Christopher B. Little

University of Sydney — Australia

Medicine · Health Sciences

69h-index16.4kcitations398works4.02yr avg
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Research Topics

Osteoarthritis Treatment and Mechanisms(204), Inflammatory mediators and NSAID effects(49), Tendon Structure and Treatment(45), Knee injuries and reconstruction techniques(42), Protease and Inhibitor Mechanisms(36)

Publications397 total

Reducing the burden of osteoarthritis in Australia: A 2024–2025 research priority-setting study
Osteoarthritis and Cartilage Open·2025Open Access
The Impact of the Ovine Annular Lesion Model on <scp>IVD</scp> Pathobiology and Utility of the Ovine Spinal Model in Patho‐Anatomical Studies: A Historical Perspective
JOR Spine·2025Open Access
Characterizing Focused Ultrasound-Induced Changes using 2-Photon Microscopy and MRI in a Mouse Model of Alzheimer’s Disease.
Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition·2025
Developing classification criteria for spine osteoarthritis: Is it the right time?
Osteoarthritis and Cartilage·2025· 1 cited
The utility of animal models in understanding osteoarthritis (OA) pathogenesis – an update on the impact of genetically modified mice
Connective Tissue Research·2025· 2 citedOpen Access
Synovial fluid as a complex molecular pool contributing to knee osteoarthritis
Nature Reviews Rheumatology·2025· 11 cited
AGE-ASSOCIATED PROTEOMIC CHANGES ACROSS KNEE JOINT COMPARTMENTS IN MICE
Osteoarthritis and Cartilage·2025
SEX DIFFERENCES IN OSTEOARTHRITIS PATHOLOGY, PAIN AND CIRCULATING MICRO-RNAS IN A PRECLINICAL MODEL OF INJURY-INDUCED OSTEOARTHRITIS.
Osteoarthritis and Cartilage·2025
Human iPSC-derived superficial-zone, deep-zone or hybrid chondrocyte organoids for osteochondral defect repair – first in-vivo study in rat
Osteoarthritis and Cartilage·2025
Structural Variations of Tendons: A Systematic Search and Narrative Review of Histological Differences Between Tendons, Tendon Regions, Sex, and Age
Journal of Orthopaedic Research®·2025· 6 citedOpen Access
The Biomechanical, Biochemical, and Morphological Properties of 19 Human Cadaveric Lower Limb Tendons and Ligaments: An Open-Access Data Set
The American Journal of Sports Medicine·2024· 8 cited
A standardized approach to evaluation and reporting of synovial histopathology in two surgically induced murine models of osteoarthritis
Osteoarthritis and Cartilage·2024· 15 citedOpen Access
BAD KNEES &amp; BROKEN HEARTS: miRs RELEASED FROM OSTEOARTHRITIC (OA) JOINTS INCREASE CARDIOVASCULAR DISEASE (CVD) RISK
Osteoarthritis and Cartilage·2024· 2 citedOpen Access
HUMAN CARTILAGE FROM THE UPPER AND LOWER LIMBS HAVE UNIQUE MECHANICAL PROPERTIES ACROSS DISTINCT JOINTS
Osteoarthritis and Cartilage·2024
Tendon biomechanical properties are altered by storage duration but not freeze‐thaw temperatures or cycles
Journal of Orthopaedic Research®·2024· 15 citedOpen Access
Loss of Grem1-lineage chondrogenic progenitor cells causes osteoarthritis
Nature Communications·2023· 33 citedOpen Access
Recommendations For a Standardized Approach to Histopathologic Evaluation of Synovial Membrane in Murine Models of Experimental Osteoarthritis
2023· 2 citedOpen Access
Streamlining quantitative joint-wide medial femoro-tibial histopathological scoring of mouse post-traumatic knee osteoarthritis models
Osteoarthritis and Cartilage·2023· 11 citedOpen Access
Disease-modifying interactions between chronic kidney disease and osteoarthritis: a new comorbid mouse model
RMD Open·2023· 18 citedOpen Access
Understanding the effects of mesenchymal stromal cell therapy for treating osteoarthritis using an in vitro co-culture model
European Cells and Materials·2023· 12 citedOpen Access
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Frequent Co-authors

Bruce Caterson(11), Clare Hughes(11), Carl R. Flannery(10), James Melrose(8), Susan M. Smith(8), Margaret M. Smith(8), Amanda Fosang(6), John F. Bateman(6), Martin Cake(5), C Curtis(4), R. A. Read(4), Peter J. Roughley(4), Colin Dent(4), Lynn Rowley(4), Clare T. Meeker(3), Daniele Belluoccio(3), S.S. Glasson(2), Heather Stanton(2), Fraser M. Rogerson(2), Suzanne B. Golub(2)