Lea Barfod

University of Copenhagen — Denmark

Medicine · Health Sciences

24h-index2.4kcitations59works3.62yr avg
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Research Topics

Malaria Research and Control(41), Mosquito-borne diseases and control(19), Complement system in diseases(18), HIV Research and Treatment(10), Monoclonal and Polyclonal Antibodies Research(6)

Publications59 total

Efficacy of ProC6C-AlOH/Matrix-M against Plasmodium falciparum infection and mosquito transmission: a phase 2, randomised, controlled human malaria infection study
The Lancet Infectious Diseases·2025· 1 cited
A monoclonal antibody selectively recognizing PfEMP1 proteins associated with cerebral malaria
Scientific Reports·2025Open Access
Cryo-EM led analysis of open and closed conformations of Chagas vaccine candidate TcPOP
Nature Communications·2025· 1 citedOpen Access
A monoclonal antibody selectively recognizing PfEMP1 proteins associated with cerebral malaria
2025Open Access
Deposition of complement regulators on the surface of Plasmodium falciparum merozoites depends on the immune status of the host
PLoS Pathogens·2025Open Access
Selection and characterization of a broadly neutralizing class of HCV anti-E2 VH1-69 antibodies
PLoS Pathogens·2025· 2 citedOpen Access
Broadly potent spike-specific human monoclonal antibodies inhibit SARS-CoV-2 Omicron sub-lineages
Communications Biology·2024· 3 citedOpen Access
Rational structure-guided design of a blood stage malaria vaccine immunogen presenting a single epitope from PfRH5
EMBO Molecular Medicine·2024· 8 citedOpen Access
Leveraging Immunofocusing and Virus-like Particle Display to Enhance Antibody Responses to the Malaria Blood-Stage Invasion Complex Antigen PfCyRPA
Vaccines·2024· 2 citedOpen Access
Development of an improved blood-stage malaria vaccine targeting the essential RH5-CyRPA-RIPR invasion complex
Nature Communications·2024· 27 citedOpen Access
Resolving multiple conformations of a sub-80 kDa Chagas vaccine candidate by cryo-EM led integrative approach
2024Open Access
Cryo-EM led analysis of open and closed conformations of Chagas vaccine candidate TcPOP and its antibody response characterisation
2024Open Access
Atypical memory B cell frequency correlates with antibody breadth and function in malaria immune adults
Scientific Reports·2024· 6 citedOpen Access
Development of an improved blood-stage malaria vaccine targeting the essential RH5-CyRPA-RIPR invasion complex
2024· 1 citedOpen Access
Novel, broad and potent spike-specific human monoclonal antibodies inhibit SARS-CoV-2 Omicron sub-lineages
Research Square (Research Square)·2023Open Access
Characterization of SARS‐CoV‐2 humoral immune response in a subject with unique sampling: A case report
Immunity Inflammation and Disease·2023· 1 citedOpen Access
A complex equation – adding to Plasmodium falciparum invasion
Trends in Parasitology·2023
Cryo-EM reveals the conformational epitope of human monoclonal antibody PAM1.4 broadly reacting with polymorphic malarial protein VAR2CSA
PLoS Pathogens·2022· 12 citedOpen Access
SARS-CoV-2 RBD-Specific Antibodies Induced Early in the Pandemic by Natural Infection and Vaccination Display Cross-Variant Binding and Inhibition
Viruses·2022· 5 citedOpen Access
Enhancing neutralization of Plasmodium falciparum using a novel monoclonal antibody against the rhoptry-associated membrane antigen
Scientific Reports·2022· 12 citedOpen Access
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Frequent Co-authors

Lars Hviid(22), Simon J. Draper(13), Michael F. Ofori(12), Matthew K. Higgins(11), Sarah E. Silk(10), Ali Salanti(9), Melanie R. Walker(8), Doris Quinkert(7), Ivan Campeotto(7), Maria Rosaria Bassi(6), Kazutoyo Miura(5), Alexander D. Douglas(5), Carole A. Long(5), Frederica Dedo Partey(5), Katherine E. Wright(5), Liz Stevenson(5), Anne Knudsen(5), Madeleine Dahlbäck(4), Louise Turner(4), Morten A. Nielsen(4)