William J. Jusko

University at Buffalo, State University of New York — United States

Pharmacology, Toxicology and Pharmaceutics · Life Sciences

72h-index23.8kcitations618works1.22yr avg
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Research Topics

Pharmacogenetics and Drug Metabolism(101), Antibiotics Pharmacokinetics and Efficacy(71), Analytical Methods in Pharmaceuticals(49), Drug Transport and Resistance Mechanisms(46), Analytical Chemistry and Chromatography(45)

Publications618 total

Metronidazole Pharmacokinetics Across Species: Meta-Analysis Integrating Allometric Scaling and Minimal Physiologically-Based Pharmacokinetic Modeling
The AAPS Journal·2025Open Access
Exposure-response of serum biomarkers to vamorolone, a dissociative corticosteroidal anti-inflammatory drug, in 4- to <7-year children
Steroids·2025Open Access
Across‐Species Meta‐Analysis of Betamethasone Pharmacokinetics Utilizing a Minimal PBPK Model
Biopharmaceutics & Drug Disposition·2025
Insights Into Aldosterone Regulation Through Pharmacokinetic–Pharmacodynamic Modeling of an Aldosterone Synthase Inhibitor
Clinical Pharmacology & Therapeutics·2025· 1 citedOpen Access
A Step‐by‐Step Workflow for Performing In Silico Clinical Trials With Nonlinear Mixed Effects Models
CPT Pharmacometrics & Systems Pharmacology·2025Open Access
Meta-analysis of levamisole absorption and disposition across diverse species using a minimal physiologically-based pharmacokinetic model
Journal of Pharmaceutical Investigation·2025· 1 citedOpen Access
Response to “Misuse of the Term Biorhythms Undermines Chronological Research”
Clinical Pharmacology & Therapeutics·2025
Pharmacokinetic Assessment of Drug Efflux from Erythrocytes Loaded with Corticosteroid Esters
Pharmaceutical Research·2025Open Access
Review for "Phase I study of the oral <scp>GLP</scp>‐1 receptor agonist <scp>DA</scp>‐<scp>302168S</scp>: Safety, pharmacokinetics, and pharmacodynamics in healthy and overweight/obese adults"
2025
Whole-body physiologically based pharmacokinetic modeling of the nonlinear pharmacokinetics of prednisolone and its reversible metabolite prednisone in rats
Journal of Pharmacology and Experimental Therapeutics·2025
Hepatitis B <i>In Silico</i> Trials Capture Functional Cure, Indicate Mechanistic Pathways, and Suggest Prognostic Biomarker Signatures
Clinical Pharmacology & Therapeutics·2025· 4 citedOpen Access
Convergence of Several Biorhythms in Immunosuppressive Therapy for Liver Transplantation: Commentary on Ushijima <i>et al.</i>
Clinical Pharmacology & Therapeutics·2025· 2 cited
Fluconazole Dosing for the Prevention of Candida spp. Infections in Hemato-Oncologic Pediatric Patients: Population Pharmacokinetic Modeling and Probability of Target Attainment Simulations
Pharmaceutics·2025Open Access
Minimal Physiologically-Based Pharmacokinetic Modeling of Atenolol and Metoprolol Absorption in Malnourished Rats
European Journal of Drug Metabolism and Pharmacokinetics·2025· 4 citedOpen Access
Meta‐Analysis and Mechanism‐Based Modeling of Synovial and Plasma Pharmacokinetics and Adrenal Suppression Following Intra‐Articular Injection of Methylprednisolone Acetate in Horses
Journal of Veterinary Pharmacology and Therapeutics·2025· 1 citedOpen Access
Physiologically-based modeling of methylprednisolone pharmacokinetics across species with extrapolations to humans
Journal of Pharmaceutical Sciences·2025· 3 cited
Comparing the Efficacy of Various Insulin Types: Pharmacokinetic and Pharmacodynamic Modeling of Glucose Clamp Effects in Healthy Volunteers
The Journal of Clinical Pharmacology·2025Open Access
Novel computational workflow for selecting virtual patient cohorts for in silico clinical trials
2025
Meta-Analysis of the Input and Disposition of Various Dosage Forms of Methylprednisolone in Healthy Subjects Utilizing a Physiologically Based Pharmacokinetic Model
The AAPS Journal·2025· 1 citedOpen Access
Reply to: Comment: Cerebrospinal Fluid Pharmacokinetics of Nicardipine Following Intrathecal Administration in Subarachnoid Hemorrhage Patients
The Journal of Clinical Pharmacology·2024Open Access
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Frequent Co-authors

Jerome J. Schentag(5), Anthony M. Yurchak(5), Jeffrey R. Koup(4), Richard R. Almon(4), Debra C. DuBois(4), Donald E. Mager(3), James Q. Rose(3), Mark Gardner(2), Antoinette Mangione(2), John W. Vance(2), Yanguang Cao(2), Mark A. Milad(2), Robert A. Blum(2), Christian D. Lates(2), Gerhard Levy(2), Louise M. Gerbracht(2), Rohini Ramakrishnan(2), Nancy A. Pyszczynski(2), William E. Evans(1), Natalie Dayneka(1)