Jason W. Griffith

Massachusetts General Hospital — United States

Environmental Science · Physical Sciences

21h-index4.0kcitations64works1.32yr avg
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Research Topics

Water Quality and Resources Studies(19), Archaeology and Natural History(9), Immune Cell Function and Interaction(8), Asthma and respiratory diseases(7), IL-33, ST2, and ILC Pathways(6)

Publications64 total

Abstract 4370048: Aging-Associated Lymphatic Dysfunction Drives Cardiac Injury During Chronic H1N1 Infection
Circulation·2025
Endothelial ActRIIA inhibition protects the cardiac microvasculature in severe viral respiratory infection
2025Open Access
No bones about it: regulatory T cells promote fracture healing
Journal of Clinical Investigation·2025· 5 citedOpen Access
Interferon Gamma Signaling Skews Regulatory T-cells to a T-helper 1-like Phenotype and Impairs Their Ability to Suppress Immune Responses to Allergen
2024
Regulatory T cell-derived IL-1Ra suppresses the innate response to respiratory viral infection
Nature Immunology·2023· 28 citedOpen Access
Augmentation of Endothelial S1PR1 Attenuates Postviral Pulmonary Fibrosis
American Journal of Respiratory Cell and Molecular Biology·2023· 5 citedOpen Access
Differences in Ventilation Defects (VDefs) and Inflammatory Responses to Segmental Allergen Challenge Between Allergic Adults With and Without Asthma
2022
Notch4 signaling limits regulatory T-cell-mediated tissue repair and promotes severe lung inflammation in viral infections
Immunity·2021· 119 citedOpen Access
The receptor TREML4 amplifies TLR7-mediated signaling during antiviral responses and autoimmunity
UNC Libraries·2020Open Access
Lung Histopathology in Coronavirus Disease 2019 as Compared With Severe Acute Respiratory Sydrome and H1N1 Influenza
CHEST Journal·2020· 179 citedOpen Access
Interleukin-33 activates regulatory T cells to suppress innate γδ T cell responses in the lung
Nature Immunology·2020· 99 citedOpen Access
Lung parenchymal and airway changes on CT imaging following allergen challenge and bronchoalveolar lavage in atopic and asthmatic subjects
Annals of Translational Medicine·2020· 7 citedOpen Access
Loss of Endothelial S1PR1 Exacerbates Bleomycin-Induced Pulmonary Fibrosis Through Intra-Alveolar Coagulation and Immune Cell Infiltration
2020· 1 cited
Allergic asthma is distinguished by sensitivity of allergen-specific CD4+ T cells and airway structural cells to type 2 inflammation
UNC Libraries·2020· 4 citedOpen Access
Potentiometric surfaces, 2011–12, and water-level differences between 1995 and 2011–12, in wells of the “200-foot,” “500-foot,” and “700-foot” sands of the Lake Charles area, southwestern Louisiana
Scientific investigations map·2020Open Access
Migratory DCs activate TGF-β to precondition naïve CD8 <sup>+</sup> T cells for tissue-resident memory fate
Science·2019· 200 citedOpen Access
Peroxidase Sensitive Amplifiable Probe for Molecular Magnetic Resonance Imaging of Pulmonary Inflammation
ACS Sensors·2019· 28 citedOpen Access
Regulatory T Cell Subsets Differentially Regulate the Immune Response to Influenza
2019
The Pulmonary Endothelium Plays a Critical Role in the Fibrotic Response to Lung Injury Through S1PR1 and ROCK Mediated Cytoskeletal Rearrangements
2019· 1 cited
Airway Dendritic Cells in Allergic Asthmatics Respond to Allergen via Differential Expression of Tolerogenic and Innate Sensing Genes
2019
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Frequent Co-authors

Andrew D. Luster(13), Benjamin D. Medoff(10), Lawrence B. Prakken(7), Christina Schofield(6), John K. Lovelace(6), Robert B. Fendick(6), Richard Bucala(5), Lida P. Hariri(5), Daniel L. Hamilos(5), Lin Leng(4), David C. Adams(4), R. Scott Harris(4), Melissa J. Suter(4), Lucas Faustino(4), Rachel S. Knipe(4), Courtney McDonald(3), Philip E. Thuma(3), Victor R. Gordeuk(3), Robert A. Mitchell(3), Clemens K. Probst(3)