John D. Lipscomb

University of Minnesota System — United States

Chemistry · Physical Sciences

76h-index19.1kcitations290works6.02yr avg
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Research Topics

Metal-Catalyzed Oxygenation Mechanisms(208), Microbial metabolism and enzyme function(76), Microbial bioremediation and biosurfactants(55), Photosynthetic Processes and Mechanisms(49), Metalloenzymes and iron-sulfur proteins(34)

Publications290 total

Nature of the Reactive Biferric Peroxy Intermediate P′ in the Arylamine Oxygenases and Related Binuclear Fe Enzymes
Journal of the American Chemical Society·2025· 4 citedOpen Access
Mechanistic Aspects of Dihydroxybenzoate Dioxygenases
Metal ions in biological systems·2024· 14 cited
Approaches to determination of the mechanism of the Rieske monooxygenase salicylate 5-hydroxylase
Methods in enzymology on CD-ROM/Methods in enzymology·2024
Nuclear Resonance Vibrational Spectroscopy Definition of Peroxy Intermediates in Catechol Dioxygenases: Factors that Determine Extra- versus Intradiol Cleavage
Journal of the American Chemical Society·2023· 8 citedOpen Access
Contrasting Mechanisms of Aromatic and Aryl-Methyl Substituent Hydroxylation by the Rieske Monooxygenase Salicylate 5-Hydroxylase
Biochemistry·2022· 8 citedOpen Access
Dynamic Long-Range Interactions Influence Substrate Binding and Catalysis by Human Histidine Triad Nucleotide-Binding Proteins (HINTs), Key Regulators of Multiple Cellular Processes and Activators of Antiviral ProTides
Biochemistry·2022· 2 citedOpen Access
Determination of the iron(IV) local spin states of the Q intermediate of soluble methane monooxygenase by Kβ X-ray emission spectroscopy
JBIC Journal of Biological Inorganic Chemistry·2022· 11 citedOpen Access
X-ray Crystal Structures of Methane Monooxygenase Hydroxylase Complexes with Variants of Its Regulatory Component: Correlations with Altered Reaction Cycle Dynamics
Biochemistry·2021· 5 citedOpen Access
Nuclear Resonance Vibrational Spectroscopic Definition of the Fe(IV)<sub>2</sub> Intermediate Q in Methane Monooxygenase and Its Reactivity
Journal of the American Chemical Society·2021· 43 citedOpen Access
Soluble Methane Monooxygenase Component Interactions Monitored by <sup>19</sup>F NMR
Biochemistry·2021· 13 citedOpen Access
Small molecule tunnels in metalloenzymes viewed as extensions of the active site
2021Open Access
Small-Molecule Tunnels in Metalloenzymes Viewed as Extensions of the Active Site
Accounts of Chemical Research·2021· 57 citedOpen Access
Complex structure of Methane monooxygenase hydroxylase and regulatory subunit with fluorosubstituted tryptophans
2021
<scp>6‐phenylpyrrolocytosine</scp> as a fluorescent probe to examine nucleotide flipping catalyzed by a <scp>DNA</scp> repair protein
Biopolymers·2020· 3 citedOpen Access
Reorganization of the diiron cluster active site of soluble methane monooxygenase by MMOB enforces specificity for methane as described by XFEL crystal structures of the sMMOH:MMOB complex
2020
Reorganization of the diiron cluster active site of soluble methane monooxygenase by MMOB enforces specificity for methane as described by XFEL crystal structures of the sMMOH:MMOB complex
2020
Reorganization of the diiron cluster active site of soluble methane monooxygenase by MMOB enforces specificity for methane as described by XFEL crystal structures of the sMMOH:MMOB complex
2020
Structural Studies of the <i>Methylosinus trichosporium</i> OB3b Soluble Methane Monooxygenase Hydroxylase and Regulatory Component Complex Reveal a Transient Substrate Tunnel
Biochemistry·2020· 31 citedOpen Access
High-Resolution XFEL Structure of the Soluble Methane Monooxygenase Hydroxylase Complex with its Regulatory Component at Ambient Temperature in Two Oxidation States
Journal of the American Chemical Society·2020· 65 citedOpen Access
Crystal Structure of Methylosinus trichosporium OB3b Soluble Methane Monooxygenase Hydroxylase and Regulatory Component Complex
2020
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Frequent Co-authors

Eckard Münck(11), Wayne A. Froland(6), Lawrence Que(5), Brian G. Fox(5), D.H. Ohlendorf(5), I. C. Gunsalus(5), Allen M. Orville(5), Elena G. Kovaleva(4), Jeremy C. Nesheim(4), R. Banerjee(3), Kristene K. Surerus(3), D.M. Arciero(3), Thomas A. Kent(3), Michael P. Hendrich(3), Peter G. Debrunner(3), Bradley J. Wallar(2), Lijin Shu(2), Lawrence P. Wackett(2), B G Fox(2), J E Dege(2)