Salvatore Spina

University of California, San Francisco — United States

Medicine · Health Sciences

64h-index24.9kcitations304works5.32yr avg
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Research Topics

Alzheimer's disease research and treatments(157), Dementia and Cognitive Impairment Research(72), Parkinson's Disease Mechanisms and Treatments(63), Amyotrophic Lateral Sclerosis Research(55), Neurological diseases and metabolism(27)

Publications281 total

Focus on orexinergic neurons: omics study reveals glial changes and neuroinflammation in the lateral hypothalamic area as key factors driving the initial vulnerability in Alzheimer's disease
Alzheimer s & Dementia·2025Open Access
Single‐nuclei transcriptomic identifies neuronal populations vulnerable to AD by leveraging AD variants
Alzheimer s & Dementia·2025Open Access
MTBR‐tau243 biomarker specifically identifies mixed 3R/4R tauopathies
Alzheimer s & Dementia·2025Open Access
FTLD‐TDP versus LATE‐NC: The UCSF Neurodegenerative Disease Brain Bank Experience
Alzheimer s & Dementia·2025Open Access
Robust associations with posterior predominant amyloid PET binding
Alzheimer s & Dementia·2025Open Access
Circadian‐regulating nuclei in the human anterior hypothalamus demonstrate selective vulnerability to pathological effects of Alzheimer's disease
Alzheimer s & Dementia·2025Open Access
Selective tau vulnerability in the human master circadian clock in atypical Alzheimer's disease
Alzheimer s & Dementia·2025Open Access
Beyond <i>p</i> ‐Tau: Unveiling Caspase‐6 Truncated Tau as an Early and Distinct Pathological Marker in Alzheimer's Disease
Alzheimer s & Dementia·2025Open Access
Neuropathological comorbidities in Frontotemporal Lobar Degeneration: Implications for Diagnosis
Alzheimer s & Dementia·2025Open Access
Heterogeneous tau patterns in atypical AD are explained by connectivity‐associated tau progression
Alzheimer s & Dementia·2025Open Access
Unveiling the distinct roles of <i>p</i> ‐tau, iron and MAOB in neurobiological basis of F18‐flortaucipir signal with voxel‐to‐voxel histology to PET analysis in different tauopathies
Alzheimer s & Dementia·2025Open Access
Robust associations with posterior predominant amyloid PET binding
Alzheimer s & Dementia·2025Open Access
TAF15 amyloids propagate via defined motifs in a prion-like fashion
2025· 1 citedOpen Access
G-protein-coupled receptor ADGRG1 drives a protective microglial state in Alzheimer’s disease through MYC activation
Neuron·2025Open Access
Agentic Generative Artificial Intelligence System for Classification of Pathology-Confirmed Primary Progressive Aphasia Variants
2025Open Access
Exploring Centiloid Robustness: Impact of Sample Size and Image Resolution on Centiloid Conversion Accuracy
Journal of Nuclear Medicine·2025· 2 cited
Burden of psychiatric disease inversely correlates with Alzheimer's age at onset
Alzheimer s & Dementia·2025· 1 citedOpen Access
Celebrating neuropathology's contributions to Alzheimer's Disease Research Centers
Alzheimer s & Dementia·2025· 3 citedOpen Access
Combining plasma neurofilament light chain and frontotemporal atrophy improves differentiation of bvFTD from primary psychiatric disorders
Alzheimer s & Dementia·2025· 1 citedOpen Access
Pathogenic tau inhibits synaptic plasticity by blocking eIF4B-mediated local protein synthesis
2025· 3 citedOpen Access
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Frequent Co-authors

Bruce L. Miller(27), Lea T. Grinberg(26), William W. Seeley(25), Bernardino Ghetti(22), Adam L. Boxer(15), Dennis W. Dickson(13), Bradley F. Boeve(12), Gil D. Rabinovici(12), Howard J. Rosen(12), Jordan Grafman(11), John Q. Trojanowski(9), Jill R. Murrell(9), Matt Baker(8), Edward D. Huey(8), Eileen H. Bigio(7), Nigel J. Cairns(7), Glenda M. Halliday(7), Renaud La Joie(7), Anna M. Karydas(7), Joel H. Kramer(7)