Lindsey N. Young

UC San Diego Health System — United States

Medicine · Health Sciences

13h-index1.8kcitations32works0.72yr avg
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Research Topics

Autophagy in Disease and Therapy(10), CRISPR and Genetic Engineering(7), Advanced Electron Microscopy Techniques and Applications(5), Endoplasmic Reticulum Stress and Disease(4), Electron and X-Ray Spectroscopy Techniques(4)

Publications32 total

ExoSloNano: multimodal nanogold labels for identification of macromolecules in live cells and cryo-electron tomograms
Nature Methods·2025· 1 citedOpen Access
Cryo-tomography of 1.4 nm-HAN-594 labeled nucleosomes inside cells (ExoSloNano)
EMPIAR dataset·2025Open Access
Cryo-tomography of 1.4 nm-HAN-488 labeled ribosomes inside cells (ExoSloNano)
EMPIAR dataset·2025Open Access
Cryo-tomography of 5 nm Nanogold labeled ribosomes from intact cells (ExoSloNano)
EMPIAR dataset·2025Open Access
A Multi-Modal and Generalizable Nanogold Tag for Cryo-Electron Tomography in Intact Cells
Structural Dynamics·2025Open Access
ExoSloNano: Multi-Modal Nanogold Tags for identification of Macromolecules in Live Cells & Cryo-Electron Tomograms
2024· 4 citedOpen Access
A generalized nanogold tagging system for the identification of macromolecules in in situ tomograms
Biophysical Journal·2024Open Access
GIANT ADRENAL SCHWANNOMA PRESENTING AS ADRENAL INCIDENTALOMA WITH MALIGNANT FEATURES
Journal of the ASEAN Federation of Endocrine Societies·2023Open Access
Bringing Structure to Cell Biology with Cryo-Electron Tomography
Annual Review of Biophysics·2023· 123 citedOpen Access
59 The stem cell unrelated donor search during COVID19
Digital posters·2023
Versatile nanogold tagging system applied to the identification of heterochromatin through cryo-FIB-ET
Biophysical Journal·2023
ULK complex organization in autophagy by a C-shaped FIP200 N-terminal domain dimer
The Journal of Cell Biology·2020· 94 citedOpen Access
ULK complex organization in autophagy by a C-shaped FIP200 N-terminal domain dimer
2019· 14 citedOpen Access
Structural mechanism of a Rag GTPase activation checkpoint by the lysosomal folliculin complex
Science·2019· 168 citedOpen Access
Structural pathway for allosteric activation of the autophagic PI 3-kinase complex I
Proceedings of the National Academy of Sciences·2019· 52 citedOpen Access
Structural Pathway for Allosteric Activation of the Autophagic PI 3-Kinase Complex I
2019Open Access
The BARA necessities of PtdIns 3-kinase activation in autophagy
Autophagy·2019· 5 citedOpen Access
Bidirectional Control of Autophagy by BECN1 BARA Domain Dynamics
Molecular Cell·2018· 81 cited
Mechanisms of Autophagy Initiation
Annual Review of Biochemistry·2017· 638 citedOpen Access
Abstract P3-04-16: Steroid receptor co-activator 1 mediation of cancer cell reprogramming in endocrine resistant breast cancer
Cancer Research·2017
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Frequent Co-authors

James H. Hurley(11), Elizabeth Villa(9), Joshua Hutchings(8), Alice Sherrard(5), Antonio J. Giráldez(4), Meena L. Narasimhan(4), M Riggi(4), Goran Stjepanović(3), Adam L. Yokom(3), Bentley A. Fane(3), Huabin Zhou(3), Farhaz Shaikh(3), Michael K. Rosen(3), Eric J. Bennett(3), A Sherard(3), Flaherty WA(3), Rosen MK(3), Huan‐Xiang Zhou(3), Shaikh F(3), Sulochanadevi Baskaran(2)