Zong‐Gen Peng

Chinese Academy of Medical Sciences & Peking Union Medical College — China

Medicine · Health Sciences

28h-index2.3kcitations128works8.32yr avg
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Research Topics

Hepatitis C virus research(45), Liver Disease Diagnosis and Treatment(30), Hepatitis B Virus Studies(21), HIV/AIDS drug development and treatment(18), Chemical synthesis and alkaloids(14)

Publications127 total

Effects of Chronic Moderate Alcohol Intake on Metabolic Phenotypes and Gut Microbiota in Lean and Obese Mice with Distinct Dietary Structures
Nutrients·2025Open Access
Berberine dissociates mitochondrial complex I by SIRT3-dependent deacetylation of NDUFS1 to improve hepatocellular glucose and lipid metabolism
Science China Life Sciences·2025· 8 cited
Potential Probiotics for the Therapy of Metabolic Dysfunction-Associated Steatotic Liver Disease
IntechOpen eBooks·2025· 1 citedOpen Access
Synthesis and evolution of 16-membered macrolide carrimycin derivatives as a novel class of anti-HCoV-OC43 agents targeting viral FSE RNA
European Journal of Medicinal Chemistry·2025· 2 cited
Tubulointerstitial nephritis antigen-like 1 promotes the progression of liver fibrosis after HCV eradication with direct-acting antivirals
International Journal of Biological Sciences·2025· 1 citedOpen Access
Lycorine esters exert anti-HCoV-OC43 effect through reversibly acylating cysteine residue in the nsp 12 NiRAN domain
Bioorganic Chemistry·2024· 1 cited
Author correction to “Up-regulation of glyclipid transfer protein by bicyclol causes spontaneous restriction of hepatitis C virus replication” [Acta Pharm Sin B 9 (2019) 769–781]
Acta Pharmaceutica Sinica B·2024Open Access
Discovery of Sporachelins by Genome Mining of a <i>Micromonospora</i> Strain
Journal of Natural Products·2024· 1 cited
Isoechinulin B, a natural product from Antarctic fungus, attenuates acute liver injury by inhibiting excessive cell adhesion
European Journal of Pharmacology·2024
ATG10S promotes IFNL1 expression and autophagic degradation of multiple viral proteins mediated by IFNL1
Autophagy·2024· 6 citedOpen Access
Upregulation of Hepatic Glutathione S-Transferase Alpha 1 Ameliorates Metabolic Dysfunction-Associated Steatosis by Degrading Fatty Acid Binding Protein 1
International Journal of Molecular Sciences·2024· 10 citedOpen Access
The novel small molecule E0924G dually regulates bone formation and bone resorption through activating the PPARδ signaling pathway to prevent bone loss in ovariectomized rats and senile mice
Bioorganic Chemistry·2024· 2 cited
Acremosides A–G, Sugar Alcohol-Conjugated Acyclic Sesquiterpenes from a Sponge-Derived <i>Acremonium</i> Species
Journal of Natural Products·2024· 9 cited
Discovery and development of novel 10,12-disubstituted aloperine derivatives against HCoV-OC43 by targeting allosteric site of host TMPRSS2
Bioorganic Chemistry·2024
Carrimycin inhibits coronavirus replication by decreasing the efficiency of programmed –1 ribosomal frameshifting through directly binding to the RNA pseudoknot of viral frameshift-stimulatory element
Acta Pharmaceutica Sinica B·2024· 12 citedOpen Access
<i>Bacteroides thetaiotaomicron</i> ameliorates mouse hepatic steatosis through regulating gut microbial composition, gut-liver folate and unsaturated fatty acids metabolism
Gut Microbes·2024· 92 citedOpen Access
Synthesis and Evolution of 16-Membered Macrolide Carrimycin Derivatives as a Novel Class of Anti-Hcov-Oc43 Agents Targeting Viral Fse Rna
SSRN Electronic Journal·2024Open Access
Mammalian antimicrobial peptides: defensins and cathelicidins
Elsevier eBooks·2024· 5 cited
Design, synthesis and biological evaluation of biaryl amide derivatives against SARS-CoV-2 with dual-target mechanism
European Journal of Medicinal Chemistry·2023· 1 citedOpen Access
Design, synthesis and triglyceride-lowering activity of tricyclic matrine derivatives for the intervention of non-alcoholic fatty liver disease
Bioorganic Chemistry·2023· 5 cited
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Frequent Co-authors

Jian‐Dong Jiang(33), Jianrui Li(14), Yuhuan Li(12), Danqing Song(11), Zhuorong Li(9), Hu Li(9), Biao Dong(8), Menghao Huang(7), Xiao‐Jiang Hao(7), Shan Cen(6), Yanxing Han(6), Ying‐Tong Di(6), Fei Liu(5), Jiali Tan(5), Jingpu Zhang(5), Mingming Cao(5), Xuekai Wang(4), Limei Gao(4), Yuping Wang(4), Nana Du(4)