Rosalba Perrone

Buck Institute for Research on Aging — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

24h-index3.6kcitations41works3.02yr avg
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Research Topics

DNA and Nucleic Acid Chemistry(23), RNA Interference and Gene Delivery(19), Advanced biosensing and bioanalysis techniques(11), HIV Research and Treatment(8), Calcium signaling and nucleotide metabolism(6)

Publications41 total

CD38 Inhibition Ameliorates Age-Related Cognitive Decline via a Choroid Plexus–Cerebrospinal Fluid–Hippocampus Axis
2026Open Access
G-Quadruplex Folding Enforces HIV-1 Transcriptional Latency via Nucleolin Recruitment
2025· 1 citedOpen Access
Naphthalene Diimide–Tetraazacycloalkane Conjugates Are G-Quadruplex-Based HIV-1 Inhibitors with a Dual Mode of Action
ACS Infectious Diseases·2024· 8 citedOpen Access
CD38 regulates ovarian function and fecundity via NAD+ metabolism
iScience·2023· 26 citedOpen Access
POS1022 A NEWLY DEVELOPED SMALL MOLECULE CD38 INHIBITOR EXERTS THERAPEUTIC EFFECTS IN A COLLAGEN-INDUCED ARTHRITIS MOUSE MODEL
Annals of the Rheumatic Diseases·2023· 2 citedOpen Access
CD38 regulates ovarian function and fecundity via NAD <sup>+</sup> metabolism
2023· 2 citedOpen Access
Fused in Liposarcoma Protein, a New Player in the Regulation of HIV-1 Transcription, Binds to Known and Newly Identified LTR G-Quadruplexes
ACS Infectious Diseases·2022· 26 citedOpen Access
Targeting Conserved Sequences Circumvents the Evolution of Resistance in a Viral Gene Drive against Human Cytomegalovirus
Journal of Virology·2021· 11 citedOpen Access
Antiviral Activity of the G-Quadruplex Ligand TMPyP4 against Herpes Simplex Virus-1
Viruses·2021· 44 citedOpen Access
Targeting conserved sequences circumvents the evolution of resistance in a viral gene drive against human cytomegalovirus
2021Open Access
NAD+ metabolism and its roles in cellular processes during ageing
Nature Reviews Molecular Cell Biology·2020· 1.3k citedOpen Access
Author Correction: Senescent cells promote tissue NAD+ decline during ageing via the activation of CD38+ macrophages
Nature Metabolism·2020· 9 citedOpen Access
Senescent cells promote tissue NAD+ decline during ageing via the activation of CD38+ macrophages
Nature Metabolism·2020· 382 citedOpen Access
FOXO1 promotes HIV latency by suppressing ER stress in T cells
Nature Microbiology·2020· 35 citedOpen Access
FOXO1 promotes HIV Latency by suppressing ER stress in T cells
2020· 5 citedOpen Access
Stable and Conserved G-Quadruplexes in the Long Terminal Repeat Promoter of Retroviruses
ACS Infectious Diseases·2019· 46 citedOpen Access
Aging-related inflammation driven by cellular senescence enhances NAD consumption via activation of CD38 <sup>+</sup> pro-inflammatory macrophages
2019· 14 citedOpen Access
G-quadruplex forming sequences in the genome of all known human viruses: A comprehensive guide
PLoS Computational Biology·2018· 144 citedOpen Access
G-quadruplex forming sequences in the genome of all known human viruses: a comprehensive guide
2018· 36 citedOpen Access
Mapping and characterization of G-quadruplexes in Mycobacterium tuberculosis gene promoter regions
Scientific Reports·2017· 89 citedOpen Access
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Frequent Co-authors

Sara N. Richter(26), Giorgio Palù(16), Ilaria Frasson(15), Matteo Nadai(14), Eric Verdin(11), Elena Butovskaya(8), Herbert G. Kasler(5), Rebeccah Riley(5), Mélanie Ott(5), Manlio Palumbo(5), Matteo Scalabrin(5), Filippo Doria(5), Emanuela Ruggiero(5), Anthony J. Covarrubias(4), Indra Heckenbach(4), Birgit Schilling(4), Sara Artusi(4), Enrico Lavezzo(4), Sara Lago(4), Mauro Freccero(4)