Giulia Mearini

Universität Hamburg — Germany

Medicine · Health Sciences

26h-index2.5kcitations62works4.42yr avg
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Research Topics

Cardiomyopathy and Myosin Studies(40), Cardiovascular Effects of Exercise(14), Viral Infections and Immunology Research(12), Muscle Physiology and Disorders(8), Cardiac electrophysiology and arrhythmias(6)

Publications61 total

Generation of human induced pluripotent stem cell lines carrying a heterozygous and homozygous PRKD1 c.1774G > A genetic variant causing syndromic congenital defects
Stem Cell Research·2026Open Access
Next-Generation Percutaneous Catheter–Based Closed-Loop Perfusion Concept Enables High-Precision Organ Delivery of Advanced Therapies
JACC Basic to Translational Science·2025· 1 citedOpen Access
Perinatal death in pig models of hypertrophic cardiomyopathy carrying sarcomere pathogenic variants
Journal of Molecular and Cellular Cardiology Plus·2025Open Access
Chronic Activation of Tubulin Tyrosination Improves Heart Function
Circulation Research·2024· 20 citedOpen Access
Generation of a patient-specific hiPS cell line with heterozygous GNB2 mutation (UKMi003-A) causative for human sinus node dysfunction and a corresponding CRISPR/Cas9-corrected isogenic control (UKMi004-A)
Stem Cell Research·2024· 1 citedOpen Access
Abstract 12927: Impact of AAV- <i>MYBPC3</i> Gene Transfer on Heart Structure and Function in Human and Mouse Models of Hypertrophic Cardiomyopathy
Circulation·2023
The W101C KCNJ5 Mutation Induces Slower Pacing by Constitutively Active GIRK Channels in hiPSC-Derived Cardiomyocytes
International Journal of Molecular Sciences·2023· 5 citedOpen Access
Chronic activation of tubulin tyrosination in HCM mice and in human iPSC-engineered heart tissues improves heart function
2023· 2 citedOpen Access
<i>PITX2</i> Knockout Induces Key Findings of Electrical Remodeling as Seen in Persistent Atrial Fibrillation
Circulation Arrhythmia and Electrophysiology·2023· 27 citedOpen Access
Modelling aberrant microtubule De-/Tyrosination in HiPSC-derived engineered heart tissues
Journal of Molecular and Cellular Cardiology·2022
ACTN2 Mutant Causes Proteopathy in Human iPSC-Derived Cardiomyocytes
Cells·2022· 23 citedOpen Access
Disease modeling of a mutation in α‐actinin 2 guides clinical therapy in hypertrophic cardiomyopathy
EMBO Molecular Medicine·2022· 7 citedOpen Access
Piezo2 is not an indispensable mechanosensor in murine cardiomyocytes
Scientific Reports·2022· 9 citedOpen Access
<i>ACTN2</i> mutant causes proteopathy in human iPSC-derived cardiomyocytes
2021· 1 citedOpen Access
Generation of bi-allelic MYBPC3 truncating mutant and isogenic control from an iPSC line of a patient with hypertrophic cardiomyopathy
Stem Cell Research·2021· 7 citedOpen Access
The ubiquitin–proteasome system in cardiac dysfunction
UNC Libraries·2021Open Access
Atrogin-1 and MuRF1 regulate cardiac MyBP-C levels via different mechanisms
UNC Libraries·2020Open Access
Cell Banking of hiPSCs: A Practical Guide to Cryopreservation and Quality Control in Basic Research
Current Protocols in Stem Cell Biology·2020· 24 citedOpen Access
Investigation of ventricular arrhythmia mechanisms in hypertrophic cardiomyopathy in mice and men
Journal of Molecular and Cellular Cardiology·2020
Phosphomimetic cardiac myosin-binding protein C partially rescues a cardiomyopathy phenotype in murine engineered heart tissue
Scientific Reports·2019· 19 citedOpen Access
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Frequent Co-authors

Lucie Carrier(34), Thomas Eschenhagen(26), Elisabeth Krämer(20), Saskia Schlossarek(17), Maksymilian Prondzynski(9), Arne Hansen(9), Birgit Geertz(8), Ingke Braren(8), Sandra D. Laufer(8), Christiane Neuber(6), Marc D. Lemoine(6), Monica Patten(6), Jolanda van der Velden(6), Ingra Mannhardt(5), Aya Shibamiya(5), Florian Weinberger(5), Antonia T.L. Zech(5), Felix W. Friedrich(5), Charles Redwood(5), Julia Münch(5)