Jashvant D. Unadkat

University of Washington — United States

Medicine · Health Sciences

75h-index15.8kcitations388works2.22yr avg
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Research Topics

Drug Transport and Resistance Mechanisms(168), Pharmacological Effects and Toxicity Studies(95), Pharmacogenetics and Drug Metabolism(66), HIV/AIDS drug development and treatment(58), Pregnancy and Medication Impact(54)

Publications388 total

Elucidating the role of ABC transporters in the placental efflux of (−)- Δ9-tetrahydrocannabinol (THC) using a cocktail of ABC transport inhibitors
Placenta·2025
Regulation of Renal Transporters by Pro-inflammatory Cytokines in Human Proximal Tubular Epithelial Cells: Identification of the Perpetrator and Mechanisms
2025Open Access
Effect of proinflammatory cytokines on intestinal drug transporters in human enteroid monolayers
Drug Metabolism and Disposition·2025· 1 cited
Rosuvastatin PBPK Modeling: Incorporating Liver Concentrations and Effects of Ethnicity, Genetic Polymorphisms, Lactone Formation, DDI and Pregnancy
CPT Pharmacometrics & Systems Pharmacology·2025Open Access
Regulation of expression and activity of hepatic transporters by pregnancy-related hormones in HepaRG cells
Drug Metabolism and Disposition·2025
Characterization of organic anion transporting polypeptide (OATP)1B1 and OATP1B3 humanized rat as a translational model to study the pharmacokinetics of OATP1B substrate drugs
Drug Metabolism and Disposition·2025
Does cannabidiol (CBD) or delta-9-tetrahydrocannabinol (THC) induce drug metabolizing enzymes in human hepatocytes?
Drug Metabolism and Pharmacokinetics·2025
ARE Δ9-tetrahydrocannabinol and its major metabolites substrates or inhibitors of the human hepatic and placental solute-carrier transporters?
Drug Metabolism and Pharmacokinetics·2025
Predicting in vivo cannabinoid-drug interactions mediated via inhibition of UDP-glucuronosyltransferases using in vitro studies and physiologically based pharmacokinetic modeling and simulations
Drug Metabolism and Disposition·2025· 2 cited
P87. Comparison of Intramedullary Screw Fixation, K-wires, and Plating for Fixation of Phalangeal Fractures: A Meta-Analysis
Plastic & Reconstructive Surgery Global Open·2025Open Access
Navigating the Spatial Landscape of Placental Nutrient and Xenobiotic Transport: Implications for Maternal-Fetal Crosstalk (Abstract ID: 166654)
Journal of Pharmacology and Experimental Therapeutics·2025
Identification of selective substrates and inhibitors of the major human renal uptake transporters
Drug Metabolism and Disposition·2025· 6 cited
Quantification and prediction of human fetal (-)-Δ9-tetrahydrocannabinol/(±)-11-OH-Δ9-tetrahydrocannabinol exposure during pregnancy to inform fetal cannabis toxicity
Nature Communications·2025· 6 citedOpen Access
Cannabidiol and Δ9-tetrahydrocannabinol induce drug-metabolizing enzymes, but not transporters, in human hepatocytes: Implications for predicting complex cannabinoid–drug interactions
Drug Metabolism and Disposition·2025· 4 cited
Completely Externalized Radial Artery-Fed Pseudoaneurysm with Associated Skin Erosion: A Case Report
Journal for Vascular Ultrasound·2024
Are Δ9-Tetrahydrocannabinol and Its Major Metabolites Substrates or Inhibitors of Placental or Human Hepatic Drug Solute-Carrier Transporters?
International Journal of Molecular Sciences·2024· 2 citedOpen Access
Are Δ9-Tetrahydrocannabinol and Its Major Metabolites Substrates or Inhibitors of Placental or Human Hepatic Drug Solute-Carrier Transporters?
Preprints.org·2024Open Access
The effect of pregnancy-related hormones on hepatic transporters: studies with premenopausal human hepatocytes
Frontiers in Pharmacology·2024· 6 citedOpen Access
Dysregulation of Human Hepatic Drug Transporters by Proinflammatory Cytokines
Journal of Pharmacology and Experimental Therapeutics·2024· 14 citedOpen Access
Second Toe-to-thumb Transfer Using Intramedullary Screw Fixation after Traumatic Thumb Amputation
Plastic & Reconstructive Surgery Global Open·2024· 2 citedOpen Access
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Frequent Co-authors

Qingcheng Mao(7), Yurong Lai(7), Bhagwat Prasad(7), Anshul Gupta(7), Mary F. Hébert(5), Xiaoyan Chu(5), Kenneth E. Thummel(5), Rajgopal Govindarajan(5), Raymond Evers(4), Cornelis E. C. A. Hop(4), Laurent Salphati(4), Lin Zhou(4), Yi Zhang(3), Peng Hsiao(3), Honggang Wang(3), R. Robert Vethanayagam(3), Chung‐Ming Tse(3), Lucy Sasongko(2), Steve Shoner(2), DB Carr(2)