Keiji Hirota

Kyoto University — Japan

Immunology and Microbiology · Life Sciences

37h-index12.5kcitations69works7.62yr avg
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Research Topics

T-cell and B-cell Immunology(38), Immune Cell Function and Interaction(29), Immunotherapy and Immune Responses(19), Psoriasis: Treatment and Pathogenesis(11), Immunodeficiency and Autoimmune Disorders(7)

Publications69 total

Regnase-1-mediated regulation of neutrophils modulates SARS-CoV-2 pneumonia
PLoS Pathogens·2026Open Access
Relationship between Phase Transition and Drug Release of Doxorubicin-Encapsulated Liposomes with Different Lipid Compositions Using Raman Spectroscopy
Biological and Pharmaceutical Bulletin·2025· 1 citedOpen Access
Stress-induced glucocorticoids enhance acute inflammation by promoting the differentiation of Th17 cells
Cell Reports·2025· 3 citedOpen Access
Type 17 immunity: novel insights into intestinal homeostasis and autoimmune pathogenesis driven by gut-primed T cells 
Cellular and Molecular Immunology·2024· 29 citedOpen Access
Ca <sup>2+</sup> -evoked sperm cessation determines embryo number in mammals
2024
Aberrant RNA sensing in regulatory T cells causes systemic autoimmunity
Science Advances·2024· 11 citedOpen Access
Notch2 with retinoic acid license IL-23 expression by intestinal EpCAM+ DCIR2+ cDC2s in mice
The Journal of Experimental Medicine·2024· 9 citedOpen Access
Targeting abatacept-resistant T-helper-17 cells by aldehyde dehydrogenase inhibition
iScience·2023· 1 citedOpen Access
Identification of Surface Markers and Functional Characterization of Myeloid Derived Suppressor Cell‐Like Adherent Cells
Advanced Biology·2023Open Access
Construction of a T cell receptor signaling range for spontaneous development of autoimmune disease
The Journal of Experimental Medicine·2022· 23 citedOpen Access
Attenuation of regulatory T cell function by type I IFN signaling in an MDA5 gain-of-function mutant mouse model
Biochemical and Biophysical Research Communications·2022· 3 citedOpen Access
Effect of Impaired T Cell Receptor Signaling on the Gut Microbiota in a Mouse Model of Systemic Autoimmunity
Arthritis & Rheumatology·2021· 37 cited
Dispensable roles of Gsdmd and Ripk3 in sustaining IL-1β production and chronic inflammation in Th17-mediated autoimmune arthritis
Scientific Reports·2021· 6 citedOpen Access
Distinct Foxp3 enhancer elements coordinate development, maintenance, and function of regulatory T cells
Immunity·2021· 74 citedOpen Access
Foxp3+ Regulatory T Cells Inhibit CCl4-Induced Liver Inflammation and Fibrosis by Regulating Tissue Cellular Immunity
Frontiers in Immunology·2020· 57 citedOpen Access
Impaired T cell receptor signaling and development of T cell–mediated autoimmune arthritis
Immunological Reviews·2020· 90 cited
Conversion of antigen-specific effector/memory T cells into Foxp3-expressing T <sub>reg</sub> cells by inhibition of CDK8/19
Science Immunology·2019· 125 cited
Synovial Tissue Inflammation Mediated by Autoimmune T Cells
Frontiers in Immunology·2019· 41 citedOpen Access
Identification of a genomic enhancer that enforces proper apoptosis induction in thymic negative selection
Nature Communications·2019· 23 citedOpen Access
Correction to: The pathogenicity of Th17 cells in autoimmune diseases
Seminars in Immunopathology·2019· 17 citedOpen Access
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Frequent Co-authors

Shimon Sakaguchi(21), Brigitta Stockinger(12), Takashi Nomura(10), Noriko Sakaguchi(10), Motomu Hashimoto(9), Marc Veldhoen(7), Keiko Yasuda(7), Yusuke Takeuchi(7), João H. Duarte(6), Hiroyuki Yoshitomi(6), Tomoyuki Yamaguchi(5), Yoshinaga Ito(5), Yohko Kitagawa(5), Hitomi Watanabe(5), Gen Kondoh(5), Helena Ahlfors(4), Shinji Maeda(4), Hiromu Ito(4), Satoshi Tanaka(4), Naganari Ohkura(4)