Takemitsu Nagahata

Nippon Kayaku (Japan) — Japan

Medicine · Health Sciences

16h-index1.1kcitations28works0.02yr avg
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Research Topics

Hepatitis B Virus Studies(6), HIV/AIDS drug development and treatment(5), Carbohydrate Chemistry and Synthesis(4), Wnt/β-catenin signaling in development and cancer(3), Cancer Genomics and Diagnostics(3)

Publications28 total

Sequence-dependent combination effect of NK012, a novel micellar nanoparticle of SN-38, with 5-fluorouracil in mouse colon cancer model.
Cancer Research·2008
Upregulation and Overexpression of <i>DVL1</i>, the Human Counterpart of the <i>Drosophila</i> Dishevelled Gene, in Prostate Cancer
Tumori Journal·2005· 48 cited
Identification of RAI3 as a therapeutic target for breast cancer
Endocrine Related Cancer·2005· 50 citedOpen Access
Up-regulation of CC chemokine, CCL3L1, and receptors, CCR3, CCR5 in human glioblastoma that promotes cell growth
Journal of Neuro-Oncology·2004· 61 cited
Gene expression patterns as marker for 5-year postoperative prognosis of primary breast cancers
Journal of Cancer Research and Clinical Oncology·2004· 18 citedOpen Access
Amplification, up-regulation and over-expression of C3G (CRK SH3 domain-binding guanine nucleotide-releasing factor) in non-small cell lung cancers
Journal of Human Genetics·2004· 44 citedOpen Access
Characterization of liver-cirrhosis nodules by analysis of gene-expression profiles and patterns of allelic loss
Journal of Human Genetics·2004· 13 citedOpen Access
Expression profiling to predict postoperative prognosis for estrogen receptor‐negative breast cancers by analysis of 25,344 genes on a cDNA microarray
Cancer Science·2004· 120 citedOpen Access
Upregulation and overexpression of human x-box binding protein 1 (hXBP-1) gene in primary breast cancers
Breast Cancer·2003· 88 cited
Up-regulation and overproduction of DVL-1, the human counterpart of the Drosophila dishevelled gene, in cervical squamous cell carcinoma
Oncology Reports·2003· 77 cited
Amplification, up‐regulation and over‐expression of <i>DVL‐1</i>, the human counterpart of the <i>Drosophila disheveled</i> gene, in primary breast cancers
Cancer Science·2003· 117 citedOpen Access
Comprehensive gene expression analysis of human NK cells and CD8+ T lymphocytes
International Immunology·2002· 109 citedOpen Access
Correlation of allelic losses and clinicopathological factors in 504 primary breast cancers
Breast Cancer·2002· 34 cited
Molecular Diagnosis for Breast Cancer
2002· 3 cited
ChemInform Abstract: Enantiomerically Pure Synthesis and Antiviral Evaluation of ((2′S,3′S)‐ Bis(hydroxymethyl)azetidin‐1‐yl)purine Nucleosides: Analogues of Oxetanocin‐A.
ChemInform·1996
Enantiomerically pure synthesis and antiviral evaluation of [(2′S, 3′S)-bis(hydroxymethyl)azetidin-1-yl] purine nucleosides: Analogs of oxetanocin-A
Bioorganic & Medicinal Chemistry Letters·1995· 14 cited
Pharmacokinetics and Biologic Activities of Human Native and Asialointerferon-βs
Journal of Interferon & Cytokine Research·1995· 16 cited
ChemInform Abstract: Nucleosides and Nucleotides. Part 132. Synthesis and Biological Evaluations of Ring‐Expanded Oxetanocin Analogues: Purine and Pyrimidine Analogues of 1,4‐Anhydro‐2‐deoxy‐D‐arabitol and 1,4‐Anhydro‐ 2‐deoxy‐3‐hydroxymethyl‐D‐arabitol.
ChemInform·1995· 3 cited
Carbohydrate‐Dependent Biological Activities of Glycosylated Human Interferon‐β on Human Hepatoblastoma Cells <i>In Vitro</i>
Microbiology and Immunology·1995· 10 citedOpen Access
Nucleosides and nucleotides. 132. Synthesis and biological evaluations of ring-expanded oxetanocin analogues: Purine and pyrimidine analogues of 1,4-anhydro-2-deoxy-d-arabitol and 1,4-anhydro-2-deoxy-3-hydroxymethyl-d-arabitol
Tetrahedron·1994· 58 cited
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Frequent Co-authors

Mitsuru Emi(11), Masamitsu Onda(8), Hisaki Nagai(8), Takashi Fujimoto(3), Futoshi Akiyama(3), Goi Sakamoto(3), Fujio Kasumi(3), Enjing Jin(3), Oichi Kawanami(3), Keiji Ueda(3), Osamu Chisaka(3), Akira Hirano(2), Kiyohiro Nishikawa(2), Yoshio Miki(2), Toshihiro Tanaka(2), Tatsuhiko Tsunoda(2), Akima Harada(2), Shoko Kawamoto(2), Toshiki Tsurimoto(2), Keiko Okino(2)