Helmut W. Kessels

Netherlands Institute for Neuroscience — Netherlands

Neuroscience · Life Sciences

30h-index4.9kcitations58works17.12yr avg
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Research Topics

Neuroscience and Neuropharmacology Research(30), Alzheimer's disease research and treatments(16), Memory and Neural Mechanisms(12), T-cell and B-cell Immunology(8), CAR-T cell therapy research(8)

Publications58 total

Activation of Epac2 improves Aβ-induced impairment of memory retrieval in an acute model of Alzheimer's disease
Neuropharmacology·2025· 1 citedOpen Access
GluA1-containing AMPA receptors are necessary for sparse memory engram formation
Neurobiology of Learning and Memory·2025Open Access
Amyloid-β-Driven Synaptic Deficits Are Mediated by Synaptic Removal of GluA3-Containing AMPA Receptors
Journal of Neuroscience·2025· 5 citedOpen Access
How Can Early Stress Influence Later Alzheimer's Disease Risk? Possible Mediators and Underlying Mechanisms
Biological Psychiatry·2024· 5 citedOpen Access
The concept of resilience to Alzheimer’s Disease: current definitions and cellular and molecular mechanisms
Molecular Neurodegeneration·2024· 55 citedOpen Access
Overnight neuronal plasticity and adaptation to emotional distress
Nature reviews. Neuroscience·2024· 48 citedOpen Access
M13 phage grafted with peptide motifs as a tool to detect amyloid-β oligomers in brain tissue
Communications Biology·2024· 6 citedOpen Access
Early life stress lastingly alters the function and <scp>AMPA</scp> ‐receptor composition of glutamatergic synapses in the hippocampus of male mice
Journal of Neuroendocrinology·2023· 6 cited
Author response for "Early life stress lastingly alters the function and &lt;scp&gt;AMPA&lt;/scp&gt;‐receptor composition of glutamatergic synapses in the hippocampus of male mice"
2023
The Expression of Epac2 and GluA3 in an Alzheimer’s Disease Experimental Model and Postmortem Patient Samples
Biomedicines·2023· 4 citedOpen Access
Variance analysis as a method to predict the locus of plasticity at populations of non-uniform synapses
Frontiers in Cellular Neuroscience·2023· 1 citedOpen Access
Resilience in Alzheimer's disease: Gene expression patterns in individuals with a discrepancy between ante‐mortem cognition and post‐mortem pathology
Alzheimer s & Dementia·2021Open Access
β-amyloid−driven synaptic depression requires PDZ protein interaction at AMPA-receptor subunit GluA3
2021Open Access
Measuring Behavior in the Home Cage: Study Design, Applications, Challenges, and Perspectives
Frontiers in Behavioral Neuroscience·2021· 102 citedOpen Access
Seizure-mediated iron accumulation and dysregulated iron metabolism after status epilepticus and in temporal lobe epilepsy
Acta Neuropathologica·2021· 81 citedOpen Access
PSD-95 protects synapses from β-amyloid
Cell Reports·2021· 123 citedOpen Access
Review for "Molecular mechanisms of forgetting"
2020
Plasticiteit in de hersenen; synaptische plasticiteit en adulte neurogenese
Data Archiving and Networked Services (DANS)·2020
Variance analysis as a tool to predict the mechanism underlying synaptic plasticity
Journal of Neuroscience Methods·2019· 18 citedOpen Access
The Effects of Sindbis Viral Vectors on Neuronal Function
Frontiers in Cellular Neuroscience·2019· 12 citedOpen Access
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Frequent Co-authors

Roberto Malinow(11), Ton N. Schumacher(9), Niels R. Reinders(6), Maria Renner(5), Paul J. Lucassen(5), August B. Smit(5), Karin J. Koymans(4), Dick F. Swaab(4), Harm J. Krugers(4), Aile N. van Huijstee(4), Ada M. Kruisbeek(4), Sadegh Nabavi(3), Stephanie Alfonso(3), Monika C. Wolkers(3), Marly D. van den Boom(3), Charles D. Kopec(3), Tessa R Lodder(3), Nicolás Gutiérrez‐Castellanos(3), Sylvie L. Lesuis(3), Anikó Kőrösi(3)