W. Sue T. Griffin

Central Arkansas Veterans Healthcare System — United States

Medicine · Health Sciences

65h-index17.4kcitations173works3.12yr avg
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Research Topics

Alzheimer's disease research and treatments(86), Neuroinflammation and Neurodegeneration Mechanisms(52), S100 Proteins and Annexins(45), Neuroscience and Neuropharmacology Research(13), Tryptophan and brain disorders(12)

Publications173 total

Cellular features of graft vs host disease prophylaxis impact on CD4 T cell reconstitution post allo-HCT
Blood·2025
Relief Well Sustainment Deployable Resilient Installation Water Purification and Treatment System (RWS-DRIPS) : treatment of relief wells at Perry Dam, Kansas
2025Open Access
When Two Worlds Collide: The Contribution and Association Between Genetics (APOEε4) and Neuroinflammation (IL-1β) in Alzheimer’s Neuropathogenesis
Cells·2025· 1 citedOpen Access
The Seminal Role of the Proinflammatory Cytokine IL-1β and Its Signaling Cascade in Glioblastoma Pathogenesis and the Therapeutic Effect of Interleukin-1β Receptor Antagonist (IL-1RA) and Tolcapone
International Journal of Molecular Sciences·2025· 2 citedOpen Access
Altered protein homeostasis in cardiovascular diseases contributes to Alzheimer’s-like neuropathology
Basic Research in Cardiology·2025Open Access
Abstract LB131: The role of the proinflammatory cytokine IL-1β and its signaling cascade in glioblastoma pathogenesis and the therapeutic effect of IL-1RA and Tolcapone as anticancer agents
Cancer Research·2025· 1 cited
Rescue of ApoE4-related lysosomal autophagic failure in Alzheimer’s disease by targeted small molecules
Communications Biology·2024· 18 citedOpen Access
Porphyromonas gingivalis Outer Membrane Vesicles as the Major Driver of and Explanation for Neuropathogenesis, the Cholinergic Hypothesis, Iron Dyshomeostasis, and Salivary Lactoferrin in Alzheimer’s Disease
Journal of Alzheimer s Disease·2021· 56 citedOpen Access
Glial Fibrillary Acidic Protein: A Biomarker and Drug Target for Alzheimer's Disease
SSRN Electronic Journal·2021· 1 citedOpen Access
Referee report. For: Recruiting the innate immune system with GM-CSF to fight viral diseases, including West Nile Virus encephalitis and COVID-19 [version 1; peer review: 1 approved, 1 approved with reservations]
Faculty of 1000 Research Ltd·2020Open Access
Interleukin-1β drives NEDD8 nuclear-to-cytoplasmic translocation, fostering parkin activation via NEDD8 binding to the P-ubiquitin activating site
Journal of Neuroinflammation·2019· 29 citedOpen Access
A probe in the connection between inflammation, cognition and suicide
Journal of Psychopharmacology·2018· 28 citedOpen Access
Microbes and Alzheimer's Disease
Americanae (AECID Library)·2017· 23 citedOpen Access
Referee report. For: Midlife interventions are critical in prevention, delay, or improvement of Alzheimer’s disease and vascular cognitive impairment and dementia [version 1; referees: 1 approved]
Faculty of 1000 Research Ltd·2017Open Access
Proteins that mediate protein aggregation and cytotoxicity distinguish Alzheimer's hippocampus from normal controls
Aging Cell·2016· 79 citedOpen Access
Microbes and Alzheimer’s Disease
Journal of Alzheimer s Disease·2016· 519 citedOpen Access
Referee report. For: Predictors of psychiatric rehospitalization among elderly patients [version 1; referees: 2 approved]
Faculty of 1000 Research Ltd·2016Open Access
Aging, Alzheimer's, and APOE genotype influence the expression and neuronal distribution patterns of microtubule motor protein dynactin-P50
Frontiers in Cellular Neuroscience·2015· 25 citedOpen Access
Frontotemporal lobar degeneration FTLD-tau: preclinical lesions, vascular, and Alzheimer-related co-pathologies
Journal of Neural Transmission·2015· 65 citedOpen Access
Alzheimer’s is associated with neuropathological changes in olfactory bulb that are related to <i>APOE</i> genotype (728.1)
The FASEB Journal·2014
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Frequent Co-authors

Robert E. Mrak(24), Jin G. Sheng(19), Steven W. Barger(8), Linda J. Van Eldik(8), David I. Graham(7), Robert E. Mrak(5), Yuekui Li(5), Steve Gentleman(3), Gareth W. Roberts(3), Ling Liu(3), James A. R. Nicoll(3), Cynthia R. Rovnaghi(3), Stephen M. Gentleman(3), Richard A. Jones(3), Laura Stanley(2), Heiko Braak(2), Federico Licastro(2), Lilian S. Murray(2), Dietmar Rudolf Thal(2), Pascale D. Leclercq(2)