Christopher T. Winkelmann

Takeda (United States) — United States

Medicine · Health Sciences

17h-index928citations53works3.32yr avg
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Research Topics

Medical Imaging Techniques and Applications(11), Radiopharmaceutical Chemistry and Applications(6), Bone health and osteoporosis research(5), PI3K/AKT/mTOR signaling in cancer(5), Estrogen and related hormone effects(4)

Publications52 total

Volumetric MRI of dorsal root ganglia as a biomarker for disease progression and response to AAV treatment in a mouse model of Fabry disease
PLoS ONE·2025Open Access
Three-Dimensional Vector MR Elastography for Evaluating Tissue Mechanical Heterogeneity to Assess Liver Disease Progression
Radiology·2025· 8 citedOpen Access
Radiosynthesis and in vivo evaluation of [18F]BEAN as a potential mitochondria-based PET biomarker for metabolic disorders
Bioorganic & Medicinal Chemistry Letters·2025Open Access
Longitudinal imaging of therapeutic enzyme expression after gene therapy for Fabry disease using positron emission tomography and the radiotracer [18F]AGAL
Molecular Therapy·2024· 5 citedOpen Access
Radiosynthesis and Early Evaluation of a Positron Emission Tomography Imaging Probe [18F]AGAL Targeting Alpha-Galactosidase A Enzyme for Fabry Disease
Molecules·2023· 2 citedOpen Access
Supplementary Figures 1-3, Tables 1-2 from Downregulation of Notch Pathway by a γ-Secretase Inhibitor Attenuates AKT/Mammalian Target of Rapamycin Signaling and Glucose Uptake in an ERBB2 Transgenic Breast Cancer Model
2023Open Access
Data from Downregulation of Notch Pathway by a γ-Secretase Inhibitor Attenuates AKT/Mammalian Target of Rapamycin Signaling and Glucose Uptake in an ERBB2 Transgenic Breast Cancer Model
2023Open Access
Data from Downregulation of Notch Pathway by a γ-Secretase Inhibitor Attenuates AKT/Mammalian Target of Rapamycin Signaling and Glucose Uptake in an ERBB2 Transgenic Breast Cancer Model
2023Open Access
Supplementary Figures 1-3, Tables 1-2 from Downregulation of Notch Pathway by a γ-Secretase Inhibitor Attenuates AKT/Mammalian Target of Rapamycin Signaling and Glucose Uptake in an ERBB2 Transgenic Breast Cancer Model
2023Open Access
Gene therapy for cross-correction of somatic organs and the CNS in mucopolysaccharidosis II in rodents and non-human primates
Molecular Therapy — Methods & Clinical Development·2023· 10 citedOpen Access
Disease pathology in the iduronate-2-sulfatase KO mouse: Opportunities for novel endpoints for second generation enzyme replacement strategies
Molecular Genetics and Metabolism·2023
In Vivo Small Animal Imaging: A Comparison to Gross and Histopathologic Observations in Animal Models
Elsevier eBooks·2021· 3 cited
Contributors
Elsevier eBooks·2021
Multiparametric magnetic resonance imaging/magnetic resonance elastography assesses progression and regression of steatosis, inflammation, and fibrosis in alcohol‐associated liver disease
Alcoholism Clinical and Experimental Research·2021· 7 citedOpen Access
fMRI study of the role of glutamate NMDA receptor in the olfactory processing in monkeys
PLoS ONE·2018· 9 citedOpen Access
Assessment of near-infrared fluorophores to study the biodistribution and tumor targeting of an IL13 receptor α2 antibody by fluorescence molecular tomography
Oncotarget·2017· 11 citedOpen Access
Abstract 2861: Dose-dependent tissue distribution and tumor targeting of Notch3-ADC using fluorescence molecular tomography imaging
Cancer Research·2017
fMRI study of the role of glutamate NMDA receptor in the olfactory adaptation in rats: Insights into cellular and molecular mechanisms of olfactory adaptation
NeuroImage·2017· 16 cited
Odanacatib, effects of 16-month treatment and discontinuation of therapy on bone mass, turnover and strength in the ovariectomized rabbit model of osteopenia
Bone·2016· 14 cited
Automatic pose correction for image-guided nonhuman primate brain surgery planning
Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE·2016· 4 cited
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Frequent Co-authors

L. David Wise(9), Raymond E. Gibson(7), Timothy J. Hoffman(6), Christopher Ware(6), Saverio Giampaoli(6), John F. Reilly(6), Jeffrey L. Evelhoch(6), Belma Dogdas(6), Jason M. Uslaner(6), Clay L. Efferson(5), Jennifer Tammam(5), Shailendra B. Patel(5), Giuseppe Mesiti(5), Carolyn A. Buser(5), Timothy J. Yeatman(5), Domenico Coppola(5), Christopher Winter(5), Edwin Clark(5), Giulio Draetta(5), Peter R. Strack(5)