Alise Žagare

University of Luxembourg — LU

Medicine · Health Sciences

10h-index2.1kcitations31works2.62yr avg
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Research Topics

Parkinson's Disease Mechanisms and Treatments(15), Single-cell and spatial transcriptomics(6), Nuclear Receptors and Signaling(5), Microbial Metabolic Engineering and Bioproduction(4), Pluripotent Stem Cells Research(3)

Publications31 total

Parkinson's Disease Patient‐Specific Striatum Organoids Show Hallmarks of Increased Inflammation
Movement Disorders·2026Open Access
The Parkinson’s disease-associated LRRK2-G2019S variant restricts serine metabolism, leading to microglial inflammation and dopaminergic neuron degeneration
Journal of Neuroinflammation·2025· 2 citedOpen Access
Reproducibility of PD patient-specific midbrain organoid data for in vitro disease modeling
iScience·2025Open Access
Autophagy Dysfunction in iPSCs-Derived Neurons and Midbrain Organoids Carrying a <i>SNCA</i> Triplication
2025Open Access
Vascularized midbrain assembloids show neuroinflammation and dopaminergic neuron vulnerability in Parkinson’s Disease
2025Open Access
Parkinson’s disease microglia induce endogenous α-synuclein pathology in patient-specific midbrain organoids
2025Open Access
Reproducibility of PD patient-specific midbrain organoid data for in vitro disease modelling
2025Open Access
MIRO1 mutation leads to metabolic maladaptation resulting in Parkinson’s disease-associated dopaminergic neuron loss
npj Systems Biology and Applications·2025· 1 citedOpen Access
α‐Synuclein Pathology Spreads in a Midbrain–Hindbrain Assembloid Model
Advanced Science·2025· 6 citedOpen Access
Deciphering shared molecular dysregulation across Parkinson’s disease variants using a multi-modal network-based data integration and analysis
npj Parkinson s Disease·2025· 6 citedOpen Access
Parkinson’s disease mutant Miro1 causes mitochondrial dysfunction and dopaminergic neuron loss
Brain·2025· 9 citedOpen Access
Cystatin C Secretion in Blood Derivatives and Cellular Models of Idiopathic Parkinson’s Disease
Parkinson s Disease·2025Open Access
Insulin resistance compromises midbrain organoid neuronal activity and metabolic efficiency predisposing to Parkinson’s disease pathology
Journal of Tissue Engineering·2025· 8 citedOpen Access
Insulin Resistance Is a Modifying Factor for Parkinson's Disease
Movement Disorders·2024· 10 citedOpen Access
Deciphering shared molecular dysregulation across Parkinson’s Disease variants using a multi-modal network-based data integration and analysis
2024Open Access
Insulin resistance compromises midbrain organoid neural activity and metabolic efficiency predisposing to Parkinson’s disease pathology
2024· 3 citedOpen Access
Parkinson’s disease patient specific striatum organoids show hallmarks of increased inflammation
University of Luxembourg·2024Open Access
Parkinson’s disease-related Miro1 mutation induces mitochondrial dysfunction and loss of dopaminergic neurons <i>in vitro</i> and <i>in vivo</i>
2023· 2 citedOpen Access
Impaired neuron differentiation in GBA-associated Parkinson’s disease is linked to cell cycle defects in organoids
npj Parkinson s Disease·2023· 27 citedOpen Access
Omics data integration suggests a potential idiopathic Parkinson’s disease signature
Communications Biology·2023· 21 citedOpen Access
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Frequent Co-authors

Jens C. Schwamborn(23), Paul Antony(9), Sarah Nickels(9), Cláudia Saraiva(9), Anna S. Monzel(7), Kyriaki Barmpa(7), Gemma Gomez‐Giro(7), Elisa Zuccoli(7), Isabel Rosety(6), Rejko Krueger(6), Enrico Glaab(6), Ronan M. T. Fleming(5), Catarina Serra-Almeida(5), Daniela Frangenberg(5), Laurent Heirendt(4), Almut Heinken(4), Hulda S. Haraldsdóttir(4), Stefanía Magnúsdóttir(4), German Preciat(4), Jennifer Modamio(4)