Alexis Sloan

University of Miami — United States

Medicine · Health Sciences

16h-index4.0kcitations35works2.62yr avg
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Research Topics

Renal Diseases and Glomerulopathies(16), Fibroblast Growth Factor Research(6), Cell Adhesion Molecules Research(5), Parathyroid Disorders and Treatments(4), Cholesterol and Lipid Metabolism(4)

Publications34 total

Modulation of the Apolipoprotein M/S1PR4 Pathway Reduces Podocyte Lipid Overload in Alport Syndrome via Distinct Autophagy and Efflux Mechanisms
Journal of the American Society of Nephrology·2025
Nephrotic syndrome in mice elevates FGF23 levels and leads to cardiac hypertrophy in the absence of hyperphosphatemia
Nephrology Dialysis Transplantation·2025
Corrigendum to “Discoidin domain receptor 1 activation links extracellular matrix to podocyte lipotoxicity in Alport syndrome” eBioMedicine, Volume 63, January 2021, 103162
EBioMedicine·2025Open Access
The enzyme SMPDL3b in podocytes decouples proteinuria from chronic kidney disease progression in experimental Alport Syndrome
Kidney International·2025· 4 citedOpen Access
Ezetimibe Enhances Lipid Droplet and Mitochondria Contact Formation, Improving Fatty Acid Transfer and Reducing Lipotoxicity in Alport Syndrome Podocytes
International Journal of Molecular Sciences·2024· 10 citedOpen Access
Role of ATP Binding Cassette Subfamily A Member 1 (ABCA1) in Renal Toxicity
International Journal of Radiation Oncology*Biology*Physics·2024
Oxysterol-binding protein-like 7 deficiency leads to ER stress-mediated apoptosis in podocytes and proteinuria
American Journal of Physiology-Renal Physiology·2024· 4 citedOpen Access
ABCA1 deficiency contributes to podocyte pyroptosis priming via the APE1/IRF1 axis in diabetic kidney disease
Scientific Reports·2023· 16 citedOpen Access
ABCA1 Deficiency Primes Inflammasome via APE1/IRF1 Axis in Podocytes
Journal of the American Society of Nephrology·2022
Activation of Stimulator of IFN Genes (STING) Causes Proteinuria and Contributes to Glomerular Diseases
Journal of the American Society of Nephrology·2022· 71 citedOpen Access
FGF21-FGFR4 signaling in cardiac myocytes promotes concentric cardiac hypertrophy in mouse models of diabetes
Scientific Reports·2022· 22 citedOpen Access
FGF21-FGFR4 signaling in cardiac myocytes promotes concentric cardiac hypertrophy in mouse models of diabetes
2021· 1 citedOpen Access
Compounds targeting OSBPL7 increase ABCA1-dependent cholesterol efflux preserving kidney function in two models of kidney disease
Nature Communications·2021· 59 citedOpen Access
APOL1 risk variants affect podocyte lipid homeostasis and energy production in focal segmental glomerulosclerosis
Human Molecular Genetics·2021· 46 citedOpen Access
Discoidin domain receptor 1 activation links extracellular matrix to podocyte lipotoxicity in Alport syndrome
EBioMedicine·2020· 55 citedOpen Access
Modular Microphysiological System for Modeling of Biologic Barrier Function
Frontiers in Bioengineering and Biotechnology·2020· 30 citedOpen Access
Novel Small Molecule Inducers of ABCA1-Dependent Cholesterol Efflux Preserve Renal Function in Mouse Models of FSGS and Alport Syndrome
Journal of the American Society of Nephrology·2020
Discovery of a Small-Molecule Drug for Treating Diabetic Kidney Disease
Journal of the American Society of Nephrology·2020
ATP-binding cassette A1 deficiency causes cardiolipin-driven mitochondrial dysfunction in podocytes
Journal of Clinical Investigation·2019· 169 citedOpen Access
SMPDL3b modulates insulin receptor signaling in diabetic kidney disease
Nature Communications·2019· 95 citedOpen Access
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Frequent Co-authors

Alessia Fornoni(18), Sandra Merscher(17), Alla Mitrofanova(14), Christian Faul(13), Mengyuan Ge(11), Jin‐Ju Kim(11), Gloria Michelle Ducasa(10), Armando J. Mendez(10), Shamroop Kumar Mallela(9), Javier Varona Santos(9), Judith Molina(8), Dominik Kentrup(6), Alexander Grabner(6), George W. Burke(6), Karla Schramm(5), Christopher E. Pedigo(5), Judith Molina David(5), Christopher Yanucil(4), Matthias Kretzler(4), Xiaochen Liu(4)