Ada Serroni

Thomas Jefferson University — United States

Pharmacology, Toxicology and Pharmaceutics · Life Sciences

16h-index1.8kcitations23works0.02yr avg
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Research Topics

Drug-Induced Hepatotoxicity and Protection(12), Liver Disease Diagnosis and Treatment(4), Liver physiology and pathology(4), Metabolism and Genetic Disorders(4), Mitochondrial Function and Pathology(3)

Publications23 total

Re‐evaluation of the distinction between type I and type II cells: The necessary role of the mitochondria in both the extrinsic and intrinsic signaling pathways upon fas receptor activation
Journal of Cellular Physiology·2006· 16 cited
Induction of the mitochondrial permeability transition mediates the killing of HeLa cells by staurosporine.
PubMed·2001· 110 cited
Independent antioxidant action of vitamins E and C in cultured rat hepatocytes intoxicated with allyl alcohol
Biochemical Pharmacology·1996· 21 cited
The Absence of Extracellular Calcium Potentiates the Killing of Cultured Hepatocytes by Aluminum Maltolate
Archives of Biochemistry and Biophysics·1995· 10 cited
Cyclosporin and carnitine prevent the anoxic death of cultured hepatocytes by inhibiting the mitochondrial permeability transition
Journal of Biological Chemistry·1993· 294 citedOpen Access
Cellular pool of transient ferric iron, chelatable by deferoxamine and distinct from ferritin, that is involved in oxidative cell injury.
Molecular Pharmacology·1992· 136 cited
The killing of cultured hepatocytes by N-acetyl-p-benzoquinone imine (NAPQI) as a model of the cytotoxicity of acetaminophen
Biochemical Pharmacology·1991· 38 cited
Metabolism of acetaminophen by cultured rat hepatocytes
Biochemical Pharmacology·1990· 34 cited
Evidence for the participation of activated oxygen species and the resulting peroxidation of lipids in the killing of cultured hepatocytes by aryl halides
Toxicology and Applied Pharmacology·1990· 8 cited
Protein thiol depletion and the killing of cultured hepatocytes by hydrogen peroxide
Biochemical Pharmacology·1989· 53 cited
Effects of ouabain on potassium transport and cell volume regulation in rat and rabbit liver.
The Journal of Physiology·1989· 6 citedOpen Access
Mitochondrial damage as a mechanism of cell injury in the killing of cultured hepatocytes by tert-butyl hydroperoxide
Archives of Biochemistry and Biophysics·1989· 126 cited
The inhibition of lipid peroxidation by disulfiram prevents the killing of cultured hepatocytes by allyl alcohol, tert-butyl hydroperoxide, hydrogen peroxide and diethyl maleate
Chemico-Biological Interactions·1989· 15 cited
Peroxidation-dependent and peroxidation-independent mechanisms by which acetaminophen kills cultured rat hepatocytes
Archives of Biochemistry and Biophysics·1988· 37 cited
1,3-(2-Chloroethyl)-1-nitrosourea potentiates the toxicity of acetaminophen both in the phenobarbital-induced rat and in hepatocytes cultured from such animals.
Molecular Pharmacology·1988· 19 cited
Killing of cultured hepatocytes by the mixed-function oxidation of ethoxycoumarin
Biochemical Pharmacology·1986· 9 cited
Oxygen-mediated cell injury in the killing of cultured hepatocytes by acetaminophen
Biochemical and Biophysical Research Communications·1985· 93 cited
Mechanisms of cell injury in the killing of cultured hepatocytes by bromobenzene.
Journal of Biological Chemistry·1982· 136 citedOpen Access
Accelerated phospholipid degradation and associated membrane dysfunction in irreversible, ischemic liver cell injury
Journal of Biological Chemistry·1978· 406 citedOpen Access
Intracellular calcium homeostasis in galactosamine-intoxicated rat liver cells
Archives of Biochemistry and Biophysics·1977· 32 cited
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Frequent Co-authors

John L. Farber(14), J L Farber(8), Marlene E. Kyle(7), Donna Gilfor(3), Dai Nakae(3), Jack W. Snyder(2), Marco Tafani(2), Ronald J. Gerson(2), Alessandro Casini(2), Isao Sakaida(2), Kenneth R. Chien(1), Jacki Abrams(1), José Martin(1), John G. Pastorino(1), Jan B. Hoek(1), Sherif El-Mofty(1), M.C. Scrutton(1), Claudio Nicolini(1), Ronald J. Rothman(1), A Casini(1)