Andrea Haegebarth

Biochemistry, Genetics and Molecular Biology · Life Sciences

30h-index12.3kcitations84works0.02yr avg
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Research Topics

Cancer, Hypoxia, and Metabolism(21), PI3K/AKT/mTOR signaling in cancer(17), Epigenetics and DNA Methylation(11), Cancer-related Molecular Pathways(11), Biochemical and Molecular Research(10)

Publications84 total

Data from BAY 80-6946 Is a Highly Selective Intravenous PI3K Inhibitor with Potent p110α and p110δ Activities in Tumor Cell Lines and Xenograft Models
2023Open Access
Supplemental Materials and Methods, Supplementary Tables 1 through 3, Supplementary Figures 1 through 4 from BAY 80-6946 Is a Highly Selective Intravenous PI3K Inhibitor with Potent p110α and p110δ Activities in Tumor Cell Lines and Xenograft Models
2023Open Access
Supplemental Materials and Methods, Supplementary Tables 1 through 3, Supplementary Figures 1 through 4 from BAY 80-6946 Is a Highly Selective Intravenous PI3K Inhibitor with Potent p110α and p110δ Activities in Tumor Cell Lines and Xenograft Models
2023Open Access
Data from BAY 80-6946 Is a Highly Selective Intravenous PI3K Inhibitor with Potent p110α and p110δ Activities in Tumor Cell Lines and Xenograft Models
2023Open Access
Abstract 3588: Discovery of potent and selective CSNK1A1 inhibitors for solid tumor therapy
Cancer Research·2022· 1 cited
Discovery and Characterization of the Potent and Highly Selective 1,7-Naphthyridine-Based Inhibitors BAY-091 and BAY-297 of the Kinase PIP4K2A
Journal of Medicinal Chemistry·2021· 19 citedOpen Access
Degradation of CCNK/CDK12 is a druggable vulnerability of colorectal cancer
Cell Reports·2021· 86 citedOpen Access
Discovery of the SMYD3 Inhibitor BAY-6035 Using Thermal Shift Assay (TSA)-Based High-Throughput Screening
SLAS DISCOVERY·2021· 25 citedOpen Access
Synergistic activity of IDH1 inhibitor BAY1436032 with azacitidine in IDH1 mutant acute myeloid leukemia
Haematologica·2020· 36 citedOpen Access
SLC25A32 sustains cancer cell proliferation by regulating flavin adenine nucleotide (FAD) metabolism
Oncotarget·2020· 32 citedOpen Access
Characterization of the Menin-MLL Interaction as Therapeutic Cancer Target
Cancers·2020· 38 citedOpen Access
Efficacy of Chemotherapy, Phd-Inhibitor Molidustat or BRD4 Inhibitor JQ1 in Combination with Targeted Inhibition of Mutated IDH1 in Human AML In Vivo
Blood·2019
Metabolic pathway analyses identify proline biosynthesis pathway as a promoter of liver tumorigenesis
Journal of Hepatology·2019· 133 cited
Abstract 3599: BAY 2402234: Preclinical evaluation of a novel, selective dihydroorotate dehydrogenase (DHODH) inhibitor for the treatment of colorectal carcinomas
Molecular and Cellular Biology / Genetics·2019
Abstract 3597: BAY 2402234: Preclinical evaluation of a novel, selective dihydroorotate dehydrogenase (DHODH) inhibitor for the treatment of diffuse large B-cell lymphoma (DLBCL)
Molecular and Cellular Biology / Genetics·2019
Abstract 2: Discovery of BAY 2402234 by phenotypic screening: A human Dihydroorotate Dehydrogenase (DHODH) inhibitor in clinical trials for the treatment of myeloid malignancies
Cancer Chemistry·2019· 2 cited
Abstract 3599: BAY 2402234: Preclinical evaluation of a novel, selective dihydroorotate dehydrogenase (DHODH) inhibitor for the treatment of colorectal carcinomas
Cancer Research·2019
Abstract 2: Discovery of BAY 2402234 by phenotypic screening: A human Dihydroorotate Dehydrogenase (DHODH) inhibitor in clinical trials for the treatment of myeloid malignancies
Cancer Research·2019· 7 cited
Abstract 3597: BAY 2402234: Preclinical evaluation of a novel, selective dihydroorotate dehydrogenase (DHODH) inhibitor for the treatment of diffuse large B-cell lymphoma (DLBCL)
Cancer Research·2019· 1 cited
Functional diversity of inhibitors tackling the differentiation blockage of MLL-rearranged leukemia
Journal of Hematology & Oncology·2019· 32 citedOpen Access
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Frequent Co-authors

Hans Clevers(11), Marcus Bauser(11), Dominik Mumberg(10), Roland Neuhaus(9), Karl Ziegelbauer(8), Sven Christian(8), Ashley Eheim(7), Angela L. Tyner(7), Johan H. van Es(6), Stefan Gradl(6), Katja Zimmermann(6), Ralf Lesche(6), Detlef Stoeckigt(6), Martin Michels(6), Maaike van den Born(5), Holger Hess‐Stumpp(5), Wenjun Bie(5), Ulf Boemer(5), Nick Barker(4), Pekka Kujala(4)