Nafiseh Nafissi

Biochemistry, Genetics and Molecular Biology · Life Sciences

10h-index593citations29works0.52yr avg
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Research Topics

RNA Interference and Gene Delivery(9), CRISPR and Genetic Engineering(9), Bacteriophages and microbial interactions(8), Virus-based gene therapy research(7), Viral Infectious Diseases and Gene Expression in Insects(5)

Publications29 total

Ministring DNA (msDNA): a novel linear covalently-closed DNA with enhanced stability for gene and cell therapy applications
Scientific Reports·2025Open Access
Exploring alternatives to plasmid DNA for safer, higher quality gene therapy
Nucleic Acid Insights·2024
MINISTRING DNA (MSDNATM): MAXIMIZING QUALITY OF NOVEL DNA VECTORS
Cytotherapy·2024
Manufacturing DNA in E. coli yields higher-fidelity DNA than in vitro enzymatic synthesis
Molecular Therapy — Methods & Clinical Development·2024· 2 citedOpen Access
Manufacturing DNA in E. coli yields higher fidelity DNA than <i>in vitro</i> enzymatic synthesis
2023Open Access
Application of an electro elution system for direct purification of linear covalently closed DNA fragments
Journal of Chromatography B·2023· 1 cited
Advances in gene-based vaccine platforms to address the COVID-19 pandemic
Advanced Drug Delivery Reviews·2021· 98 citedOpen Access
Specific Systems for Evaluation
Experientia supplementum·2018
Production of Double-stranded DNA Ministrings
Journal of Visualized Experiments·2016· 5 cited
Production of Double-stranded DNA Ministrings
Journal of Visualized Experiments·2016· 9 citedOpen Access
Non-viral gene therapy: Gains and challenges of non-invasive administration methods
Journal of Controlled Release·2015· 231 cited
Structural schematic of conventional surfactants &amp; gemini surfactants (A), and chemical structure of 16-3-16 gemini surfactant (B).16-3-16 Properties: cmc = 0.026 mM&lt;sup&gt;32&lt;/sup&gt;, Krafft Temperature = 42°C &lt;sup&gt;39&lt;/sup&gt;.
Figshare·2015Open Access
Physical Characterization of Gemini Surfactant-Based Synthetic Vectors for the Delivery of Linear Covalently Closed (LCC) DNA Ministrings
PLoS ONE·2015· 11 citedOpen Access
Neuroprotective therapies in glaucoma: II. Genetic nanotechnology tools
Frontiers in Neuroscience·2015· 18 citedOpen Access
Neuroprotective therapies in glaucoma: I. Neurotrophic factor delivery
Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology·2015· 27 cited
Optimized production of a safe and efficient gene therapeutic vaccine versus HIV via a linear covalently closed DNA minivector
BMC Infectious Diseases·2014· 3 citedOpen Access
Optimization of a One-Step Heat-Inducible In Vivo Mini DNA Vector Production System
PLoS ONE·2014· 12 citedOpen Access
Bacteriophage recombination systems and biotechnical applications
Applied Microbiology and Biotechnology·2014· 41 cited
DNA Ministrings: Highly Safe and Effective Gene Delivery Vectors
Molecular Therapy — Nucleic Acids·2014· 35 citedOpen Access
Construction and Characterization of a Robust in vivo Technology for the Production of Superior DNA Vectors for Gene Therapy and Vaccination
UWSpace (University of Waterloo)·2013Open Access
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Frequent Co-authors

Roderick Slavcev(19), Shawn Wettig(5), Steven J. Hersch(5), Marianna Földvári(4), Chi Hong Sum(4), Shirley Wong(3), Tranum Kaur(3), Siddarth Chandrasekaran(3), Jamie Lam(3), Olla Wasfi(2), Reza Safaee(2), Peggy Lam(2), Steven Denniss(2), Mojtaba Karimipour(2), S. Chandrasekaran(2), Ding-Wen Chen(1), Daniella Calderon(1), Lokesh Narsineni(1), Amirreza Rafiee(1), Deborah Pushparajah(1)