Lars Hvass

University of Copenhagen — Denmark

Chemistry · Physical Sciences

7h-index285citations34works2.22yr avg
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Research Topics

Click Chemistry and Applications(18), Radiopharmaceutical Chemistry and Applications(14), Monoclonal and Polyclonal Antibodies Research(10), Advanced biosensing and bioanalysis techniques(5), Medical Imaging Techniques and Applications(5)

Publications34 total

Pretargeted Immuno-PET Enables Monoclonal Antibody Imaging Beyond the Blood–Brain Barrier
Molecular Pharmaceutics·2025Open Access
Brain Pretargeted PET – New Horizons to Image CNS Targets with Monoclonal Antibodies
Nuclear Medicine and Biology·2025
Development of a stable pretargeting platform for immuno-PET imaging
Nuclear Medicine and Biology·2025Open Access
Comparison of Organometallics Towards Electrophilic Aromatic 211At-Astatinations of Tetrazines and Application in Pretargeted Therapy
Nuclear Medicine and Biology·2025Open Access
Synthesis and in vivo evaluation of a polar [18F]BODIPY-Tetrazine as a pretargeted bimodal imaging agent
Applied Radiation and Isotopes·2025Open Access
Abstract 592: Theranostic 68Ga/131I compounds for PSMA targeted radioligand therapy
Cancer Research·2025
Head-to-Head Comparison of the <i>in Vivo</i> Performance of Highly Reactive and Polar <sup>18</sup>F-Labeled Tetrazines
Molecular Pharmaceutics·2025Open Access
An <sup>211</sup>At-labeled Tetrazine for Pretargeted Therapy
Journal of Medicinal Chemistry·2025· 3 cited
Advancing Antibody-Based Pretargeted PET Imaging of Protein Aggregates in the Brain
Research at the University of Copenhagen (University of Copenhagen)·2025
Brain Pretargeted PET – New Horizons to Image CNS Targets with Monoclonal Antibodies
2024· 2 citedOpen Access
Development of Polar BODIPY-Tetrazines for Rapid Pretargeted Fluorescence Imaging
ACS Omega·2024· 3 citedOpen Access
[68Ga]Ga-DOTAGA-Glu(FAPi)2 Shows Enhanced Tumor Uptake and Theranostic Potential in Preclinical PET Imaging
Diagnostics·2024· 1 citedOpen Access
Abstract 6034: PSMA targeted alpha radiopharmaceutical [211At]PSAt-3 inhibits tumor growth in a preclinical model of prostate cancer
Cancer Research·2024
Development and Preclinical Evaluation of [<sup>211</sup>At]PSAt-3-Ga: An Inhibitor for Targeted α-Therapy of Prostate Cancer
Journal of Nuclear Medicine·2024· 22 citedOpen Access
Development of BODIPY-Tetrazines as Pretargeted Bimodal Fluorescent-Radioactive Tracers
Nuclear Medicine and Biology·2023
Development of five Polar and Highly Reactive Tetrazines for Pretargeted Imaging
Nuclear Medicine and Biology·2023
Synthesis and radiolabeling of a polar [<sup>125</sup>I]I‐1,2,4,5‐tetrazine
Journal of Labelled Compounds and Radiopharmaceuticals·2022· 4 citedOpen Access
Synthesis and in vivo evaluation of [11C]tucatinib for HER2-targeted PET imaging
Bioorganic & Medicinal Chemistry Letters·2022· 7 citedOpen Access
Bioorthogonal Click of Colloidal Gold Nanoparticles to Antibodies In vivo
Chemistry - A European Journal·2022· 11 citedOpen Access
Extracorporeal clearing traps based on tetrazine ligation for pretargeted therapy and diagnostics
Nuclear Medicine and Biology·2022
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Frequent Co-authors

Matthias M. Herth(34), Andreas Kjær(33), Vladimir Shalgunov(29), Umberto Maria Battisti(28), Jesper Tranekjær Jørgensen(23), Rocío García‐Vázquez(14), Hannes Mikula(11), Christian B. M. Poulie(10), Klas Bratteby(9), Marius Müller(8), Dennis Svatunek(7), Jesper L. Kristensen(7), Tobias Gustavsson(7), Markus Staudt(6), Ida Nymann Petersen(5), Anne Skovsbo Clausen(5), Sture Lindegren(4), Holger Jensen(4), Andreas I. Jensen(4), Thomas Kustermann(4)