Sreeja Karathedath

Christian Medical College & Hospital — India

Medicine · Health Sciences

7h-index226citations18works0.02yr avg
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Research Topics

Acute Myeloid Leukemia Research(11), Drug Transport and Resistance Mechanisms(6), Chronic Myeloid Leukemia Treatments(6), Retinoids in leukemia and cellular processes(3), Histone Deacetylase Inhibitors Research(3)

Publications18 total

Modulating retinoid-X-receptor alpha (RXRA) expression sensitizes chronic myeloid leukemia cells to imatinib in vitro and reduces disease burden in vivo
Frontiers in Pharmacology·2023· 5 citedOpen Access
Genetic Ablation of Nuclear Receptor Interacting Protein 1 (NRIP1) Sensitizes Acute Myeloid Leukemia Cells to Retinoic Acids
Blood·2021· 3 cited
Plasma imatinib levels and ABCB1 polymorphism influences early molecular response and failure-free survival in newly diagnosed chronic phase CML patients
Scientific Reports·2020· 11 citedOpen Access
Global Gene Expression Analysis Reveals Genotoxic Effect of Nrf2 Pharmacological Inhibitor Brusatol in Myeloid Leukemia Cells- a Promising Novel Anticancer Agent
Blood·2018· 1 cited
Abstract 3739: Nuclear hormone receptors modulate imatinib resistance in chronic myeloid leukemia (CML)
Cancer Research·2018
Role of NF-E2 related factor 2 (Nrf2) on chemotherapy resistance in acute myeloid leukemia (AML) and the effect of pharmacological inhibition of Nrf2
PLoS ONE·2017· 83 citedOpen Access
Atp-Binding Casette Transporter Expression in Acute Myeloid Leukemia: Association with <i>in Vitro</i> Cytotoxicity and Prognostic Markers
Pharmacogenomics·2017· 28 cited
Population pharmacokinetics of Daunorubicin in adult patients with acute myeloid leukemia
Cancer Chemotherapy and Pharmacology·2016· 21 citedOpen Access
Role of NF-E2 Related Factor 2 (NRF2) on Chemotherapy Resistance in Acute Myeloid Leukemia (AML) and the Effect of Pharmacological Inhibition of NRF2
Blood·2015· 8 cited
RNA Expression of Genes Involved in Cytarabine Metabolism and Transport Predicts Cytarabine Response in Acute Myeloid Leukemia
Pharmacogenomics·2015· 44 citedOpen Access
Population Pharmacokinetics of Daunorubicin in AML: Influence on Clinical Outcome
Blood·2014
Effect of cytosine arabinoside metabolizing enzyme expression on drug toxicity in acute myeloid leukemia
Annals of Hematology·2014· 10 cited
Expression Profiling Of Nuclear Hormone Receptors In Myeloid Leukemia Reveals Potential Novel Drug Targets For Combination Therapy
Blood·2013· 1 cited
Harnessing Gene Expression Profiling In Search Of New Candidate Genes For Ara-C Resistance In Acute Myeloid Leukemia
Blood·2013· 2 cited
NPM1 Mutated AML Is Associated With Lower Expression Of Poor Prognostic Markers BAALC, ERG and MN1 In Adult Patients With Acute Myeloid Leukaemia
Blood·2013· 1 cited
Novel<i>NPM1</i>mutation in the 3’-untranslated region identified in two patients with acute myeloid leukemia
Leukemia & lymphoma/Leukemia and lymphoma·2013· 1 cited
ABCB6 RNA expression in leukemias—expression is low in acute promyelocytic leukemia and FLT3-ITD-positive acute myeloid leukemia
Annals of Hematology·2013· 7 cited
ABC Transporter Expression in Acute Myeloid Leukemia: Association with in Vitro Cytotoxicity and Prognostic Markers
Blood·2012

Frequent Co-authors

Poonkuzhali Balasubramanian(18), Vikram Mathews(17), Ajay Abraham(13), Savitha Varatharajan(13), Alok Srivastava(11), Shaji R Velayudhan(9), Bharathi M. Rajamani(8), Biju George(8), Aby Abraham(7), Vivi M. Srivastava(6), Kavitha M. Lakshmi(5), Ashok Kumar Jayavelu(4), Raveen Stephen Stallon Illangeswaran(4), Ezhilpavai Mohanan(3), Auro Viswabandya(3), Sukanya Ganesan(3), Esther Sathya Bama Benjamin(3), Chepsy C Philip(2), Nancy Beryl Janet(2), Wei Zhang(2)