Sara af Bjerkén

Umeå University — Sweden

Medicine · Health Sciences

11h-index511citations24works4.52yr avg
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Research Topics

Parkinson's Disease Mechanisms and Treatments(12), Nerve injury and regeneration(9), Neuroscience and Neuropharmacology Research(7), Neurogenesis and neuroplasticity mechanisms(6), Neurotransmitter Receptor Influence on Behavior(5)

Publications24 total

Synergetic effect of a DSP4-induced locus coeruleus lesion and systemic LPS exacerbates substantia nigra dopaminergic neuron loss
Scientific Reports·2025Open Access
<i>N</i> -acetylcysteine increases dopamine release and prevents the deleterious effects of 6-OHDA on the expression of VMAT2, α-synuclein, and tyrosine hydroxylase
Neurological Research·2024· 9 citedOpen Access
Amphetamine-induced dopamine release in rat: Whole-brain spatiotemporal analysis with [<sup>11</sup>C]raclopride and positron emission tomography
Journal of Cerebral Blood Flow & Metabolism·2023· 2 citedOpen Access
Reliability and validity of visual analysis of [18F]FE-PE2I PET/CT in early Parkinsonian disease
Nuclear Medicine Communications·2023· 3 cited
N-acetylcysteine decreases dopamine transporter availability in the non-lesioned striatum of the 6-OHDA hemiparkinsonian rat
Neuroscience Letters·2021· 6 cited
VNTR polymorphism in the SLC6A3 gene does not influence dopamine transporter availability measured by [18F]FE-PE2I PET or [123I]FP-Cit SPECT
Nuclear Medicine Communications·2021
Noradrenaline is crucial for the substantia nigra dopaminergic cell maintenance
Neurochemistry International·2019· 19 cited
1H NMR profiling of the 6-OHDA parkinsonian rat brain reveals metabolic alterations and signs of recovery after N-acetylcysteine treatment
Molecular and Cellular Neuroscience·2019· 30 cited
Dopamine transporter imaging with [18F]FE-PE2I PET and [123I]FP-CIT SPECT—a clinical comparison
EJNMMI Research·2018· 78 citedOpen Access
An altered blood–brain barrier contributes to brain iron accumulation and neuroinflammation in the 6-OHDA rat model of Parkinson’s disease
Neuroscience·2017· 68 cited
Dampened Amphetamine-Stimulated Behavior and Altered Dopamine Transporter Function in the Absence of Brain GDNF
Journal of Neuroscience·2017· 41 citedOpen Access
Embryonic and mature astrocytes exert different effects on neuronal growth in rat ventral mesencephalic slice cultures
SpringerPlus·2015· 3 citedOpen Access
Degradation of proteoglycans affects astrocytes and neurite formation in organotypic tissue cultures
Brain Research·2014· 8 cited
The age of the astrocytes affects neuronal growth
2014
Serotonergic nerve fibers in l-DOPA-derived dopamine release and dyskinesia
Neuroscience·2013· 22 cited
Dopamine release from serotonergic nerve fibers is reduced in<scp>L</scp>‐DOPA‐induced dyskinesia
Journal of Neurochemistry·2011· 46 citedOpen Access
Histological studies of the effects of chronic implantation of ceramic-based microelectrode arrays and microdialysis probes in rat prefrontal cortex
Brain Research·2009· 100 citedOpen Access
Chronic intermittent<scp>L</scp>‐DOPA treatment induces changes in dopamine release
Journal of Neurochemistry·2008· 33 cited
Inhibition of astrocytes promotes long‐distance growing nerve fibers in ventral mesencephalic cultures
International Journal of Developmental Neuroscience·2008· 9 cited
On dopamine neurons : nerve fiber outgrowth and L-DOPA effects
2008
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Frequent Co-authors

Ingrid Strömberg(13), Greg A. Gerhardt(7), Ana Virel(7), Jan Axelsson(5), François Pomerleau(4), Susanna Jakobson Mo(4), Martin Lundblad(4), Anne Larsson(3), David Bäckström(3), Nina Nevalainen(3), Sanaz Hashemian(3), Lars Jonasson(2), Mattias Ögren(2), Andrea Varrone(2), Linda Eriksson(2), Katrine Riklund(2), Greger Orädd(2), M. Angela Cenci(2), Rutger Laterveer(2), Nina Karalija(2)