Margot Thome

University of Lausanne — Switzerland

Biochemistry, Genetics and Molecular Biology · Life Sciences

49h-index15.9kcitations159works0.42yr avg
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Research Topics

NF-κB Signaling Pathways(49), Cell death mechanisms and regulation(27), Immune Response and Inflammation(26), Immune Cell Function and Interaction(22), Lymphoma Diagnosis and Treatment(16)

Publications158 total

GLICOCORTICOIDES EM GESTANTES: ANÁLISE DO USO CLÍNICO E SEUS EFEITOS NA SAÚDE MATERNA
Revista Foco·2025Open Access
480 | LATENT MEMBRANE PROTEINS 1 AND 2 PROMOTE EBV‐MEDIATED B‐CELL TRANSFORMATION BY ACTIVATION OF THE PROTEASE MALT1
Hematological Oncology·2025Open Access
Binding of RHOA G17V to p300 enhances its HAT activity: a new mechanism of epigenetic deregulation in TFH lymphoma
Blood Advances·2025Open Access
The Protease MALT1 Uses K63-Linked and Linear Ubiquitin Chains to Facilitate Recruitment and Cleavage of Substrates Containing Ubiquitin Binding Domains
SSRN Electronic Journal·2025Open Access
PD1 inhibits PKCθ-dependent phosphorylation of cytoskeleton-related proteins and immune synapse formation
Blood Advances·2024· 2 citedOpen Access
Identification of Tensin-3 as a MALT1 substrate that controls B cell adhesion and lymphoma dissemination
Proceedings of the National Academy of Sciences·2023· 2 citedOpen Access
MALT-1 shortens lifespan by inhibiting autophagy in the intestine of <i>C. elegans</i>
Autophagy Reports·2023· 3 citedOpen Access
TCL-330 RHOA G17V Potentiates CD28-Induced NFAT Transcriptional Activity by Modulating p300 Activity: A Step Further in the Understanding of Follicular Helper T-Cell Lymphoma
Clinical Lymphoma Myeloma & Leukemia·2023
POSTER: TCL-330 RHOA G17V Potentiates CD28-Induced NFAT Transcriptional Activity by Modulating p300 Activity: A Step Further in the Understanding of Follicular Helper T-Cell Lymphoma
Clinical Lymphoma Myeloma & Leukemia·2023
Malt1-dependent cleavage of Tensin-3 controls B-cell adhesion and lymphomagenesis
2022Open Access
ASB2 is a direct target of FLI1 that sustains NF-κB pathway activation in germinal center-derived diffuse large B-cell lymphoma
Journal of Experimental & Clinical Cancer Research·2021· 13 citedOpen Access
Faculty Opinions recommendation of The E3 ligase HOIL-1 catalyses ester bond formation between ubiquitin and components of the Myddosome in mammalian cells.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2021
Faculty Opinions recommendation of T cell circuits that sense antigen density with an ultrasensitive threshold.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2021Open Access
Additional file 1 of ASB2 is a direct target of FLI1 that sustains NF-κB pathway activation in germinal center-derived diffuse large B-cell lymphoma
Figshare·2021Open Access
Faculty Opinions recommendation of Essential role of the linear ubiquitin chain assembly complex and TAK1 kinase in A20 mutant Hodgkin lymphoma.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2020
Abstract PO-07: The FLI1 direct target ASB2 promotes NF-KB pathway activation in diffuse large B-cell lymphoma of the germinal center B-cell type
Blood Cancer Discovery·2020
Therapeutic Potential of Targeting Malt1-Dependent TCR Downstream Signaling to Promote the Survival of MHC-Mismatched Allografts
Frontiers in Immunology·2020· 3 citedOpen Access
Faculty Opinions recommendation of Cbl and Cbl-b control the germinal center reaction by facilitating naive B cell antigen processing.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2020
Role of ETS1 in the Transcriptional Network of Diffuse Large B Cell Lymphoma of the Activated B Cell-Like Type
Cancers·2020· 10 citedOpen Access
Faculty Opinions recommendation of Two distinct ubiquitin-binding motifs in A20 mediate its anti-inflammatory and cell-protective activities.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2020
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Frequent Co-authors

Jürg Tschopp(20), Pascal Schneider(9), Kay Hofmann(8), Stephan Hailfinger(8), Fabio Martinon(7), Jean-Luc Bodmer(6), Georg Lenz(6), Kim Burns(5), Nils Holler(5), Martin Irmler(4), Michael Hahne(4), Michael Schröter(4), Chantal Mattmann(4), Olivier Gaide(4), Mélanie Juilland(4), Michael Grau(4), Peter Lenz(4), Véronique Steiner(3), Lars E. French(3), Olivier Micheau(3)