Joyce L. Barwick

Denver Health Medical Center — United States

Pharmacology, Toxicology and Pharmaceutics · Life Sciences

15h-index2.4kcitations15works0.02yr avg
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Research Topics

Pharmacogenetics and Drug Metabolism(12), Hormonal Regulation and Hypertension(5), Drug Transport and Resistance Mechanisms(4), Estrogen and related hormone effects(3), Receptor Mechanisms and Signaling(2)

Publications15 total

Identification of Genes Controlled by the Pregnane X Receptor by Microarray Analysis of mRNAs from Pregnenolone 16 -Carbonitrile-Treated Rats
Toxicological Sciences·2006· 45 citedOpen Access
Regulation of a xenobiotic sulfonation cascade by nuclear pregnane X receptor (PXR)
Proceedings of the National Academy of Sciences·2002· 278 citedOpen Access
Reciprocal activation of Xenobiotic response genes by nuclear receptors SXR/PXR and CAR
Genes & Development·2000· 508 citedOpen Access
Humanized xenobiotic response in mice expressing nuclear receptor SXR
Nature·2000· 656 cited
Characterization of DNA-Binding Proteins Required for Glucocorticoid Induction of CYP3A23
Archives of Biochemistry and Biophysics·1998· 17 cited
Trans-species gene transfer for analysis of glucocorticoid-inducible transcriptional activation of transiently expressed human CYP3A4 and rabbit CYP3A6 in primary cultures of adult rat and rabbit hepatocytes.
Molecular Pharmacology·1996· 138 cited
A Novel cis-Acting Element in a Liver Cytochrome P450 3A Gene Confers Synergistic Induction by Glucocorticoids plus Antiglucocorticoids
Journal of Biological Chemistry·1995· 84 citedOpen Access
Cloning of a cDNA coding for P-450 LM3c from rabbit liver microsomes and regulation of its expression
Nucleic Acids Research·1986· 32 citedOpen Access
Demonstration in multiple species of inducible hepatic cytochromes P-450 and their mRNAs related to the glucocorticoid-inducible cytochrome P-450 of the rat.
Molecular Pharmacology·1985· 199 cited
Induction of cytochrome P-450 by glucocorticoids in rat liver. I. Evidence that glucocorticoids and pregnenolone 16 alpha-carbonitrile regulate de novo synthesis of a common form of cytochrome P-450 in cultures of adult rat hepatocytes and in the liver in vivo.
Journal of Biological Chemistry·1984· 175 citedOpen Access
Immunochemical evidence for induction of a common form of hepatic cytochrome P-450 in rats treated with pregnenolone-16 alpha-carbonitrile or other steroidal or non-steroidal agents.
Molecular Pharmacology·1982· 133 cited
Measurement of the metabolism of cytochrome <i>P</i>-450 in cultured hepatocytes by a quantitative and specific immunochemical method
Biochemical Journal·1982· 31 citedOpen Access
Induction of cytochrome P-450 by pregnenolone-16 alpha-carbonitrile in primary monolayer cultures of adult rat hepatocytes and in a cell-free translation system.
Journal of Biological Chemistry·1981· 59 citedOpen Access
Inhibition by cycloheximide of degradation of cytochrome <i>P</i>-450 in primary cultures of adult rat liver parenchymal cells and <i>in vivo</i>
Biochemical Journal·1979· 17 citedOpen Access
Studies of rat liver microsomal diglyceride acyltransferase and cholinephosphotransferase using microsomal-bound substrate: effects of high fructose intake
Journal of Lipid Research·1975· 62 citedOpen Access

Frequent Co-authors

Philip S. Guzelian(14), Linda C. Quattrochi(4), Wen Xie(3), Ronald M. Evans(3), Nabil A. Elshourbagy(3), Cynthia M. Simon(2), Steven Wrighton(2), Erin G. Schuetz(2), Patrick Maurel(2), Heather T. Hartle(2), Charles B. Yockey(2), Michael Downes(1), Bruce Blumberg(1), Michael C. Nelson(1), Brent A. Neuschwander‐Tetri(1), Elizabeth M. Brunt(1), Alexis M. Pierce(1), Stephen Safe(1), Bruce Blumberg(1), Junichiro Sonoda(1)