V. Politi

Nerviano Medical Sciences — Italy

Biochemistry, Genetics and Molecular Biology · Life Sciences

15h-index755citations35works0.02yr avg
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Research Topics

Protease and Inhibitor Mechanisms(9), Venomous Animal Envenomation and Studies(9), Tryptophan and brain disorders(5), Neuroscience and Neuropharmacology Research(4), Stress Responses and Cortisol(4)

Publications35 total

Non-drug Therapy Through Multisensory Stimulation for Patients with Severe Dementia: Multisensory Stimulation Lab (MS-Lab) Project
Lecture notes in bioengineering·2024
Gene Expression Profiling Reveals Cross-talk between Melanoma and Fibroblasts: Implications for Host-Tumor Interactions in Metastasis
Cancer Research·2005· 102 cited
Synthesis and evaluation of new tripeptide phosphonate inhibitors of MMP-8 and MMP-2
European Journal of Medicinal Chemistry·2005· 23 cited
Molecular dynamics simulation of Matrix Metalloproteinase 2: fluctuations and time evolution of recognition pockets
Journal of Computer-Aided Molecular Design·2003· 13 cited
The Enol Tautomer of Indole-3-Pyruvic Acid as A Biological Switch in Stress Responses
Advances in experimental medicine and biology·2003· 20 cited
Modulation of the Catalytic Activity of Neutrophil Collagenase MMP-8 on Bovine Collagen I
Journal of Biological Chemistry·2002· 44 citedOpen Access
Inhibition of contact hypersensitivity reaction to picryl chloride: effect of small molecular weight peptidomimetic compounds possessing inhibitory activity against metalloproteinases
International Immunopharmacology·2002· 10 citedOpen Access
pH- and Temperature-Dependence of Functional Modulation in Metalloproteinases. A Comparison between Neutrophil Collagenase and Gelatinases A and B
Biophysical Journal·2000· 71 citedOpen Access
Cleavage of Bovine Collagen I by Neutrophil Collagenase MMP-8
Journal of Biological Chemistry·2000· 26 citedOpen Access
Uridine induces differentiation in human neuroblastoma cells via Protein Kinase C epsilon
Journal of Neuroscience Research·2000· 16 cited
Phosphonate Inhibitors of Adamalysin II and Matrix Metalloproteinases
Annals of the New York Academy of Sciences·1999· 7 cited
Clinical Experiences with the Use of Indole-3-Pyruvic Acid
Advances in experimental medicine and biology·1999· 21 cited
Structures of adamalysin II with peptidic inhibitors. Implications for the design of tumor necrosis factor α convertase inhibitors
Protein Science·1998· 45 citedOpen Access
2 Å X‐ray structure of adamalysin II complexed with a peptide phosphonate inhibitor adopting a retro‐binding mode
FEBS Letters·1997· 38 cited
ADAMALYSIN II WITH PEPTIDOMIMETIC INHIBITOR POL656
1997
Processing of pro-tumour necrosis factor-α by venom metalloproteinases: a hypothesis towards explaining local tissue damage following snakebite
Toxicon·1997· 5 cited
Effect of exogenous inhibitors of matrix metalloproteinases on contact sensitivity to simple haptens
Immunology Letters·1997
Processing of pro‐tumor necrosis factor‐α by venom metalloproteinases: A hypothesis explaining local tissue damage following snake bite
European Journal of Immunology·1996· 146 cited
The use of synthetic peptides for the inhibition of snake venoms
Toxicon·1996
Antioxidant Properties of Indole-3-Pyruvic Acid
Advances in experimental medicine and biology·1996· 32 cited
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Frequent Co-authors

Silvana D’Alessio(7), G. De Luca(7), Gavin D. Laing(4), Giovanni Francesco Fasciglione(3), Stefano Marini(3), Massimo Coletta(3), Lawrence F. Kress(3), Carlo Gallina(3), M. V. Lavaggi(3), G. Di Stazio(3), Antonio Sella(3), Ana M. Moura‐da‐Silva(2), Mark J. I. Paine(2), Jeremy Michael Thomas Jonathan Dennison(2), Julian M. Crampton(2), F. Xavier Gomis‐Rüth(2), Giampiero De Sanctis(2), E. Gavuzzo(2), Cesare Giordano(2), B. Gorini(2)