Matthew Brown

Mount Sinai Hospital — United States

Medicine · Health Sciences

15h-index2.6kcitations55works1.32yr avg
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Research Topics

SARS-CoV-2 and COVID-19 Research(8), COVID-19 Clinical Research Studies(6), Cancer Immunotherapy and Biomarkers(6), Genetic factors in colorectal cancer(5), Immunotherapy and Immune Responses(4)

Publications55 total

Abstract C070: Targeting neoantigens conserved across organs and species overcomes tumor immune escape
Cancer Immunology Research·2026
Development of a Complementation Assay to Monitor Pan-Coronavirus 3C-like Protease Activity
Viruses·2026Open Access
Coordinated macrophage and T cell interactions mediate response to checkpoint blockade in colorectal cancer
2025Open Access
Identifying targets of precancerous neoantigen-specific T cell surveillance in patients with Lynch syndrome and immune suppression programs supporting colorectal cancer progression 3671
The Journal of Immunology·2025Open Access
Trophoblast stem cells and syncytiotrophoblasts lack inflammatory responses to LPS but retain robust interferon-mediated antiviral immunity
2025Open Access
T cell epitope mapping reveals immunodominance of evolutionarily conserved regions within SARS-CoV-2 proteome
iScience·2025· 1 citedOpen Access
Equity in cancer genomics in the UK: a cross-sectional analysis of a national cancer cohort
The Lancet Oncology·2025· 2 citedOpen Access
Apolipoprotein E selectively supports gammaherpesvirus replication in macrophages
Journal of Virology·2025Open Access
Coordinated macrophage and T cell interactions mediate response to checkpoint blockade in colorectal cancer
2025· 2 citedOpen Access
Faible taux d’uvéites chez les patients atteints de spondyloarthrite axiale ou de rhumatisme psoriasique traités par bimekizumab : résultats à long terme des essais de phase IIb/III
Revue du Rhumatisme·2024
1350 Dissecting immune surveillance and escape in Lynch syndrome patients
Regular and Young Investigator Award Abstracts·2024Open Access
T cell epitope mapping reveals immunodominance of evolutionarily conserved regions within SARS-CoV-2 proteome.
2024· 2 citedOpen Access
Mapping shared neoantigens and T-cell dysregulation in MSI-H endometrial cancer patients
Gynecologic Oncology·2024
Purpura fulminans in young women with influenza and co-infections
The Lancet·2024· 3 cited
Alternative RNA splicing generates shared clonal neoantigens across different types of cancer
Nature reviews. Immunology·2024· 10 cited
Faibles taux d’uvéites chez les patients atteints de spondyloarthrite axiale traités par bimékizumab : résultats regroupés des essais de phase IIb/III
Revue du Rhumatisme·2023
138 Shared frameshift neoantigens are expressed throughout mismatch repair deficient cancer development and are recognized by tissue infiltrating T cells that are dysregulated in advanced lesions
Regular and Young Investigator Award Abstracts·2023Open Access
S247 Surveillance of Frameshift Neoantigen-Specific T Cells During Tumor Development in Patients With Lynch Syndrome and Mismatch Repair Deficient Colorectal Cancer
The American Journal of Gastroenterology·2023
Immune escape and resistance to immunotherapy in mismatch repair deficient tumors
Frontiers in Immunology·2023· 80 citedOpen Access
Cancer immunity derailed: PGE2 misconducts cDC1s
Immunity·2023· 5 citedOpen Access
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Frequent Co-authors

Nina Bhardwaj(13), Cansu Cimen Bozkus(11), Leandra Velazquez(10), Robert Samstein(9), Aimee L. Lucas(6), Nicolas Vabret(5), Mesude Bicak(5), Alexandros D. Polydorides(5), Sharonne Holtzman(4), Miriam Saffern(3), Benjamin D. Greenbaum(3), Miriam Mérad(3), Julia Kodysh(3), San Kiang(3), Guillaume Mestrallet(3), Aideen McInerney‐Leo(3), Joyce Serebrenik(3), Mona Saleh(3), Natalie Vaninov(2), Azzeddine Lekhal(2)