Klaudia Brix

University of Bremen — Germany

Medicine · Health Sciences

36h-index4.9kcitations157works0.42yr avg
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Research Topics

Thyroid Disorders and Treatments(44), Protease and Inhibitor Mechanisms(29), Growth Hormone and Insulin-like Growth Factors(15), Cellular transport and secretion(13), Erythrocyte Function and Pathophysiology(12)

Publications157 total

CU Cilia – an application for image analysis by machine learning – reveals significance of cysteine cathepsin K activity for primary cilia of human thyroid epithelial cells
Frontiers in Endocrinology·2025Open Access
Human tissue kallikrein 14 induces the expression of <scp>IL</scp> ‐6, <scp>IL</scp> ‐8, and <scp>CXCL1</scp> in skin fibroblasts through protease‐activated receptor 1 signaling
FEBS Journal·2025· 2 citedOpen Access
Topography‐Mediated Induction of Epithelial Mesenchymal Transition via Alumina Textiles for Potential Wound Healing Applications
Journal of Biomedical Materials Research Part A·2024Open Access
ProteoCure: A European network to fine-tune the proteome
Biochimie·2024Open Access
Cytoskeletal β-tubulin and cysteine cathepsin L deregulation by SARS-CoV-2 spike protein interaction with the neuronal model cell line SH-SY5Y
Biochimie·2024Open Access
Cathepsin V regulates cell cycle progression and histone stability in the nucleus of breast cancer cells
Frontiers in Pharmacology·2023· 15 citedOpen Access
Metallacarborane Cluster Anions of the Cobalt Bisdicarbollide-Type as Chaotropic Carriers for Transmembrane and Intracellular Delivery of Cationic Peptides
Journal of the American Chemical Society·2023· 42 citedOpen Access
Investigations on Primary Cilia of Nthy-ori 3-1 Cells upon Cysteine Cathepsin Inhibition or Thyrotropin Stimulation
International Journal of Molecular Sciences·2023· 5 citedOpen Access
Lack of L-type amino acid transporter 2 in murine thyroid tissue induces autophagy
Journal of Molecular Endocrinology·2022
Characterization of Cysteine Cathepsin Expression in the Central Nervous System of Aged Wild-Type and Cathepsin-Deficient Mice
Applied Sciences·2022Open Access
Trafficking of Full-Length and N-Terminally Truncated Cathepsin B in Human Colorectal Carcinoma Cells
Applied Sciences·2021· 4 citedOpen Access
Age-dependent response to T4 overtreatment and recovery on systemic and organ level
Journal of Molecular Endocrinology·2021· 1 cited
Trace Amine-Associated Receptor 1 Trafficking to Cilia of Thyroid Epithelial Cells
Cells·2021· 10 citedOpen Access
The Amino Acid Transporter Mct10/Tat1 Is Important to Maintain the TSH Receptor at Its Canonical Basolateral Localization and Assures Regular Turnover of Thyroid Follicle Cells in Male Mice
International Journal of Molecular Sciences·2021· 2 citedOpen Access
Monocarboxylate transporter 8 deficiency leads to autophagy-induced persistent cathepsin-mediated thyroglobulin processing triggered by insufficient L-type amino acid transporter 2 functionality
Endocrine Abstracts·2021
Role of Kallikrein 7 in Body Weight and Fat Mass Regulation
Biomedicines·2021· 16 citedOpen Access
The Thyroid Hormone Transporter Mct8 Restricts Cathepsin-Mediated Thyroglobulin Processing in Male Mice through Thyroid Auto-Regulatory Mechanisms That Encompass Autophagy
International Journal of Molecular Sciences·2021· 9 citedOpen Access
Procathepsin V Is Secreted in a TSH Regulated Manner from Human Thyroid Epithelial Cells and Is Accessible to an Activity-Based Probe
International Journal of Molecular Sciences·2020· 5 citedOpen Access
Significance of nuclear cathepsin V in normal thyroid epithelial and carcinoma cells
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research·2020· 28 cited
Constitutive activation of Nrf2 antioxidant pathway leads to age-dependent goiter and compensated hypothyroidism in mice
Endocrine Abstracts·2020
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Frequent Co-authors

Volker Herzog(10), Maren Rehders(8), Mads H. Haugen(5), Dagmar Führer(5), Josef Köhrle(5), Silvia Jordans(4), Carmen Tepel(4), Martin Linke(4), Gunhild M. Mælandsmo(4), Paul Säftig(3), Sofia Tedelind(3), Solveig Pettersen(3), Kjersti Flatmark(3), Tripti Tamhane(3), Heike Biebermann(3), Alaa Al-Hashimi(3), Maria Qatato(3), Ahmed Rezk(3), Hartwig Schepker(3), Matthias S. Ullrich(3)