Klaus Ley

Augusta University — United States

Medicine · Health Sciences

137h-index77.0kcitations969works3.82yr avg
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Research Topics

Cell Adhesion Molecules Research(348), Atherosclerosis and Cardiovascular Diseases(200), Immune Response and Inflammation(107), Neutrophil, Myeloperoxidase and Oxidative Mechanisms(104), Platelet Disorders and Treatments(91)

Publications967 total

Cardiovascular Manifestations and Immunobiology of Sarcoidosis
Arteriosclerosis Thrombosis and Vascular Biology·2025
Lipid nanotubes unmask neutrophils for complement attack
Blood·2025Open Access
A CD25–chemokine receptor complex initiates noncanonical IL-2 signaling
Journal of Biological Chemistry·2025Open Access
Abstract 4370467: Downregulation of CCR6 in severe coronary artery disease impairs marginal zone B cell mediated atheroprotective IgM production
Circulation·2025
Neutrophil-specific CD18 deletion protect male but not female mice from myocardial ischemia-reperfusion injury 2039
The Journal of Immunology·2025Open Access
Co-inhibition of PD-1 and CD73 breaks tolerance of autoreactive CD4+ T cells in vivo 2362
The Journal of Immunology·2025
Defective autophagy drives the transition from regulatory Tregs to cytotoxic exTreg CD4+ T cells 3167
The Journal of Immunology·2025Open Access
Single-cell eQTL mapping in PBMCs reveals genes that modulate the immune response in atherosclerosis 3202
The Journal of Immunology·2025Open Access
Hyperinsulinemia promotes atherosclerosis by inducing metabolic reprogramming of autoreactive CD4+ T cells 2359
The Journal of Immunology·2025Open Access
Proinflammatory and cytotoxic CD38+HLA-DR+ effector memory CD8+ T cells are peripherally expanded in human cardiac allograft vasculopathy
American Journal of Transplantation·2025Open Access
ER stress induced mitochondrial dysfunction drives Treg instability in coronary artery disease
EMBO Molecular Medicine·2025· 2 citedOpen Access
Stage-resolved Spatial Multi-omics Reveals Myeloid Niches in Human Atherosclerotic Plaques
2025Open Access
The protective role of γδ T cells in endometrial cancer
Cancer Immunology Immunotherapy·2025Open Access
Functional unfolding of the integrin αX transmembrane helix
Proceedings of the National Academy of Sciences·2025· 1 citedOpen Access
Functional Role of Single-Nucleotide Polymorphisms on IFNG and IFNGR1 in Humans with Cardiovascular Disease
International Journal of Molecular Sciences·2025Open Access
Self-Reactive B Cells in Artery Tertiary Lymphoid Organs Encode Pathogenic High Affinity Autoantibody in Atherosclerosis
2025Open Access
Automated denoising of CITE-seq data with ThresholdR
Cell Reports Methods·2025Open Access
Loss of effector Treg signature in APOB-reactive CD4+ T cells in patients with coronary artery disease
Nature Cardiovascular Research·2025· 2 cited
RhoA GAP Myo9b regulates β2-integrin activity and neutrophil recruitment during murine acute kidney injury
Blood·2025· 3 cited
Cardiac sarcoidosis diagnosed 7 years after detection of ventricular tachycardia during pharmacologic stress testing
HeartRhythm Case Reports·2025Open Access
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Frequent Co-authors

Elena Galkina(6), Catherine C. Hedrick(6), Yuqing Huo(5), Holger Winkels(4), James K. Liao(3), Christian Weber(3), Clément Cochain(3), Dennis Wolf(3), Alma Zernecke(3), Alexander Zarbock(3), Eric J. Kunkel(3), Myron I. Cybulsky(2), Frédéric Geissmann(2), Steffen Jung(2), Marco Orecchioni(2), Yanal Ghosheh(2), Akula Bala Pramod(2), Tommaso Simoncini(2), Ali Hafezi‐Moghadam(2), Andreas Schober(2)