Jason Centracchio

Brown University — United States

Medicine · Health Sciences

10h-index907citations20works0.02yr avg
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Research Topics

Cardiac electrophysiology and arrhythmias(7), Ion channel regulation and function(5), Liver physiology and pathology(5), Organ Transplantation Techniques and Outcomes(5), Receptor Mechanisms and Signaling(4)

Publications20 total

Short-Long Heart Rate Variation Increases Dispersion of Action Potential Duration in Long QT Type 2 Transgenic Rabbit Model
Scientific Reports·2019· 9 citedOpen Access
Redox modification of ryanodine receptors by mitochondria‐derived reactive oxygen species contributes to aberrant Ca<sup>2+</sup> handling in ageing rabbit hearts
The Journal of Physiology·2013· 130 citedOpen Access
Age‐associated attenuation of autophagy underlies ryanodine receptor hyperactivity
The FASEB Journal·2013
Redox Modification of Ryanodine Receptors underlies Abnormal Calcium Handling in Aging Rabbit Hearts
Biophysical Journal·2013Open Access
Abstract 15425: The Novel Late Sodium Current Blocker GS-458967 Suppresses Action Potential Duration Alternans and Early Afterdepolarization in a Transgenic Rabbit Model of Long Qt Syndrome Type 2
Circulation·2012
Estradiol promotes sudden cardiac death in transgenic long QT type 2 rabbits while progesterone is protective
Heart Rhythm·2012· 137 citedOpen Access
Pore mutants of HERG and KvLQT1 downregulate the reciprocal currents in stable cell lines
American Journal of Physiology-Heart and Circulatory Physiology·2010· 30 citedOpen Access
Transgenic LQT1 and LQT2 rabbits provide a new model for safety screening for IKr or IKs blocking propensity of drugs
Journal of Pharmacological and Toxicological Methods·2008· 4 cited
Mechanisms of cardiac arrhythmias and sudden death in transgenic rabbits with long QT syndrome
Journal of Clinical Investigation·2008· 216 citedOpen Access
Abstract 569: Selective Elimination of IKs and IKr in Transgenic Rabbit Models of LQT1 and LQT2
Circulation·2006
Abstract 569: Selective Elimination of I <sub>Ks</sub> and I <sub>Kr</sub> in Transgenic Rabbit Models of LQT1 and LQT2
Circulation·2006
Hepatocyte growth factor induces an endothelin-mediated decline in glomerular filtration rate
American Journal of Physiology-Renal Physiology·2004· 7 cited
Hepatocyte Growth Factor Ameliorates Renal Interstitial Inflammation in Rat Remnant Kidney by Modulating Tubular Expression of Macrophage Chemoattractant Protein-1 and RANTES
Journal of the American Society of Nephrology·2004· 113 cited
Hepatocyte growth factor ameliorates progression of interstitial fibrosis in rats with established renal injury
Kidney International·2004· 75 citedOpen Access
Hepatocyte Growth Factor Modulates Matrix Metalloproteinases and Plasminogen Activator/Plasmin Proteolytic Pathways in Progressive Renal Interstitial Fibrosis
Journal of the American Society of Nephrology·2003· 96 cited
Renal production of hepatocyte growth factor increases after unilateral nephrectomy in man
Transplantation Proceedings·2002· 2 cited
HEPATOCYTE GROWTH FACTOR BECOMES ELEVATED AFTER DONOR NEPHRECTOMY AND RENAL TRANSPLANTATION
Transplantation·1999
Effect of hypoxic exposure on Na<sup>+</sup>/H<sup>+</sup>antiport activity, isoform expression, and localization in endothelial cells
American Journal of Physiology-Lung Cellular and Molecular Physiology·1998· 29 cited
Expression of Na + /H + Exchanger Isoforms in Inner Segment of Inner Medullary Collecting Duct (IMCD 3 )
The Journal of Membrane Biology·1998· 24 cited
Constitutive Expression of HGF Modulates Renal Epithelial Cell Phenotype and Induces c-met and Fibronectin Expression
Experimental Cell Research·1998· 35 cited

Frequent Co-authors

Gideon Koren(10), Lance D. Dworkin(8), Xuwen Peng(7), Michael Brunner(5), Gong Xin Liu(5), Manfred Zehender(5), Lorraine Schofield(4), Malcolm Kirk(4), Leroy L. Cooper(4), Rujun Gong(4), Evelyn Tolbert(4), Katja E. Odening(3), Eduardo J. Folco(3), Naveed Rana(3), Radmila Terentyeva(3), Dmitry Terentyev(3), Abdalla Rifai(3), Ohad Ziv(2), Bum‐Rak Choi(2), Tammy Donahay(2)