Hongde Xu

Capital Medical University — China

Medicine · Health Sciences

19h-index1.1kcitations41works17.42yr avg
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Research Topics

Autophagy in Disease and Therapy(10), Sirtuins and Resveratrol in Medicine(9), Epigenetics and DNA Methylation(8), DNA Repair Mechanisms(6), Thyroid Disorders and Treatments(5)

Publications41 total

Editorial: Drug development for pancreatic cancer: novel targets, drug candidates and mechanisms
Frontiers in Oncology·2025Open Access
Mitochondrial ROS triggers mitophagy through activating the DNA damage response signaling pathway
Proceedings of the National Academy of Sciences·2025· 8 citedOpen Access
DNA damage response pathway regulates Nrf2 in response to oxidative stress
Science Advances·2025· 9 citedOpen Access
Tumor microenvironment-associated oxidative stress impairs SIRT1 secretion to suppress anti-tumor immune response
Cell Reports·2025· 4 citedOpen Access
A simple and effective method to enhance the level of gamma-aminobutyric acid in Chinese yam tubers while preserving its original appearance
Food Chemistry X·2025· 2 citedOpen Access
Unraveling the nexus between cellular senescence and malignant transformation: a paradigm shift in cancer research
Cancer Biology and Medicine·2024· 4 citedOpen Access
Insights on E1-like enzyme ATG7: functional regulation and relationships with aging-related diseases
Communications Biology·2024· 29 citedOpen Access
Dysfunction of Akt/FoxO3a/Atg7 regulatory loop magnifies obesity-regulated muscular mass decline
Molecular Metabolism·2024· 5 citedOpen Access
A novel role for the ROS-ATM-Chk2 axis mediated metabolic and cell cycle reprogramming in the M1 macrophage polarization
Redox Biology·2024· 96 citedOpen Access
Cooperative effects of <scp>SIRT1</scp> and <scp>SIRT2</scp> on <scp>APP</scp> acetylation
Aging Cell·2023· 15 citedOpen Access
De-ubiquitination of SAMHD1 by USP7 promotes DNA damage repair to overcome oncogenic stress and affect chemotherapy sensitivity
Oncogene·2023· 22 citedOpen Access
Progerin modulates the IGF-1R/Akt signaling involved in aging
Science Advances·2022· 25 citedOpen Access
Inhibition of SIRT2 promotes APP acetylation and ameliorates cognitive impairment in APP/PS1 transgenic mice
Cell Reports·2022· 51 citedOpen Access
The Role of Autophagy in Lamellar Body Formation and Surfactant Production in Type 2 Alveolar Epithelial Cells
International Journal of Biological Sciences·2022· 19 citedOpen Access
The deacetylation of Foxk2 by Sirt1 reduces chemosensitivity to cisplatin
Journal of Cellular and Molecular Medicine·2021· 12 citedOpen Access
De-ubiquitination of SAMHD1 by USP7 overcomes oncogenic stress and contributes to chemotherapy insensitivity
Research Square (Research Square)·2021Open Access
The deacetylation-phosphorylation regulation of SIRT2-SMC1A axis as a mechanism of antimitotic catastrophe in early tumorigenesis
Science Advances·2021· 38 citedOpen Access
The p62/Keap1/Nrf2 axis in the control of C-2 induced human gastric cancer cell death switching between autophagy and apoptosis
Research Square (Research Square)·2021Open Access
Post-Translational Modifications of PCNA in Control of DNA Synthesis and DNA Damage Tolerance-the Implications in Carcinogenesis
International Journal of Biological Sciences·2021· 47 citedOpen Access
The Regulatory Effect of SIRT1 on Extracellular Microenvironment Remodeling
International Journal of Biological Sciences·2020· 22 citedOpen Access
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Frequent Co-authors

Liu Cao(28), Xiaoyu Song(25), Qiqiang Guo(19), Wendong Guo(19), Fei Yi(16), Xiaoman Li(13), Jingwei Liu(13), Ning Bai(12), Tingting Zhou(11), Bo Jiang(10), Yi Guan(8), Yanling Feng(7), Xuan Wu(7), Mengtao Ma(6), Chunlu Li(6), Xiang Da Dong(6), Zhuo Wang(6), Yang Yu(6), Jian Gong(5), Jing Dong(5)