Paul N. Devine

AstraZeneca (United Kingdom) — United Kingdom

Chemistry · Physical Sciences

29h-index5.5kcitations102works11.52yr avg
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Research Topics

Asymmetric Synthesis and Catalysis(27), Enzyme Catalysis and Immobilization(21), Chemical Synthesis and Analysis(18), Synthetic Organic Chemistry Methods(15), Carbohydrate Chemistry and Synthesis(13)

Publications102 total

Development of a Biocatalytic Aerobic Oxidation for the Manufacturing Route to Islatravir
Organic Process Research & Development·2024· 13 cited
RNA encoded peptide barcodes enable efficient <i>in vivo</i> screening of RNA delivery systems
Nucleic Acids Research·2024· 10 citedOpen Access
Engineered CHO cells as a novel AAV production platform for gene therapy delivery
Scientific Reports·2023· 13 citedOpen Access
Development of a Biocatalytic Aerobic Oxidation for the Manufacturing Route to Islatravir
2023· 4 citedOpen Access
A Peptide Barcode Based Approach for Efficient in vivo Screening of RNA Delivery Systems
2023· 1 citedOpen Access
A chemoenzymatic strategy for site-selective functionalization of native peptides and proteins
Science·2022· 53 cited
A kinase-cGAS cascade to synthesize a therapeutic STING activator
Nature·2022· 125 cited
Biocatalysis in drug discovery and development
Current Opinion in Chemical Biology·2020· 166 cited
Observations for the Present and Future – A Panel of Vendors’ Views on Technology
2020
Mass Activated Droplet Sorting (MADS) Enables High‐Throughput Screening of Enzymatic Reactions at Nanoliter Scale
Angewandte Chemie International Edition·2019· 158 citedOpen Access
Mass Activated Droplet Sorting (MADS) Enables High‐Throughput Screening of Enzymatic Reactions at Nanoliter Scale
Angewandte Chemie·2019· 19 citedOpen Access
Design of an in vitro biocatalytic cascade for the manufacture of islatravir
Science·2019· 603 cited
Trends in <i>Salmonella</i> serovars and antimicrobial resistance in pigs and poultry in Northern Ireland between 1997 and 2016
Veterinary Record·2019· 5 cited
Hemoprotein‐Catalyzed Cyclopropanation En Route to the Chiral Cyclopropanol Fragment of Grazoprevir
ChemBioChem·2019· 22 cited
A generic platform for the immobilisation of engineered biocatalysts
Tetrahedron·2018· 96 citedOpen Access
Extending the application of biocatalysis to meet the challenges of drug development
Nature Reviews Chemistry·2018· 415 cited
Synthesis of Grazoprevir, a Potent NS3/4a Protease Inhibitor for the Treatment of Hepatitis C Virus
Organic Letters·2018· 24 cited
The positive clinical impact of a BK virus screening programme
2018
Alkaline-encrusted pyelitis in a renal allograft: a case report
2018
Practical Synthesis of A Macrocyclic HCV Protease Inhibitor: A High-Yielding Macrolactam Formation
Organic Process Research & Development·2014· 17 cited
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Frequent Co-authors

Jeffrey C. Moore(8), Richard Desmond(8), Matthew D. Truppo(7), David M. Tschaen(7), R. P. Volante(7), David Pollard(6), Benjamin F. Mann(5), Robert A. Reamer(5), Donald R. Gauthier(5), A. I. MEYERS(5), Taeboem Oh(5), Fred J. Fleitz(4), Mark A. Huffman(4), Anna Fryszkowska(4), Oscar Alvizo(4), Da Duan(4), Iman Farasat(4), Zhiguo J. Song(4), Karl B. Hansen(4), Peter G. Dormer(4)