Kristen L. Lauing

Loyola University Medical Center — United States

Medicine · Health Sciences

26h-index2.9kcitations158works1.02yr avg
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Research Topics

Glioma Diagnosis and Treatment(71), Tryptophan and brain disorders(53), Neuroinflammation and Neurodegeneration Mechanisms(32), Immune cells in cancer(28), Cancer Immunotherapy and Biomarkers(26)

Publications158 total

Supplementary Data T1 from Advanced Age in Humans and Mouse Models of Glioblastoma Show Decreased Survival from Extratumoral Influence
2025Open Access
Supplementary Data F1 from Advanced Age in Humans and Mouse Models of Glioblastoma Show Decreased Survival from Extratumoral Influence
2025Open Access
TMIC-14. A novel IDO1 PROTAC decreases immunosuppressive extracellular IDO1 levels
Neuro-Oncology·2025Open Access
Newly diagnosed glioblastoma IDHwt patients treated with radiation, nivolumab, and BMS-986205
2025Open Access
Indoleamine 2, 3 dioxygenase (IDO1) differentiallyModulates Microbial Aromatic Amino Acid Metabolites and Colonic Inflammation in an Age-Dependent Manner
Physiology·2025
Abstract 7373: The dual influence of treatment and age on survival in patients with glioblastoma
Cancer Research·2025
Abstract 6434: Senolytics decrease senescent microglia, remodel the vasculature, and improve survival in older adults with glioblastoma during co-treatment with immunotherapy
Cancer Research·2025
Abstract 2215: Age and indoleamine 2,3-dioxygenase 1 (IDO1) interact to affect gut microbiome homeostasis in subjects with glioblastoma
Cancer Research·2025
Rational Design and Optimization of a Potent IDO1 Proteolysis Targeting Chimera (PROTAC)
Journal of Medicinal Chemistry·2025· 15 citedOpen Access
Rational Design and Optimization of a Potent IDO1 Proteolysis Targeting Chimera (PROTAC)
2025Open Access
Supplementary Table 3 from Tumor Cell IDO Enhances Immune Suppression and Decreases Survival Independent of Tryptophan Metabolism in Glioblastoma
2024Open Access
Supplementary Figure 1 from Tumor Cell IDO Enhances Immune Suppression and Decreases Survival Independent of Tryptophan Metabolism in Glioblastoma
2024Open Access
Supplementary Figure 2 from Tumor Cell IDO Enhances Immune Suppression and Decreases Survival Independent of Tryptophan Metabolism in Glioblastoma
2024Open Access
Data from Tumor Cell IDO Enhances Immune Suppression and Decreases Survival Independent of Tryptophan Metabolism in Glioblastoma
2024Open Access
Supplementary Table 2 from Tumor Cell IDO Enhances Immune Suppression and Decreases Survival Independent of Tryptophan Metabolism in Glioblastoma
2024Open Access
Supplementary Table 4 from Tumor Cell IDO Enhances Immune Suppression and Decreases Survival Independent of Tryptophan Metabolism in Glioblastoma
2024Open Access
Supplementary Table 1 from Tumor Cell IDO Enhances Immune Suppression and Decreases Survival Independent of Tryptophan Metabolism in Glioblastoma
2024Open Access
CNSC-47. SENOLYTICS ERADICATE SENESCENT MICROGLIA IN THE BRAIN PARENCHYMA AND IMPROVE SURVIVAL IN OLDER ADULT MICE WITH GLIOBLASTOMA
Neuro-Oncology·2024Open Access
CNSC-38. INFLUENCE OF AGE, IMMUNOREGULATORY IDO, AND IMMUNOTHERAPY ON THE MICROBIOME IN MICE WITH AN EXPERIMENTAL BRAIN TUMOR
Neuro-Oncology·2024Open Access
Non-tumor cell IDO1 non-enzymatically decreases radiation + PD-1 mAb treatment efficacy in older adults with glioblastoma
The Journal of Immunology·2024Open Access
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Frequent Co-authors

Derek A. Wainwright(37), Lijie Zhai(36), Erik Ladomersky(25), Rimas V. Lukas(13), John J. Callaci(11), Alicia Lenzen(9), Galina Gritsina(9), April Bell(9), Craig Horbinski(8), David C. Binder(7), Jennifer D. Wu(7), Denise Scholtens(6), C. David James(6), Rintaro Hashizume(6), Rishi Lulla(6), Meijing Wu(5), Lakshmi Reddy Bollu(5), Gary E. Schiltz(5), Matthew Genet(5), Sebastian Otto‐Meyer(5)