro</i> and Growth of Human Tumor Xenografts <i>In vivo</i>
Cancer Research·2007· 99 citedOpen Access
Human monoclonal antibodies to a novel kidney cancer antigen inhibit target-induced angiogenesis and tumor cell growth and migration in vitro
Cancer Research·2007
Chemical genetics identifies Rab geranylgeranyl transferase as an apoptotic target of farnesyl transferase inhibitors
Cancer Cell·2005· 131 citedOpen Access
Selective Itk Inhibitors Block T-Cell Activation and Murine Lung Inflammation
Biochemistry·2004· 111 citedOpen Access
Phosphorylation of the Linker for Activation of T-Cells by Itk Promotes Recruitment of Vav
Biochemistry·2002· 47 cited
Nuclear localization of the tyrosine kinase Itk and interaction of its SH3 domain with karyopherin α (Rch1α)
International Immunology·2001· 33 cited
Engagement of the T lymphocyte antigen receptor regulates association of son-of-sevenless homologues with the SH3 domain of phospholipase Cγ1
European Journal of Immunology·2000· 8 citedOpen Access
Regulated association between the tyrosine kinase Emt/Itk/Tsk and phospholipase-C gamma 1 in human T lymphocytes.
PubMed·1999· 62 cited
Regulated Association Between the Tyrosine Kinase Emt/Itk/Tsk and Phospholipase-Cγ1 in Human T Lymphocytes
The Journal of Immunology·1999· 41 citedOpen Access
CD5 Negatively Regulates the T-Cell Antigen Receptor Signal Transduction Pathway: Involvement of SH2-Containing Phosphotyrosine Phosphatase SHP-1
Molecular and Cellular Biology·1999· 204 cited
Roles of Chemokines and Receptor Polarization in NK-Target Cell Interactions
The Journal of Immunology·1998· 97 cited
The CD94/NKG2 C-Type Lectin Receptor Complex
Current topics in microbiology and immunology·1998· 48 cited
The CD94/NKG2-A inhibitory receptor complex is involved in natural killer cell-mediated recognition of cells expressing HLA-G1
The Journal of Immunology·1997· 154 citedOpen Access
The CD94/NKG2 C-type lectin receptor complex
Immunologic Research·1997· 17 cited
The CD94/NKG2C-type lectin receptor complex in recognition of HLA class I molecules
Research in Immunology·1997· 5 cited
Structure and function of the CD94 C‐type lectin receptor complex involved in recognition of HLA class I molecules
Immunological Reviews·1997· 137 citedOpen Access
Implications for immunosurveillance of altered HLA class I phenotypes in human tumours
Immunology Today·1997· 761 cited
The CD94 and NKG2‐A C‐type lectins covalently assemble to form a natural killer cell inhibitory receptor for HLA class I molecules
European Journal of Immunology·1997· 275 cited
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Frequent Co-authors

Miguel López‐Botet(14), Marta Carretero(9), Steven B. Kanner(9), Ignacio Melero(7), Francisco Navarro(7), Teresa Bellón(6), Antonio Rodrı́guez(5), Kathleen O'Day(4), Gena S. Whitney(3), Manuel Llano(3), Cristina Bottino(2), Derek Hewgill(2), Manuel Llano(2), Marco Colonna(2), A Moretta(2), Tai-An Lin(2), Pia M. Challita-Eid(2), Kendall Morrison(2), Karen Morrison(2), Arthur Raitano(2)