G. Malojcic

Biochemistry, Genetics and Molecular Biology · Life Sciences

16h-index950citations47works0.02yr avg
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Research Topics

Sulfur Compounds in Biology(6), Bacterial Genetics and Biotechnology(5), Enzyme Catalysis and Immobilization(5), RNA and protein synthesis mechanisms(4), Analytical Chemistry and Chromatography(4)

Publications47 total

Fragment-based discovery reveals unprecedented ligandability and enables direct targeting of the melanoma oncogene MITF
Figshare·2026Open Access
Fragment-based discovery reveals unprecedented ligandability and enables direct targeting of the melanoma oncogene MITF
Figshare·2026Open Access
Fragment-based discovery enables direct targeting of the melanoma oncogene MITF
Repository for Publications and Research Data (ETH Zurich)·2025Open Access
Fragment-based discovery enables direct targeting of the melanoma oncogene MITF
Nature Communications·2025Open Access
Transplanted organoids empower human preclinical assessment of drug candidate for the clinic
Science Advances·2022· 25 citedOpen Access
Discovery and Optimization of Highly Selective Inhibitors of CDK5
Journal of Medicinal Chemistry·2022· 24 citedOpen Access
CCDC 2093192: Experimental Crystal Structure Determination
The Cambridge Structural Database·2021Open Access
Discovery of SY-5609: A Selective, Noncovalent Inhibitor of CDK7
Journal of Medicinal Chemistry·2021· 80 citedOpen Access
Compound Screening
Elsevier eBooks·2021
Structural basis of TRPC4 regulation by calmodulin and pharmacological agents
eLife·2020· 66 citedOpen Access
TRPC4 in complex with inhibitor GFB-8438
2020
TRPC4 in LMNG detergent
2020
Author response: Structural basis of TRPC4 regulation by calmodulin and pharmacological agents
2020· 1 citedOpen Access
Selective inhibition of CDK7 reveals high-confidence targets and new models for TFIIH function in transcription
Genes & Development·2020· 84 citedOpen Access
Structural basis of TRPC4 regulation by calmodulin and pharmacological agents
2020· 6 citedOpen Access
SO038A TRANSLATIONAL KIDNEY ORGANOID SYSTEM BOLSTERS HUMAN RELEVANCE OF CLINICAL DEVELOPMENT CANDIDATE
Nephrology Dialysis Transplantation·2020
A translational kidney organoid system bolsters human relevance of clinical development candidate
2019· 2 citedOpen Access
Discovery of a Potent and Selective TRPC5 Inhibitor, Efficacious in a Focal Segmental Glomerulosclerosis Model
ACS Medicinal Chemistry Letters·2019· 58 citedOpen Access
A Peptidomimetic Antibiotic Interacts with the Periplasmic Domain of LptD from <i>Pseudomonas aeruginosa</i>
ACS Chemical Biology·2018· 90 citedOpen Access
CHAPTER 3.1. Disulfide Bond Formation and Isomerization in <i>Escherichia coli</i>
Chemical biology·2018
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Frequent Co-authors

Rudi Glockshuber(19), Robin L. Owen(12), Mark W. Ledeboer(10), Maolin Yu(7), Maurice S. Brozzo(6), John P.A. Grimshaw(6), Daniel Kahne(5), Kristin B. Hamman(5), Shanhu Hu(5), Jason Marineau(5), Deivanayagabarathy Vinayagam(5), Dennis Quentin(5), Felipe Merino(5), Markus Stabrin(5), Oliver Hofnagel(5), Stefan Raunser(5), Xin-Ru Pan-Zhou(5), Jean-Christophe Harmange(5), Michael J. Bradley(4), Nan Rosemary Ke(4)