Wolfgang Wohlleben

German Center for Infection Research — Germany

Medicine · Health Sciences

59h-index14.1kcitations271works6.42yr avg
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Research Topics

Microbial Natural Products and Biosynthesis(163), Genomics and Phylogenetic Studies(81), Bacterial Genetics and Biotechnology(39), Carbohydrate Chemistry and Synthesis(35), RNA and protein synthesis mechanisms(29)

Publications270 total

Gene sco1417 encodes a positive regulator of the de novo biosynthesis of pyridoxal 5ʹ-phosphate (vitamin B6) in Streptomyces coelicolor M145
BMC Microbiology·2025Open Access
Unveiling the substrate specificity of the ABC transporter Tba and its role in glycopeptide biosynthesis
iScience·2025Open Access
GlnA3 <i> <sub>Mt</sub> </i> is able to glutamylate spermine but it is not essential for the detoxification of spermine in <i>Mycobacterium tuberculosis</i>
Journal of Bacteriology·2025· 4 citedOpen Access
CRISPR-Cas in actinomycetes: still a lot to be discovered
microLife·2025Open Access
Neuartige synthetische Wirkstoffe zur Tuberkulosebekämpfung
BIOspektrum·2024· 1 citedOpen Access
Generation of lysolipin derivatives by genetic engineering
Frontiers in Chemical Biology·2024· 3 citedOpen Access
Role of Carbon, Nitrogen, Phosphate and Sulfur Metabolism in Secondary Metabolism Precursor Supply in Streptomyces spp.
Microorganisms·2024· 39 citedOpen Access
Altering glycopeptide antibiotic biosynthesis through mutasynthesis allows incorporation of fluorinated phenylglycine residues
RSC Chemical Biology·2024· 4 citedOpen Access
GlnA3 <i> <sub>Mt</sub> </i> is able to glutamylate spermine but it is not essential for the detoxification of spermine in <i>Mycobacterium tuberculosis</i>
2023· 4 citedOpen Access
Metabolic engineering of the shikimate pathway in Amycolatopsis strains for optimized glycopeptide antibiotic production
Metabolic Engineering·2023· 11 cited
Faculty Opinions recommendation of A contractile injection system is required for developmentally regulated cell death in Streptomyces coelicolor.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2023
Faculty Opinions recommendation of Cytoplasmic contractile injection systems mediate cell death in Streptomyces.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2023
Optimization of FK-506 production in Streptomyces tsukubaensis by modulation of Crp-mediated regulation
Applied Microbiology and Biotechnology·2023· 9 citedOpen Access
Faculty Opinions recommendation of An interpretable machine learning approach to identify mechanism of action of antibiotics.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2023
A novel synthetic inhibitor of polyamine utilization in <i>Streptomyces coelicolor</i>
FEMS Microbiology Letters·2023· 4 citedOpen Access
A Whole-Cell Assay for Detection of Antibacterial Activity in Actinomycete Culture Supernatants
Methods in molecular biology·2022· 1 cited
Optimization of the precursor supply for an enhanced FK506 production in Streptomyces tsukubaensis
Frontiers in Bioengineering and Biotechnology·2022· 11 citedOpen Access
Buchrezension zu: Allgemeine Mikrobiologie
BIOspektrum·2022Open Access
Mechanism‐Based Design of the First GlnA4‐Specific Inhibitors
ChemBioChem·2022· 6 citedOpen Access
Genome Assembly and Genetic Traits of the Pleuromutilin-Producer Clitopilus passeckerianus DSM1602
Journal of Fungi·2022· 10 citedOpen Access
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Frequent Co-authors

Stefan Pelzer(15), Roderich D. Süßmuth(12), Daniel Bischoff(9), Tilmann Weber(8), Graeme Nicholson(7), Jens Reuther(6), Oliver Puk(6), Alfred Pühler(5), Bojan Bister(5), Yvonne Mast(5), Evi Stegmann(5), Günther Jung(5), Eriko Takano(4), Doris Hillemann(4), Jürgen Recktenwald(4), Eckhard Strauch(3), Günther Muth(3), Yvonne Tiffert(3), Volker Pfeifer(3), Sigrid Stockert(3)