Edward D. Crandall

Hastings Center — United States

Medicine · Health Sciences

54h-index9.6kcitations227works0.12yr avg
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Research Topics

Neonatal Respiratory Health Research(64), Ion Transport and Channel Regulation(51), Inhalation and Respiratory Drug Delivery(44), Ion channel regulation and function(31), Hemoglobin structure and function(16)

Publications226 total

Claudin 4 Deletion Improves Gut Permeability and Survival in a Murine Model of Abdominal Sepsis
Shock·2026
Cross-talk Between ATF6 and Mammalian Target of Rapamycin Signaling Impairs Alveolar Epithelial Type 2 Cell Function and Differentiation During Lung Fibrosis
American Journal of Respiratory and Critical Care Medicine·2025
Bioelectric Changes in Primary Rat Alveolar Epithelial Cell Monolayers Exposed to Various Nanoplastics
Physiology·2025
Increased AEC Susceptibility to Injury Due to Autophagic Overload After Exposure to Nanoparticles
American Journal of Respiratory and Critical Care Medicine·2025
In-house Fabrication of Nanoplastics of Tunable Composition and Application: Assessment of Bioelectric Changes in Primary Rat Lung Alveolar Epithelial Cell Monolayers Exposed to Nanoplastics
BIO-PROTOCOL·2025· 1 citedOpen Access
Effects of nanoparticles on sensitivity to injury and role of autophagy in alveolar epithelial cells
Physiology·2024
Real-Time Autophagic Flux Measurements in Live Cells Using a Novel Fluorescent Marker DAPRed
BIO-PROTOCOL·2024Open Access
Kinetics of macroautophagy in lung adenocarcinoma (A549) cells exposed to nanoparticles
Physiology·2023
Kinetics of autophagic activity in nanoparticle-exposed lung adenocarcinoma (A549) cells
Autophagy Reports·2023· 3 citedOpen Access
Autophagic activity in response to nanoparticle exposure of A549 cells
The FASEB Journal·2022
Biokinetic Modeling of Nanoparticle Interactions with Lung Alveolar Epithelial Cells
The FASEB Journal·2021
Characteristics of Passive Solute Transport across Primary Rat Alveolar Epithelial Cell Monolayers
Membranes·2021· 5 citedOpen Access
Biokinetic modeling of nanoparticle interactions with lung alveolar epithelial cells: uptake, intracellular processing, and egress
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology·2020· 7 citedOpen Access
Epithelial Vegfa Specifies a Distinct Endothelial Population in the Mouse Lung
Developmental Cell·2020· 236 citedOpen Access
Nanoparticle Fate in Alveolar Epithelial Cells: Uptake, Distribution and Exocytosis
SHILAP Revista de lepidopterología·2020Open Access
Epithelial Vegfa specifies a distinct endothelial population in the mouse lung
2019· 16 citedOpen Access
Evidence for Nanoparticle-Induced Lysosomal Dysfunction in Lung Adenocarcinoma (A549) Cells
International Journal of Molecular Sciences·2019· 29 citedOpen Access
Transcriptional control of lung alveolar type 1 cell development and maintenance by NK homeobox 2-1
Proceedings of the National Academy of Sciences·2019· 111 citedOpen Access
Evidence for Nanoparticle-Induced Lysosomal Dysfunction in Alveolar Epithelial Cells
2019
Single-Cell RNA Sequencing of Aquaporin 5 (Aqp5)-Positive Epithelial Cells in Adult Mouse Lung Reveals Heterogeneity of Type I Cells and Facilitates Identification of Gprc5a as a Potential Novel Type I Cell Marker
2019
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Frequent Co-authors

Zea Borok(29), Kwang‐Jin Kim(13), Per Flodby(10), Beiyun Zhou(8), Lucas DeMaio(7), Spencer I. Danto(7), Janice M. Liebler(6), Parviz Minoo(6), Stephanie M. Zabski(6), David K. Ann(5), Nazanin R. Yacobi(5), Barbara E. Goodman(5), Farnoosh Fazlollahi(4), Richard L. Lubman(4), Sarah F. Hamm‐Alvarez(4), Robert Förster(4), Brigham C. Willis(3), Crystal N. Marconett(3), Yong Ho Kim(3), Danping Gao(3)