Kentaro Uemura

Hokkaido University of Science — Japan

Medicine · Health Sciences

19h-index1.8kcitations74works1.62yr avg
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Research Topics

SARS-CoV-2 and COVID-19 Research(16), Hepatitis C virus research(10), Mosquito-borne diseases and control(9), Viral gastroenteritis research and epidemiology(8), COVID-19 Clinical Research Studies(7)

Publications74 total

2-Thiouridine is a Broad-spectrum Antiviral Ribonucleoside Analogue Against Positive-strand RNA Viruses
YAKUGAKU ZASSHI·2025Open Access
SFTSV utilizes AXL/GAS6 for entry via PI3K-PLC-dependent macropinocytosis activated by AXL-kinase
Journal of Virology·2025· 1 citedOpen Access
Synergistic antiviral activity of a cathepsin B/L inhibitor and a TMPRSS2 inhibitor against SARS-CoV-2 in vitro and in vivo
Virology·2025
Establishment of a green fluorescent protein (GFP)-based reporter for picornaviral 3C proteases
2025Open Access
Enterovirus 3A protein disrupts endoplasmic reticulum homeostasis through interaction with GBF1
Journal of Virology·2024· 7 citedOpen Access
Electrolyzed hypochlorous acid water exhibits potent disinfectant activity against various viruses through irreversible protein aggregation
Frontiers in Microbiology·2023· 10 citedOpen Access
2-thiouridine is a broad-spectrum antiviral nucleoside analogue against positive-strand RNA viruses
Proceedings of the National Academy of Sciences·2023· 16 citedOpen Access
2-Thiouridine is a broad-spectrum antiviral nucleoside analogue against positive-strand RNA viruses
2022· 1 citedOpen Access
S-217622, a SARS-CoV-2 main protease inhibitor, decreases viral load and ameliorates COVID-19 severity in hamsters
Science Translational Medicine·2022· 91 citedOpen Access
Highly Potent and Oral Macrocyclic Peptides as a HIV-1 Protease Inhibitor: mRNA Display-Derived Hit-to-Lead Optimization
ACS Medicinal Chemistry Letters·2022· 22 citedOpen Access
Identification of cap-dependent endonuclease inhibitors with broad-spectrum activity against bunyaviruses
Proceedings of the National Academy of Sciences·2022· 19 citedOpen Access
Isolation and characterization of an orthoreovirus from Indonesian fruit bats
Virology·2022· 3 citedOpen Access
Efficacy of ensitrelvir against SARS-CoV-2 in a delayed-treatment mouse model
Journal of Antimicrobial Chemotherapy·2022· 32 citedOpen Access
Serological characterization of lineage II insect-specific flaviviruses compared with pathogenic mosquito-borne flaviviruses
Biochemical and Biophysical Research Communications·2022· 4 citedOpen Access
Pocket-to-Lead: Structure-Based <i>De Novo</i> Design of Novel Non-peptidic HIV-1 Protease Inhibitors Using the Ligand Binding Pocket as a Template
Journal of Medicinal Chemistry·2022· 9 citedOpen Access
Discovery of S-217622, a Noncovalent Oral SARS-CoV-2 3CL Protease Inhibitor Clinical Candidate for Treating COVID-19
Journal of Medicinal Chemistry·2022· 554 citedOpen Access
Oral administration of S-217622, a SARS-CoV-2 main protease inhibitor, decreases viral load and accelerates recovery from clinical aspects of COVID-19
2022· 12 citedOpen Access
Discovery of S-217622, a Non-Covalent Oral SARS-CoV-2 3CL Protease Inhibitor Clinical Candidate for Treating COVID-19
2022· 56 citedOpen Access
Synthesis and Anti-dengue Virus Activity of 5-Ethynylimidazole-4-carboxamide (EICA) Nucleotide Prodrugs
Chemical and Pharmaceutical Bulletin·2021· 4 citedOpen Access
5-Hydroxymethyltubercidin exhibits potent antiviral activity against flaviviruses and coronaviruses, including SARS-CoV-2
iScience·2021· 17 citedOpen Access
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Frequent Co-authors

Yasuko Orba(22), Hirofumi Sawa(22), Michihito Sasaki(20), Akihiko Sato(18), Shinsuke Toba(17), William W. Hall(17), Takao Sanaki(14), Haruaki Nobori(10), Yoshiharu Matsuura(10), Koshiro Tabata(9), Mai Kishimoto(9), Yukari Itakura(8), Chikako Ono(8), Katsumi Maenaka(7), Toru Okamoto(6), Teruhisa Kato(5), Shinji Kusakabe(5), Takao Shishido(5), Satomi Yamamoto(5), Takasuke Fukuhara(5)