Marie‐Lise Maddelein

Centre National de la Recherche Scientifique — France

Biochemistry, Genetics and Molecular Biology · Life Sciences

26h-index3.0kcitations47works0.02yr avg
OpenAlex↗ORCID↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Prion Diseases and Protein Misfolding(24), Trace Elements in Health(14), Neurological diseases and metabolism(14), Alzheimer's disease research and treatments(7), Sphingolipid Metabolism and Signaling(5)

Publications47 total

N-Heterocyclic Carbene-Iridium Complexes as Photosensitizers for In Vitro Photodynamic Therapy to Trigger Non-Apoptotic Cell Death in Cancer Cells
Molecules·2023· 8 citedOpen Access
Sphingosine Kinase-1 Is Overexpressed and Correlates with Hypoxia in Osteosarcoma: Relationship with Clinicopathological Parameters
Cancers·2022· 2 citedOpen Access
Sphingosine kinase-1 is overexpressed and correlates with hypoxia in osteosarcoma: relationship with clinicopathological parameters
HAL (Le Centre pour la Communication Scientifique Directe)·2021Open Access
An Artemisinin‐Derivative–(NHC)Gold(I) Hybrid with Enhanced Cytotoxicity through Inhibition of NRF2 Transcriptional Activity
Angewandte Chemie International Edition·2020· 42 citedOpen Access
An Artemisinin‐Derivative–(NHC)Gold(I) Hybrid with Enhanced Cytotoxicity through Inhibition of NRF2 Transcriptional Activity
Angewandte Chemie·2020· 9 cited
Artemisinin-Derivative-NHC-gold(I)-Hybrid with Enhanced Cytotoxic Activity Through Inhibiting NRF2 Transcriptional Activity
2020Open Access
Artemisinin-Derivative-NHC-gold(I)-Hybrid with Enhanced Cytotoxic Activity Through Inhibiting NRF2 Transcriptional Activity
2020· 1 citedOpen Access
Sphingosine kinase‑1 predicts overall survival outcomes in non‑small cell lung cancer patients treated with carboplatin and navelbine
Oncology Letters·2019· 26 citedOpen Access
Pharmacomodulation on Gold-NHC complexes for anticancer applications – is lipophilicity the key point?
European Journal of Medicinal Chemistry·2018· 53 cited
Neuronal sphingosine kinase 2 subcellular localization is altered in Alzheimer’s disease brain
Acta Neuropathologica Communications·2018· 45 citedOpen Access
Discovery of Novel Inhibitors of Amyloid β-Peptide 1–42 Aggregation
Journal of Medicinal Chemistry·2012· 39 citedOpen Access
P2‐244: Heat shock proteins alter <i>in vivo</i> abeta amyloid peptide aggregation
Alzheimer s & Dementia·2011
The Mechanism of Prion Inhibition by HET-S
Molecular Cell·2010· 95 citedOpen Access
Copper Transfer from Cu–Aβ to Human Serum Albumin Inhibits Aggregation, Radical Production and Reduces Aβ Toxicity
ChemBioChem·2009· 88 cited
P2‐173: Internalization of Abeta amyloid peptides in neuronal cells depending of their sequence and their structural assembly
Alzheimer s & Dementia·2009
A Non-Q/N-Rich Prion Domain of a Foreign Prion, [Het-s], Can Propagate as a Prion in Yeast
Molecular Cell·2007· 90 citedOpen Access
Prion and Non-prion Amyloids of the HET-s Prion forming Domain
Journal of Molecular Biology·2007· 69 cited
Critical Role for Sphingosine Kinase-1 in Regulating Survival of Neuroblastoma Cells Exposed to Amyloid-β Peptide
Molecular Pharmacology·2007· 56 cited
Prion and non-prion amyloids of the HET-s prion forming domain.
HAL (Le Centre pour la Communication Scientifique Directe)·2007
Infectious Fold and Amyloid Propagation in<i>Podospora anserina</i>
Prion·2007· 6 citedOpen Access
page 1 of 3Next →

Frequent Co-authors

Reed B. Wickner(12), Olivier Cuvillier(11), Sven J. Saupe(10), Herman K. Edskes(9), André Decq(7), Brigitte Delrue(7), Steven Ball(6), Kimberly L. Taylor(6), Heinz Gornitzka(6), Catherine Hemmert(6), Pierre‐Yves Fortin(6), Nathalie Libessart(5), Hiromitsu Moriyama(5), Christian Bijani(5), Grégory Mouille(4), N. Van den Koornhuyse(4), Daniel C. Masison(4), Christophe d’Hulst(4), Brian Roberts(4), Chen Zhang(4)