Takao Iwawaki

Kanazawa Medical University — Japan

Biochemistry, Genetics and Molecular Biology · Life Sciences

50h-index9.7kcitations173works5.72yr avg
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Research Topics

Endoplasmic Reticulum Stress and Disease(103), Autophagy in Disease and Therapy(27), Pancreatic function and diabetes(19), RNA regulation and disease(19), Genomics, phytochemicals, and oxidative stress(12)

Publications172 total

Endothelial IRE1 signaling maintains blood–brain barrier integrity and limits neuroinflammation after traumatic brain injury
Cell Death and Disease·2026Open Access
Inositol-requiring enzyme 1 alpha is essential for dentinogenesis
Frontiers in Physiology·2025Open Access
Roles of vasopressin in renal blood flow and vascular resistance in male mice after treadmill running: A mechanism for <scp>ALPE</scp>
Physiological Reports·2025Open Access
Bardoxolone methyl (Bard)-mediated strong suppression of calcium oxalate crystal formation in renal crystal recurrence model
Scientific Reports·2025Open Access
Leukocyte-intrinsic ER stress responses contribute to chemotherapy-induced peripheral neuropathy
Science Translational Medicine·2025· 3 cited
The <scp>IRE1</scp> / <scp>XBP1s</scp> Axis Regulates Innate Immune Responses in Conventional Dendritic Cells During <scp>ZIKV</scp> Infection
The FASEB Journal·2025· 1 cited
PERK signaling maintains hematopoietic stem cell pool integrity under endoplasmic reticulum stress by promoting proliferation
Blood·2025· 5 citedOpen Access
IRE1α promotes phagosomal calcium flux to enhance macrophage fungicidal activity
Cell Reports·2025· 7 citedOpen Access
Rapid thawing enhances tissue destruction in a mouse model of cutaneous cryoablation: Insights into oxidative stress and neutrophil activation
Journal of Dermatological Science·2025Open Access
Characterization of FAM114A1: a novel podocyte cytoskeleton-associated protein upregulated in glomerular injury
American Journal of Physiology-Renal Physiology·2025· 1 citedOpen Access
PERK Signaling Maintains Hematopoietic Stem Cell Pool Integrity under Endoplasmic Reticulum Stress by Promoting Proliferation
2024· 1 citedOpen Access
PERK Maintains Hematopoietic Stem Cells Pool Integrity By Promoting Proliferation
Blood·2024Open Access
Therapeutic potential of 4-phenylbutyric acid against methylmercury-induced neuronal cell death in mice
Archives of Toxicology·2024· 1 citedOpen Access
High-grade serous ovarian cancer development and anti-PD-1 resistance is driven by IRE1α activity in neutrophils
OncoImmunology·2024· 14 citedOpen Access
Paneth cell TNF signaling induces gut bacterial translocation and sepsis
Cell Host & Microbe·2024· 18 citedOpen Access
High-grade serous ovarian cancer development and anti-PD-1 resistance is driven by IRE1α activity in neutrophils
2024· 2 citedOpen Access
Exposure to volatile ferroptosis inhibitor, TEMPO, reduced cutaneous ischemia-reperfusion injury progression to pressure ulcer formation in a mouse model
Journal of Dermatological Science·2024· 5 citedOpen Access
The IRE1α/XBP1 signaling axis drives myoblast fusion in adult skeletal muscle
EMBO Reports·2024· 12 citedOpen Access
Protein translation rate determines neocortical neuron fate
Nature Communications·2024· 20 citedOpen Access
Deletion of IRE1α in podocytes exacerbates diabetic nephropathy in mice
Scientific Reports·2024· 5 citedOpen Access
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Frequent Co-authors

Kenji Kohno(16), Ryoko Akai(6), Daisuke Oikawa(6), Michiko Saito(5), Yukio Kimata(4), Timon E. Adolph(3), Lukas Niederreiter(3), Markus Tschurtschenthaler(3), Magdalena B. Flak(3), Philip Rosenstiel(3), Arthur Kaser(3), Richard S. Blumberg(3), Akio Tsuru(3), Motoyoshi Endo(3), Yuichi Oike(3), Akira Hosoda(3), Ling Qi(3), Mio Tokuda(3), Michal Tomczak(2), Shuhei Hosomi(2)