Toshimitsu Komatsu

Nagasaki University — Japan

Medicine · Health Sciences

23h-index1.4kcitations46works0.02yr avg
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Research Topics

Adipose Tissue and Metabolism(23), Dietary Effects on Health(15), Genetics, Aging, and Longevity in Model Organisms(14), Regulation of Appetite and Obesity(8), Diet and metabolism studies(8)

Publications45 total

The Role of Neuropeptide Y in Adipocyte-Macrophage Crosstalk during High Fat Diet-Induced Adipose Inflammation and Liver Steatosis
Biomedicines·2021· 10 citedOpen Access
Effects of rikkunshito supplementation on resistance to oxidative stress and lifespan in mice
Geriatrics and gerontology international/Geriatrics & gerontology international·2019· 5 cited
Mechanisms of Calorie Restriction: A Review of Genes Required for the Life-Extending and Tumor-Inhibiting Effects of Calorie Restriction
Nutrients·2019· 38 citedOpen Access
Mitochondria morphology alteration in liver of miR-142-deficient mice
The Molecular Biology Society of Japan·2019
Neuropeptide Y inhibits hepatocarcinogenesis in overnutrition in mice
2019· 1 cited
NPY Deficiency Prevents Postmenopausal Adiposity by Augmenting Estradiol-Mediated Browning
The Journals of Gerontology Series A·2018· 8 citedOpen Access
Targeting <i>miR‐223</i> in neutrophils enhances the clearance of <i>Staphylococcus aureus</i> in infected wounds
EMBO Molecular Medicine·2018· 57 citedOpen Access
ROLES FOR FOXO1 AND FOXO3 IN REGULATION OF CANCER AND LIFESPAN IN DIETARY-RESTRICTED MICE
Innovation in Aging·2017Open Access
REGULATION OF LIPOLYTIC CONTROL BY NEUROPEPTIDE Y PROMOTES SURVIVAL IN CALORIE-RESTRICTED MICE
Innovation in Aging·2017Open Access
Neuropeptide Y resists excess loss of fat by lipolysis in calorie-restricted mice: a trait potential for the life-extending effect of calorie restriction
Aging Cell·2017· 24 citedOpen Access
MiR-142 Is Required for Staphylococcus aureus Clearance at Skin Wound Sites via Small GTPase-Mediated Regulation of the Neutrophil Actin Cytoskeleton
Journal of Investigative Dermatology·2016· 56 citedOpen Access
Upregulation of cytochrome c oxidase subunit 6b1 (Cox6b1) and formation of mitochondrial supercomplexes: implication of Cox6b1 in the effect of calorie restriction
AGE·2015· 33 citedOpen Access
The life‐extending effect of dietary restriction requires <scp>F</scp> oxo3 in mice
Aging Cell·2015· 106 citedOpen Access
Overexpression of the adiponectin gene mimics the metabolic and stress resistance effects of calorie restriction, but not the anti-tumor effect
Experimental Gerontology·2015· 3 citedOpen Access
NPY antagonism reduces adiposity and attenuates age‐related imbalance of adipose tissue metabolism
The FASEB Journal·2014· 43 cited
Reduced FOXO1 Expression Accelerates Skin Wound Healing and Attenuates Scarring
American Journal Of Pathology·2014· 65 citedOpen Access
A key role for neuropeptide Y in lifespan extension and cancer suppression via dietary restriction
Scientific Reports·2014· 47 citedOpen Access
Nutrient‐dependent requirement for SOD1 in lifespan extension by protein restriction in <i>Drosophila melanogaster</i>
Aging Cell·2012· 50 citedOpen Access
Modest inhibition of the growth hormone axis does not affect mitochondrial reactive oxygen species generation or redox state, unlike calorie restriction
Geriatrics and gerontology international/Geriatrics & gerontology international·2011· 5 cited
Acute stress response modified by modest inhibition of growth hormone axis: A potential machinery of the anti-aging effect of calorie restriction
Mechanisms of Ageing and Development·2011· 6 cited
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Frequent Co-authors

Isao Shimokawa(43), Takuya Chiba(31), Hiroko Hayashi(26), Haruyoshi Yamaza(24), Ryoichi Mori(21), Yoshikazu Higami(17), Seongjoon Park(16), Sang Eun Kim(8), Tomoshi Tsuchiya(6), Katsuya Tanaka(5), Seong‐Joon Park(5), Kazuo To(4), Hiroaki Toyama(4), Lucas Siqueira Trindade(4), Katsumi Tanaka(3), Kazuya Ikematsu(3), Paul Martin(3), Takahiro Hayashida(3), Satoshi Fujita(3), Kazunao Kuramoto(3)