Jelske N. van der Veen

Medicine · Health Sciences

24h-index3.2kcitations37works0.02yr avg
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Research Topics

Liver Disease Diagnosis and Treatment(16), Cholesterol and Lipid Metabolism(12), Diet, Metabolism, and Disease(11), Drug Transport and Resistance Mechanisms(9), Peroxisome Proliferator-Activated Receptors(9)

Publications37 total

Hepatocyte-derived DPP4 regulates portal GLP-1 bioactivity, modulates glucose production, and when absent influences NAFLD progression
JCI Insight·2022· 12 citedOpen Access
Genetic screening reveals phospholipid metabolism as a key regulator of the biosynthesis of the redox-active lipid coenzyme Q
Redox Biology·2021· 15 citedOpen Access
Dietary phosphatidylcholine supplementation reduces atherosclerosis in Ldlr male mice2
The Journal of Nutritional Biochemistry·2021· 36 cited
Carboxylesterase 1d (Ces1d) does not contribute to cholesteryl ester hydrolysis in the liver
Journal of Lipid Research·2021· 12 citedOpen Access
Intestinal Phospholipid Disequilibrium Initiates an ER Stress Response That Drives Goblet Cell Necroptosis and Spontaneous Colitis in Mice
Cellular and Molecular Gastroenterology and Hepatology·2020· 38 citedOpen Access
Implication of phosphatidylethanolamine N-methyltransferase in adipocyte differentiation
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease·2020· 21 cited
Hepatic PEMT activity mediates liver health, weight gain, and insulin resistance
The FASEB Journal·2019· 60 cited
A role for phosphatidylcholine and phosphatidylethanolamine in hepatic insulin signaling
The FASEB Journal·2019· 64 citedOpen Access
Impaired Hepatic Phosphatidylcholine Synthesis Leads to Cholestasis in Mice Challenged With a High‐Fat Diet
Hepatology Communications·2019· 18 citedOpen Access
Vitamin E alleviates non-alcoholic fatty liver disease in phosphatidylethanolamine N-methyltransferase deficient mice
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease·2018· 63 cited
Intestinal de novo phosphatidylcholine synthesis is required for dietary lipid absorption and metabolic homeostasis
Journal of Lipid Research·2018· 44 citedOpen Access
Hepatic Expression of PEMT, but Not Dietary Choline Supplementation, Reverses the Protection against Atherosclerosis in Pemt/Ldlr Mice
Journal of Nutrition·2018· 10 citedOpen Access
A potential novel pathway to regulate cellular concentrations of the redox-active lipid coenzyme Q
Free Radical Biology and Medicine·2018
The critical role of phosphatidylcholine and phosphatidylethanolamine metabolism in health and disease
Biochimica et Biophysica Acta (BBA) - Biomembranes·2017· 1.4k cited
Fenofibrate, but not ezetimibe, prevents fatty liver disease in mice lacking phosphatidylethanolamine N-methyltransferase
Journal of Lipid Research·2017· 24 citedOpen Access
Pioglitazone attenuates hepatic inflammation and fibrosis in phosphatidylethanolamine<i>N</i>-methyltransferase-deficient mice
American Journal of Physiology-Gastrointestinal and Liver Physiology·2016· 43 cited
Lack of phosphatidylethanolamine N -methyltransferase in mice does not promote fatty acid oxidation in skeletal muscle
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids·2015· 6 cited
Lack of phosphatidylethanolamine N-methyltransferase alters hepatic phospholipid composition and induces endoplasmic reticulum stress
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease·2015· 49 cited
Insufficient glucose supply is linked to hypothermia upon cold exposure in high-fat diet-fed mice lacking PEMT
Journal of Lipid Research·2015· 14 citedOpen Access
Vagus nerve contributes to the development of steatohepatitis and obesity in phosphatidylethanolamine N-methyltransferase deficient mice
Journal of Hepatology·2014· 23 cited
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Frequent Co-authors

René L. Jacobs(21), Dennis E. Vance(20), Folkert Kuipers(11), Susanne Lingrell(8), Rick Havinga(7), Randal C. Nelson(5), Jean E. Vance(4), Albert K. Groen(4), Antonio Gómez‐Muñoz(4), John P. Kennelly(3), Sereana Wan(3), Uwe J.F. Tietge(3), Vincent W. Bloks(3), Jonathan M. Curtis(3), Zamaneh Kassiri(3), Xia Gao(3), Aducio Thiesen(3), Kelly‐Ann Leonard(3), Marijke Schreurs(3), Niels Nijstad(3)