Yan Chai

Northeast Agricultural University — China

Immunology and Microbiology · Life Sciences

35h-index3.6kcitations110works8.42yr avg
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Research Topics

Immunotherapy and Immune Responses(22), SARS-CoV-2 and COVID-19 Research(15), T-cell and B-cell Immunology(12), Immune Cell Function and Interaction(11), vaccines and immunoinformatics approaches(10)

Publications110 total

Neutrophil extracellular traps aggravate blood-brain barrier disruption via ZBP1/FSP1-mediated ferroptosis after traumatic brain injury
Fluids and Barriers of the CNS·2025· 1 citedOpen Access
Structural insights into IL-31 signaling inhibition by a neutralizing antibody
Structure·2025
Anti-M1R/B6R antibody characterization and bispecific design for enhanced orthopoxvirus protection
EMBO Molecular Medicine·2025· 1 citedOpen Access
Construction of an EGFP-embedded porcine reproductive and respiratory syndrome virus infectious clone and antiviral drug screening
Frontiers in Cellular and Infection Microbiology·2025Open Access
Neutrophils-astrocyte interactions in central nervous system inflammation
Cell Death and Disease·2025· 5 citedOpen Access
A metagenome-wide association study of gut microbiota in hepatitis B virus-related cirrhosis in northwest China
Frontiers in Genetics·2025· 1 citedOpen Access
An Engineered Soluble Single‐Chain TCR Engager for KRAS‐G12V Specific Tumor Immunotherapy
Advanced Science·2025· 1 citedOpen Access
Identification of causal plasma metabolite biomarkers for ischemic stroke using Mendelian randomization and mediation analysis
Scientific Reports·2025Open Access
Astrocyte-mediated inflammatory responses in traumatic brain injury: mechanisms and potential interventions
Frontiers in Immunology·2025· 24 citedOpen Access
Skull bone marrow and skull meninges channels: redefining the landscape of central nervous system immune surveillance
Cell Death and Disease·2025· 12 citedOpen Access
T cell immune evasion by SARS-CoV-2 JN.1 escapees targeting two cytotoxic T cell epitope hotspots
Nature Immunology·2025· 22 cited
Precise motif and cross-presentation of coronavirus peptides by feline MHC class I: implications for the mild infection of SARS-CoV-2
The Journal of Immunology·2025· 1 cited
Reimagining the meninges from a neuroimmune perspective: a boundary, but not peripheral
Journal of Neuroinflammation·2024· 11 citedOpen Access
Bispecific antibodies targeting two glycoproteins on SFTSV exhibit synergistic neutralization and protection in a mouse model
Proceedings of the National Academy of Sciences·2024· 23 citedOpen Access
Uncommon P1 Anchor-featured Viral T Cell Epitope Preference within HLA-A*2601 and HLA-A*0101 Individuals
ImmunoHorizons·2024· 3 citedOpen Access
Two noncompeting human neutralizing antibodies targeting MPXV B6 show protective effects against orthopoxvirus infections
Nature Communications·2024· 35 citedOpen Access
African swine fever virus A137R assembles into a dodecahedron cage
Journal of Virology·2024· 7 citedOpen Access
Structural basis and analysis of hamster ACE2 binding to different SARS-CoV-2 spike RBDs
Journal of Virology·2024· 5 citedOpen Access
Defining a de novo non-RBM antibody as RBD-8 and its synergistic rescue of immune-evaded antibodies to neutralize Omicron SARS-CoV-2
Proceedings of the National Academy of Sciences·2023· 33 citedOpen Access
Structural basis of Semliki Forest virus entry using the very-low-density lipoprotein receptor
hLife·2023· 9 citedOpen Access
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Frequent Co-authors

George F. Gao(37), Jianxun Qi(32), Shuguang Tan(18), Jinghua Yan(14), Kefang Liu(12), Hao Song(11), Yi Shi(11), Qihui Wang(10), Zhou Tong(7), William J. Liu(7), Xin Zhao(6), Feng Gao(6), Yan Wu(6), Mingming Shi(6), Jianning Zhang(6), Xin Chen(6), Shan Gao(5), Lili Wu(5), Liang Mi(5), Gary Wong(4)