Stephen L. Sturley

Columbia University — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

46h-index8.2kcitations99works0.02yr avg
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Research Topics

Lipid metabolism and biosynthesis(28), Cholesterol and Lipid Metabolism(23), Fungal and yeast genetics research(19), Endoplasmic Reticulum Stress and Disease(18), Lysosomal Storage Disorders Research(16)

Publications99 total

Arv1; a “Mover and Shaker” of Subcellular Lipids
Contact·2025Open Access
Identification and characterization of protein interactions with the major Niemann–Pick type C disease protein in yeast reveals pathways of therapeutic potential
Genetics·2023· 4 citedOpen Access
Ordinary differential equations to construct invertible generative models of cell type and tissue-specific regulatory networks
2023· 1 citedOpen Access
Potential COVID-19 therapeutics from a rare disease: weaponizing lipid dysregulation to combat viral infectivity
Journal of Lipid Research·2020· 50 citedOpen Access
Insights into possible COVID-19 antivirals from a rare neurodegenerative disease: an executive summary
2020· 2 citedOpen Access
Insights into the COVID-19 pandemic from a rare neurodegenerative disease
2020· 3 cited
The complexity of a monogenic neurodegenerative disease: More than two decades of therapeutic driven research into Niemann-Pick type C disease
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids·2019· 65 cited
Exacerbating and reversing lysosomal storage diseases: from yeast to humans
Microbial Cell·2017· 11 citedOpen Access
Normalization of Hepatic Homeostasis in the Npc1 Mouse Model of Niemann-Pick Type C Disease Treated with the Histone Deacetylase Inhibitor Vorinostat
Journal of Biological Chemistry·2016· 32 citedOpen Access
Expression of a cDNA derived from the yeast killer preprotoxin gene: Implications for processing and immunity (Saccharomyces cerevisiae/toxin/secretion/acid phosphatase/double-stranded RNA)
2016
Deletion of murine Arv1 results in a lean phenotype with increased energy expenditure
Nutrition and Diabetes·2015· 20 citedOpen Access
ATP‐binding cassette transporters and sterol <i>O</i> ‐acyltransferases interact at membrane microdomains to modulate sterol uptake and esterification
The FASEB Journal·2015· 24 cited
A Functional, Genome-wide Evaluation of Liposensitive Yeast Identifies the “RE2 Required for Viability” (ARV1) Gene Product as a Major Component of Eukaryotic Fatty Acid Resistance
Journal of Biological Chemistry·2013· 38 citedOpen Access
Mapping the functional yeast ABC transporter interactome
Nature Chemical Biology·2013· 84 citedOpen Access
Making, Baking, and Breaking: the Synthesis, Storage, and Hydrolysis of Neutral Lipids
Annual Review of Nutrition·2013· 51 cited
Upregulated function of mitochondria-associated ER membranes in Alzheimer disease
The EMBO Journal·2012· 626 citedOpen Access
Lipid droplet formation on opposing sides of the endoplasmic reticulum
Journal of Lipid Research·2012· 92 citedOpen Access
Abstract 58: Adipose-Specific Deletion of ARV1 Results in Decreased HDL Cholesterol, Reduced White Adipose Tissue Mass and Improved Glucose Tolerance in Mice
Arteriosclerosis Thrombosis and Vascular Biology·2012
PAH1-encoded phosphatidate phosphatase activity plays an essential role in protecting yeast against fatty acid-induced toxicity
Chemistry and Physics of Lipids·2011
Phosphatidate Phosphatase Activity Plays Key Role in Protection against Fatty Acid-induced Toxicity in Yeast
Journal of Biological Chemistry·2011· 129 citedOpen Access
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Frequent Co-authors

Peter Oelkers(9), Debra Cromley(6), Jeffrey T. Billheimer(6), Richard J. Deckelbaum(6), Martin Bard(6), Lisa J. Wilcox(6), Andrew B. Munkacsi(6), Arthur H. Tinkelenberg(5), Aaron Turkish(5), Mahajabeen Padamsee(4), Hongyuan Yang(4), Henry N. Ginsberg(4), Dina Balderes(4), Jeanne Garbarino(4), Kelly V. Ruggles(4), Annette L. Henneberry(4), Laura Liscum(3), Katsumi Higaki(3), Zhongmin Guo(3), Alan Attie(3)